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Incorporating artificial intelligence (AI) into digital pathology offers promising prospects for automating and enhancing tasks such as image analysis and diagnostic processes. However, the diversity of tissue samples and the necessity for…

Image and Video Processing · Electrical Eng. & Systems 2024-12-04 Nati Daniel , May Nathan , Eden Azeroual , Yael Fisher , Yonatan Savir

An optical microscopic examination of thinly cut stained tissue on glass slides prepared from a FFPE tissue blocks is the gold standard for tissue diagnostics. In addition, the diagnostic abilities and expertise of any pathologist is…

In semantic image synthesis the state of the art is dominated by methods that use customized variants of the SPatially-Adaptive DE-normalization (SPADE) layers, which allow for good visual generation quality and editing versatility. By…

Computer Vision and Pattern Recognition · Computer Science 2025-03-31 Tomaso Fontanini , Claudio Ferrari , Giuseppe Lisanti , Massimo Bertozzi , Andrea Prati

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Semantic image synthesis (SIS) refers to the problem of generating realistic imagery given a semantic segmentation mask that defines the spatial layout of object classes. Most of the approaches in the literature, other than the quality of…

Computer Vision and Pattern Recognition · Computer Science 2023-07-12 Tomaso Fontanini , Claudio Ferrari , Massimo Bertozzi , Andrea Prati

Semantic image synthesis (SIS) aims to generate realistic images that match given semantic masks. Despite recent advances allowing high-quality results and precise spatial control, they require a massive semantic segmentation dataset for…

Computer Vision and Pattern Recognition · Computer Science 2024-02-23 Jungwoo Chae , Hyunin Cho , Sooyeon Go , Kyungmook Choi , Youngjung Uh

Generative models have been applied in the medical imaging domain for various image recognition and synthesis tasks. However, a more controllable and interpretable image synthesis model is still lacking yet necessary for important…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Jiarong Ye , Yuan Xue , Peter Liu , Richard Zaino , Keith Cheng , Xiaolei Huang

The rapid advancement of Artificial Intelligence (AI) in biomedical imaging and radiotherapy is hindered by the limited availability of large imaging data repositories. With recent research and improvements in denoising diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Rowan Bradbury , Katherine A. Vallis , Bartlomiej W. Papiez

Artificial intelligence and machine learning techniques have the promise to revolutionize the field of digital pathology. However, these models demand considerable amounts of data, while the availability of unbiased training data is…

Image and Video Processing · Electrical Eng. & Systems 2023-02-14 Nati Daniel , Eliel Aknin , Ariel Larey , Yoni Peretz , Guy Sela , Yael Fisher , Yonatan Savir

The development of robust deep learning models for breast ultrasound (BUS) image analysis is significantly constrained by the scarcity of expert-annotated data. To address this limitation, we propose a clinically controllable generative…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Haoyu Pan , Hongxin Lin , Zetian Feng , Chuxuan Lin , Junyang Mo , Chu Zhang , Zijian Wu , Yi Wang , Qingqing Zheng

The development of clinical-grade artificial intelligence in pathology is limited by the scarcity of diverse, high-quality annotated datasets. Generative models offer a potential solution but suffer from semantic instability and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-17 Xianchao Guan , Zhiyuan Fan , Yifeng Wang , Fuqiang Chen , Yanjiang Zhou , Zengyang Che , Hongxue Meng , Xin Li , Yaowei Wang , Hongpeng Wang , Min Zhang , Heng Tao Shen , Zheng Zhang , Yongbing Zhang

Diffusion-based generative models have shown promise in synthesizing histopathology images to address data scarcity caused by privacy constraints. Diagnostic text reports provide high-level semantic descriptions, and masks offer…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Mahesh Bhosale , Abdul Wasi , Yuanhao Zhai , Yunjie Tian , Samuel Border , Nan Xi , Pinaki Sarder , Junsong Yuan , David Doermann , Xuan Gong

Semantic segmentation of medical images is pivotal in applications like disease diagnosis and treatment planning. While deep learning has excelled in automating this task, a major hurdle is the need for numerous annotated segmentation…

Image and Video Processing · Electrical Eng. & Systems 2024-09-02 Li Zhang , Basu Jindal , Ahmed Alaa , Robert Weinreb , David Wilson , Eran Segal , James Zou , Pengtao Xie

Recent advancements in conditional Generative Adversarial Networks (cGANs) have shown promises in label guided image synthesis. Semantic masks, such as sketches and label maps, are another intuitive and effective form of guidance in image…

Computer Vision and Pattern Recognition · Computer Science 2019-07-04 Yinhao Ren , Zhe Zhu , Yingzhou Li , Joseph Lo

The need for large amounts of training and validation data is a huge concern in scaling AI algorithms for autonomous driving. Semantic Image Synthesis (SIS), or label-to-image translation, promises to address this issue by translating…

Computer Vision and Pattern Recognition · Computer Science 2023-05-18 George Eskandar , Diandian Guo , Karim Guirguis , Bin Yang

Tissue semantic segmentation is one of the key tasks in computational pathology. To avoid the expensive and laborious acquisition of pixel-level annotations, a wide range of studies attempt to adopt the class activation map (CAM), a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-31 Zijie Fang , Yifeng Wang , Peizhang Xie , Zhi Wang , Yongbing Zhang

Semantic image synthesis, i.e., generating images from user-provided semantic label maps, is an important conditional image generation task as it allows to control both the content as well as the spatial layout of generated images. Although…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Tariq Berrada , Jakob Verbeek , Camille Couprie , Karteek Alahari

Dichotomous Image Segmentation (DIS) tasks require highly precise annotations, and traditional dataset creation methods are labor intensive, costly, and require extensive domain expertise. Although using synthetic data for DIS is a…

Computer Vision and Pattern Recognition · Computer Science 2024-12-30 Haotian Qian , YD Chen , Shengtao Lou , Fahad Shahbaz Khan , Xiaogang Jin , Deng-Ping Fan

Synthetic generation of three-dimensional cell models from histopathological images aims to enhance understanding of cell mutation, and progression of cancer, necessary for clinical assessment and optimal treatment. Classical reconstruction…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Yoav Alon , Xiang Yu , Huiyu Zhou

Histopathological image segmentation is a laborious and time-intensive task, often requiring analysis from experienced pathologists for accurate examinations. To reduce this burden, supervised machine-learning approaches have been adopted…

Computer Vision and Pattern Recognition · Computer Science 2024-09-12 Vishnuvardhan Purma , Suhas Srinath , Seshan Srirangarajan , Aanchal Kakkar , Prathosh A. P
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