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Related papers: Multimap targeted free energy estimation

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Nonequilibrium, ``fast switching'' estimates of equilibrium free energy differences, Delta F, are often plagued by poor convergence due to dissipation. We propose a method to improve these estimates by generating trajectories with reduced…

Statistical Mechanics · Physics 2009-11-13 Suriyanarayanan Vaikuntanathan , Christopher Jarzynski

We revisit the proof of the limiting free energy of the continuous random energy model (CREM) using the Hamilton--Jacobi approach for mean-field disordered systems. To achieve this, we introduce an enriched model that interpolates between…

Probability · Mathematics 2025-08-26 Alexander Alban , Fu-Hsuan Ho , Justin Ko

In many statistical learning problems, the target functions to be optimized are highly non-convex in various model spaces and thus are difficult to analyze. In this paper, we compute \emph{Energy Landscape Maps} (ELMs) which characterize…

Machine Learning · Statistics 2014-10-03 Maria Pavlovskaia , Kewei Tu , Song-Chun Zhu

In this paper, we develop an iterative scheme to construct multiscale basis functions within the framework of the Constraint Energy Minimizing Generalized Multiscale Finite Element Method (CEM-GMsFEM) for the mixed formulation. The…

Numerical Analysis · Mathematics 2020-12-04 Siu Wun Cheung , Eric Chung , Yalchin Efendiev , Wing Tat Leung , Sai-Mang Pun

In this paper, we present two multidimensional power flow formulations based on a fixed-point iteration (FPI) algorithm to efficiently solve hundreds of thousands of power flows in distribution systems. The presented algorithms are the base…

Systems and Control · Electrical Eng. & Systems 2024-03-08 Edgar Mauricio Salazar Duque , Juan S. Giraldo , Pedro P. Vergara , Phuong H. Nguyen , Han , Slootweg

The shift in chemical equilibria due to isotope substitution is often exploited to gain insight into a wide variety of chemical and physical processes. It is a purely quantum mechanical effect, which can be computed exactly using…

Statistical Mechanics · Physics 2014-07-04 Michele Ceriotti , Thomas E. Markland

Quantum embedding schemes have the potential to significantly reduce the computational cost of first principles calculations, whilst maintaining accuracy, particularly for calculations of electronic excitations in complex systems. In this…

Materials Science · Physics 2022-03-10 Joseph C. A. Prentice

We introduce a new class of machine learning interatomic potentials - fast General Two- and Three-body Potential (GTTP), which is as fast as conventional empirical potentials and require computational time that remains constant with…

Computational Physics · Physics 2023-01-03 Sergey Pozdnyakov , Artem R. Oganov , Efim Mazhnik , Arslan Mazitov , Ivan Kruglov

The Free Energy Principle (FEP) is a theoretical framework for describing how (intelligent) systems self-organise into coherent, stable structures by minimising a free energy functional. Active Inference (AIF) is a corollary of the FEP that…

Artificial Intelligence · Computer Science 2023-10-17 Magnus Koudahl , Thijs van de Laar , Bert de Vries

The accuracy of any machine learning potential can only be as good as the data used in the fitting process. The most efficient model therefore selects the training data that will yield the highest accuracy compared to the cost of obtaining…

Chemical Physics · Physics 2020-07-21 Anders S. Christensen , O. Anatole von Lilienfeld

Systematic inaccuracy is inherent in any computational estimate of a non-linear average, due to the availability of only a finite number of data values, N. Free energy differences (DF) between two states or systems are critically important…

Computational Physics · Physics 2009-11-07 Daniel M. Zuckerman , Thomas B. Woolf

Deep energy-based models are powerful, but pose challenges for learning and inference (Belanger and McCallum, 2016). Tu and Gimpel (2018) developed an efficient framework for energy-based models by training "inference networks" to…

Computation and Language · Computer Science 2020-10-13 Lifu Tu , Richard Yuanzhe Pang , Kevin Gimpel

Linear mixed models (LMMs) have emerged as the method of choice for confounded genome-wide association studies. However, the performance of LMMs in non-randomly ascertained case-control studies deteriorates with increasing sample size. We…

Genomics · Quantitative Biology 2016-02-23 Omer Weissbrod , Christoph Lippert , Dan Geiger , David Heckerman

The latest industrial inference engines, such as FasterTransformer and TurboTransformers, have verified that half-precision floating point (FP16) and 8-bit integer (INT8) quantization can greatly improve model inference speed. However, the…

Machine Learning · Computer Science 2023-12-19 Rong Tian , Zijing Zhao , Weijie Liu , Haoyan Liu , Weiquan Mao , Zhe Zhao , Kan Zhou

We present an ab initio approach for evaluating a free energy profile along a reaction coordinate by combining logarithmic mean force dynamics (LogMFD) and first-principles molecular dynamics. The mean force, which is the derivative of the…

Chemical Physics · Physics 2014-05-29 Makoto Nakamura , Masao Obata , Tetsuya Morishita , Tatsuki Oda

How the brain performs credit assignment is a fundamental unsolved problem in neuroscience. Many `biologically plausible' algorithms have been proposed, which compute gradients that approximate those computed by backpropagation (BP), and…

Machine Learning · Computer Science 2022-08-05 Beren Millidge , Yuhang Song , Tommaso Salvatori , Thomas Lukasiewicz , Rafal Bogacz

Optimal planning with respect to learned neural network (NN) models in continuous action and state spaces using mixed-integer linear programming (MILP) is a challenging task for branch-and-bound solvers due to the poor linear relaxation of…

Artificial Intelligence · Computer Science 2019-07-29 Buser Say , Scott Sanner , Sylvie Thiébaux

Recent approaches to efficiently ensemble neural networks have shown that strong robustness and uncertainty performance can be achieved with a negligible gain in parameters over the original network. However, these methods still require…

Computing free energy is a fundamental problem in statistical physics. Recently, two distinct methods have been developed and have demonstrated remarkable success: the tensor-network-based contraction method and the neural-network-based…

Statistical Mechanics · Physics 2025-04-17 Hanyan Cao , Yijia Wang , Feng Pan , Pan Zhang

Price signals from distribution networks (DNs) guide energy communities (ECs) in adjusting their energy usage, enabling effective coordination for reliable power system operation. However, this coordinated operation faces significant…

Optimization and Control · Mathematics 2026-03-02 Yingrui Zhuang , Lin Cheng , Yuji Cao , Tongxin Li , Ning Qi , Yan Xu , Yue Chen
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