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Digital health tools have the potential to significantly improve the delivery of healthcare services. However, their adoption remains comparatively limited due, in part, to challenges surrounding usability and trust. Large Language Models…

Computation and Language · Computer Science 2024-03-01 Fergus Imrie , Paulius Rauba , Mihaela van der Schaar

In this paper, we aimed to provide a review and tutorial for researchers in the field of medical imaging using language models to improve their tasks at hand. We began by providing an overview of the history and concepts of language models,…

Computer Vision and Pattern Recognition · Computer Science 2023-04-12 Mingzhe Hu , Shaoyan Pan , Yuheng Li , Xiaofeng Yang

Recent advancements in Natural Language Processing (NLP), particularly in Large Language Models (LLMs), associated with deep learning-based computer vision techniques, have shown substantial potential for automating a variety of tasks. One…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Lucas Prado Osco , Eduardo Lopes de Lemos , Wesley Nunes Gonçalves , Ana Paula Marques Ramos , José Marcato Junior

ChatGPT has drawn considerable attention from both the general public and domain experts with its remarkable text generation capabilities. This has subsequently led to the emergence of diverse applications in the field of biomedicine and…

The primary aim of this research was to address the limitations observed in the medical knowledge of prevalent large language models (LLMs) such as ChatGPT, by creating a specialized language model with enhanced accuracy in medical advice.…

Computation and Language · Computer Science 2023-06-27 Yunxiang Li , Zihan Li , Kai Zhang , Ruilong Dan , Steve Jiang , You Zhang

Medical image analysis is essential in modern healthcare. Deep learning has redirected research focus toward complex medical multimodal tasks, including report generation and visual question answering. Traditional task-specific models often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Yiming Shi , Shaoshuai Yang , Xun Zhu , Haoyu Wang , Xiangling Fu , Miao Li , Ji Wu

Medical imaging is an essential tool for diagnosing various healthcare diseases and conditions. However, analyzing medical images is a complex and time-consuming task that requires expertise and experience. This article aims to design a…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 Ayyub Alzahem , Shahid Latif , Wadii Boulila , Anis Koubaa

Large Language Models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence (AI) technology which is rapidly evolving and promises to aid in medical diagnosis either by assisting doctors or by simulating a doctor's…

This paper explores the advancements and applications of large-scale models in the medical field, with a particular focus on Medical Large Models (MedLMs). These models, encompassing Large Language Models (LLMs), Vision Models, 3D Large…

Artificial Intelligence · Computer Science 2025-10-08 YunHe Su , Zhengyang Lu , Junhui Liu , Ke Pang , Haoran Dai , Sa Liu , Yuxin Jia , Lujia Ge , Jing-min Yang

The ChatGPT, a lite and conversational variant of Generative Pretrained Transformer 4 (GPT-4) developed by OpenAI, is one of the milestone Large Language Models (LLMs) with billions of parameters. LLMs have stirred up much interest among…

Computation and Language · Computer Science 2023-08-01 Hanyao Huang , Ou Zheng , Dongdong Wang , Jiayi Yin , Zijin Wang , Shengxuan Ding , Heng Yin , Chuan Xu , Renjie Yang , Qian Zheng , Bing Shi

Background: Large Language Models (LLMs) are transforming artificial intelligence applications in healthcare due to their ability to understand, generate, and summarize complex medical text. They offer valuable support to clinicians,…

Computation and Language · Computer Science 2026-04-14 Subin Santhosh , Farwa Abbas , Hussain Ahmad , Claudia Szabo

The development of large language models (LLMs) has brought unprecedented possibilities for artificial intelligence (AI) based medical diagnosis. However, the application perspective of LLMs in real diagnostic scenarios is still unclear…

Computation and Language · Computer Science 2024-05-21 Zhoujian Sun , Cheng Luo , Ziyi Liu , Zhengxing Huang

Addressing the complexity of accurately classifying International Classification of Diseases (ICD) codes from medical discharge summaries is challenging due to the intricate nature of medical documentation. This paper explores the use of…

Machine Learning · Computer Science 2024-11-12 Zeyd Boukhers , AmeerAli Khan , Qusai Ramadan , Cong Yang

Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi

3D medical image analysis is of great importance in disease diagnosis and treatment. Recently, multimodal large language models (MLLMs) have exhibited robust perceptual capacity, strong cross-modal alignment, and promising generalizability.…

Computer Vision and Pattern Recognition · Computer Science 2026-04-14 Yang Yu , Dunyuan Xu , Yaoqian Li , Xiaomeng Li , Jinpeng Li , Pheng-Ann Heng

The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods. In this paper, we propose MDNet to establish a direct multimodal…

Computer Vision and Pattern Recognition · Computer Science 2017-07-11 Zizhao Zhang , Yuanpu Xie , Fuyong Xing , Mason McGough , Lin Yang

Medical knowledge graphs (KGs) are essential for clinical decision support and biomedical research, yet they often exhibit incompleteness due to knowledge gaps and structural limitations in medical coding systems. This issue is particularly…

Computation and Language · Computer Science 2025-04-01 Xinyu Yao , Aditya Sannabhadti , Holly Wiberg , Karmel S. Shehadeh , Rema Padman

In recent years, large language models (LLMs) have demonstrated remarkable potential across various medical applications. Building on this foundation, multimodal large language models (MLLMs) integrate LLMs with visual models to process…

Computation and Language · Computer Science 2025-03-11 Xiaoyi Liang , Mouxiao Bian , Moxin Chen , Lihao Liu , Junjun He , Jie Xu , Lin Li

Artificial intelligence has dramatically reshaped our interaction with digital technologies, ushering in an era where advancements in AI algorithms and Large Language Models (LLMs) have natural language processing (NLP) systems like…

Computation and Language · Computer Science 2024-06-12 Masoumeh Farhadi Nia , Mohsen Ahmadi , Elyas Irankhah

The large-scale development of large language models (LLMs) in medical contexts, such as diagnostic assistance and treatment recommendations, necessitates that these models possess accurate medical knowledge and deliver traceable…

Artificial Intelligence · Computer Science 2025-08-12 Qiyuan Li , Haijiang Liu , Caicai Guo , Chao Gao , Deyu Chen , Meng Wang , Feng Gao , Frank van Harmelen , Jinguang Gu