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The proliferation of Large Language Models (LLMs) in medicine has enabled impressive capabilities, yet a critical gap remains in their ability to perform systematic, transparent, and verifiable reasoning, a cornerstone of clinical practice.…

Computation and Language · Computer Science 2025-08-04 Wenxuan Wang , Zizhan Ma , Meidan Ding , Shiyi Zheng , Shengyuan Liu , Jie Liu , Jiaming Ji , Wenting Chen , Xiang Li , Linlin Shen , Yixuan Yuan

Ontologies play a crucial role in organizing and representing knowledge. However, even current ontologies do not encompass all relevant concepts and relationships. Here, we explore the potential of large language models (LLM) to expand an…

Computation and Language · Computer Science 2023-11-14 Antonio Zaitoun , Tomer Sagi , Szymon Wilk , Mor Peleg

This survey and application guide to multimodal large language models(MLLMs) explores the rapidly developing field of MLLMs, examining their architectures, applications, and impact on AI and Generative Models. Starting with foundational…

Artificial Intelligence · Computer Science 2025-12-02 Chia Xin Liang , Pu Tian , Caitlyn Heqi Yin , Yao Yua , Wei An-Hou , Li Ming , Xinyuan Song , Tianyang Wang , Ziqian Bi , Ming Liu

The control of complex laboratory instrumentation often requires significant programming expertise, creating a barrier for researchers lacking computational skills. This work explores the potential of large language models (LLMs), such as…

Artificial Intelligence · Computer Science 2026-04-07 Yong Xie , Kexin He , Andres Castellanos-Gomez

The past decade has been transformative for mental health research and practice. The ability to harness large repositories of data, whether from electronic health records (EHR), mobile devices, or social media, has revealed a potential for…

Computation and Language · Computer Science 2023-11-28 Munmun De Choudhury , Sachin R. Pendse , Neha Kumar

One of the major barriers to using large language models (LLMs) in medicine is the perception they use uninterpretable methods to make clinical decisions that are inherently different from the cognitive processes of clinicians. In this…

Computation and Language · Computer Science 2023-08-15 Thomas Savage , Ashwin Nayak , Robert Gallo , Ekanath Rangan , Jonathan H Chen

Multimodal Large Language Models (MLLMs) have shown success in various general image processing tasks, yet their application in medical imaging is nascent, lacking tailored models. This study investigates the potential of MLLMs in improving…

Computer Vision and Pattern Recognition · Computer Science 2024-05-13 Ling Yang , Zhanyu Wang , Zhenghao Chen , Xinyu Liang , Luping Zhou

Generative Large Language Models (gLLMs), such as ChatGPT, are increasingly being used in communication research for content analysis. Studies show that gLLMs can outperform both crowd workers and trained coders, such as research…

Artificial Intelligence · Computer Science 2025-10-29 Daria Kravets-Meinke , Hannah Schmid-Petri , Sonja Niemann , Ute Schmid

The complexity and heterogeneity of data in many real-world applications pose significant challenges for traditional machine learning and signal processing techniques. For instance, in medicine, effective analysis of diverse physiological…

Machine Learning · Computer Science 2024-08-16 Nimeesha Chan , Felix Parker , William Bennett , Tianyi Wu , Mung Yao Jia , James Fackler , Kimia Ghobadi

Large Language Models (LLMs) have revo lutionized natural language processing Natural Language Processing (NLP), with Chat Generative Pre-trained Transformer (ChatGPT) standing out as a notable exampledue to its advanced capabilities and…

Computation and Language · Computer Science 2025-03-25 Azim Akhtarshenas , Afshin Dini , Navid Ayoobi

Generative Large Language Models (LLMs) hold significant promise in healthcare, demonstrating capabilities such as passing medical licensing exams and providing clinical knowledge. However, their current use as information retrieval tools…

Following the impressive development of LLMs, vision-language alignment in LLMs is actively being researched to enable multimodal reasoning and visual IO. This direction of research is particularly relevant to medical imaging because…

Computer Vision and Pattern Recognition · Computer Science 2024-03-19 Suhyeon Lee , Won Jun Kim , Jinho Chang , Jong Chul Ye

Writing radiology reports from medical images requires a high level of domain expertise. It is time-consuming even for trained radiologists and can be error-prone for inexperienced radiologists. It would be appealing to automate this task…

Computer Vision and Pattern Recognition · Computer Science 2023-12-05 Yuzhe Lu , Sungmin Hong , Yash Shah , Panpan Xu

Effective patient-provider communication is crucial in clinical care, directly impacting patient outcomes and quality of life. Traditional evaluation methods, such as human ratings, patient feedback, and provider self-assessments, are often…

Computation and Language · Computer Science 2024-09-25 Zhiyuan Wang , Fangxu Yuan , Virginia LeBaron , Tabor Flickinger , Laura E. Barnes

Medical large vision-language models (LVLMs) have demonstrated promising performance across various single-image question answering (QA) benchmarks, yet their capability in processing multi-image clinical scenarios remains underexplored.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Xikai Yang , Juzheng Miao , Yuchen Yuan , Jiaze Wang , Qi Dou , Jinpeng Li , Pheng-Ann Heng

Large Language Models (LLMs) like GPT-4, MedPaLM-2, and Med-Gemini achieve performance competitively with human experts across various medical benchmarks. However, they still face challenges in making professional diagnoses akin to…

Computation and Language · Computer Science 2024-08-23 Xiaohan Wang , Xiaoyan Yang , Yuqi Zhu , Yue Shen , Jian Wang , Peng Wei , Lei Liang , Jinjie Gu , Huajun Chen , Ningyu Zhang

With the increasing application of large language models (LLMs) in the medical domain, evaluating these models' performance using benchmark datasets has become crucial. This paper presents a comprehensive survey of various benchmark…

Large Language Models (LLMs) have been widely applied in various professional fields. By fine-tuning the models using domain specific question and answer datasets, the professional domain knowledge and Q\&A abilities of these models have…

Computation and Language · Computer Science 2024-07-17 Qimin Yang , Rongsheng Wang , Jiexin Chen , Runqi Su , Tao Tan

The disruptive technology provided by large-scale pre-trained language models (LLMs) such as ChatGPT or GPT-4 has received significant attention in several application domains, often with an emphasis on high-level opportunities and…

Human-Computer Interaction · Computer Science 2023-06-27 Philippe J. Giabbanelli

The diagnosis of most mental disorders, including psychiatric evaluations, primarily depends on dialogues between psychiatrists and patients. This subjective process can lead to variability in diagnoses across clinicians and patients,…

Artificial Intelligence · Computer Science 2025-10-30 Eranga Bandara , Ross Gore , Atmaram Yarlagadda , Anita H. Clayton , Preston Samuel , Christopher K. Rhea , Sachin Shetty