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Diffusion models are a special type of generative model, capable of synthesising new data from a learnt distribution. We introduce DISPR, a diffusion-based model for solving the inverse problem of three-dimensional (3D) cell shape…

Computer Vision and Pattern Recognition · Computer Science 2023-03-15 Dominik J. E. Waibel , Ernst Röell , Bastian Rieck , Raja Giryes , Carsten Marr

In recent years, diffusion models trained on equilibrium molecular distributions have proven effective for sampling biomolecules. Beyond direct sampling, the score of such a model can also be used to derive the forces that act on molecular…

Machine Learning · Computer Science 2026-01-15 Michael Plainer , Hao Wu , Leon Klein , Stephan Günnemann , Frank Noé

Recent developments in generative modeling have utilized score-based methods coupled with stochastic differential equations to sample from complex probability distributions. However, these and other performant sampling methods generally…

Machine Learning · Computer Science 2025-06-03 Bryan Riel , Tobias Bischoff

Existing diffusion-based methods for inverse problems sample from the posterior using score functions and accept the generated random samples as solutions. In applications that posterior mean is preferred, we have to generate multiple…

Machine Learning · Computer Science 2024-10-10 Zhipeng Xue , Penghao Cai , Xiaojun Yuan , Xiqi Gao

Denoising diffusion models (DDMs) offer a flexible framework for sampling from high dimensional data distributions. DDMs generate a path of probability distributions interpolating between a reference Gaussian distribution and a data…

Machine Learning · Statistics 2024-12-12 Christopher Williams , Andrew Campbell , Arnaud Doucet , Saifuddin Syed

Existing core-set selection methods predominantly rely on heuristic scoring signals such as training dynamics or model uncertainty, lacking explicit modeling of data likelihood. This omission may hinder the constructed subset from capturing…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Mingyang Chen , Jiawei Du , Bo Huang , Yi Wang , Xiaobo Zhang , Wei Wang

Since their initial introduction, score-based diffusion models (SDMs) have been successfully applied to solve a variety of linear inverse problems in finite-dimensional vector spaces due to their ability to efficiently approximate the…

Machine Learning · Statistics 2023-10-31 Lorenzo Baldassari , Ali Siahkoohi , Josselin Garnier , Knut Solna , Maarten V. de Hoop

With the development of audio playback devices and fast data transmission, the demand for high sound quality is rising for both entertainment and communications. In this quest for better sound quality, challenges emerge from distortions and…

Audio and Speech Processing · Electrical Eng. & Systems 2024-11-12 Jean-Marie Lemercier , Julius Richter , Simon Welker , Eloi Moliner , Vesa Välimäki , Timo Gerkmann

Real-world datasets are inherently heterogeneous, yet how per-class structural differences and sampling imbalance shape the training dynamics of diffusion models-and potentially exacerbate disparities-remains poorly understood. While models…

Machine Learning · Statistics 2026-05-08 Flavio Nicoletti , Chenxiao Ma , Enrico Ventura , Luca Saglietti , Stefano Sarao Mannelli

This paper presents a class of new algorithms for distributed statistical estimation that exploit divide-and-conquer approach. We show that one of the key benefits of the divide-and-conquer strategy is robustness, an important…

Statistics Theory · Mathematics 2018-08-29 Stanislav Minsker , Nate Strawn

The local intrinsic dimension (LID) of data is a fundamental quantity in signal processing and learning theory, but quantifying the LID of high-dimensional, complex data has been a historically challenging task. Recent works have discovered…

Machine Learning · Computer Science 2025-11-27 Eric Yeats , Aaron Jacobson , Darryl Hannan , Yiran Jia , Timothy Doster , Henry Kvinge , Scott Mahan

Diffusion models excel in content generation by implicitly learning the data manifold, yet they lack a practical method to leverage this manifold - unlike other deep generative models equipped with latent spaces. This paper introduces a…

Computer Vision and Pattern Recognition · Computer Science 2025-04-30 Shinnosuke Saito , Takashi Matsubara

Generative diffusion models synthesize new samples by reversing a diffusive process that converts a given data set to generic noise. This is accomplished by training a neural network to match the gradient of the log of the probability…

Machine Learning · Computer Science 2023-10-11 Akhil Premkumar

In this work, we investigate an intriguing and prevalent phenomenon of diffusion models which we term as "consistent model reproducibility": given the same starting noise input and a deterministic sampler, different diffusion models often…

Machine Learning · Computer Science 2024-06-11 Huijie Zhang , Jinfan Zhou , Yifu Lu , Minzhe Guo , Peng Wang , Liyue Shen , Qing Qu

Diffusion models offer stable training and state-of-the-art performance for deep generative modeling tasks. Here, we consider their use in the context of multivariate subsurface modeling and probabilistic inversion. We first demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-01-28 Roberto Miele , Niklas Linde

How diffusion models generalize beyond their training set is not known, and is somewhat mysterious given two facts: the optimum of the denoising score matching (DSM) objective usually used to train diffusion models is the score function of…

Machine Learning · Computer Science 2025-04-18 John J. Vastola

Popularized by their strong image generation performance, diffusion and related methods for generative modeling have found widespread success in visual media applications. In particular, diffusion methods have enabled new approaches to data…

Image and Video Processing · Electrical Eng. & Systems 2026-01-28 Yibo Yang , Stephan Mandt

Diffusion models learn to restore noisy data, which is corrupted with different levels of noise, by optimizing the weighted sum of the corresponding loss terms, i.e., denoising score matching loss. In this paper, we show that restoring data…

Computer Vision and Pattern Recognition · Computer Science 2022-04-04 Jooyoung Choi , Jungbeom Lee , Chaehun Shin , Sungwon Kim , Hyunwoo Kim , Sungroh Yoon

Score-based generative modeling (SGM) has grown to be a hugely successful method for learning to generate samples from complex data distributions such as that of images and audio. It is based on evolving an SDE that transforms white noise…

Machine Learning · Computer Science 2022-10-04 Holden Lee , Jianfeng Lu , Yixin Tan

Generative AI models, such as score-based diffusion models, have recently advanced the field of computational materials science by enabling the generation of new materials with desired properties. In addition, these models could also be…

Materials Science · Physics 2026-01-06 Timo Reents , Arianna Cantarella , Marnik Bercx , Pietro Bonfà , Giovanni Pizzi
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