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Chromosome enumeration is an essential but tedious procedure in karyotyping analysis. To automate the enumeration process, we develop a chromosome enumeration framework, DeepACEv2, based on the region based object detection scheme. The…

Computer Vision and Pattern Recognition · Computer Science 2020-07-21 Li Xiao , Chunlong Luo , Tianqi Yu , Yufan Luo , Manqing Wang , Fuhai Yu , Yinhao Li , Chan Tian , Jie Qiao

A main task in cryo-electron microscopy single particle reconstruction is to find a three-dimensional model of a molecule given a set of its randomly oriented and positioned noisy projection-images. In this work, we propose an algorithm for…

Computational Physics · Physics 2022-11-11 Adi Shasha Geva , Yoel Shkolnisky

Medical images acquired from standardized protocols show consistent macroscopic or microscopic anatomical structures, and these structures consist of composable/decomposable organs and tissues, but existing self-supervised learning (SSL)…

Computer Vision and Pattern Recognition · Computer Science 2025-01-20 Ziyu Zhou , Haozhe Luo , Mohammad Reza Hosseinzadeh Taher , Jiaxuan Pang , Xiaowei Ding , Michael Gotway , Jianming Liang

Cryo-electron microscopy is a revolutionary technique that can provide 3D density maps at near-atomic resolution. However, map validation is still an open issue in the field. Despite several efforts from the community, it is possible to…

Biological Physics · Physics 2019-08-06 Sebastian Ortiz , Luka Stanisic , Boris A Rodriguez , Markus Rampp , Gerhard Hummer , Pilar Cossio

In this work we propose an autoencoder based framework for simultaneous reconstruction and classification of biomedical signals. Previously these two tasks, reconstruction and classification were treated as separate problems. This is the…

Signal Processing · Electrical Eng. & Systems 2019-12-30 Anupriya Gogna , Angshul Majumdar , Rabab Ward

Autoencoders are composed of coding and decoding units, hence they hold the inherent potential of high-performance data compression and signal compressed sensing. The main disadvantages of current autoencoders comprise the following several…

Machine Learning · Computer Science 2022-07-28 Honggui Li , Dimitri Galayko , Maria Trocan , Mohamad Sawan

Cryo-Electron Tomography (cryo-ET) is a new 3D imaging technique with unprecedented potential for resolving submicron structural detail. Existing volume visualization methods, however, cannot cope with its very low signal-to-noise ratio. In…

Quantitative Methods · Quantitative Biology 2026-03-27 Ngan Nguyen , Ciril Bohak , Dominik Engel , Peter Mindek , Ondřej Strnad , Peter Wonka , Sai Li , Timo Ropinski , Ivan Viola

Unmanned underwater image analysis for marine monitoring faces two key challenges: (i) degraded image quality due to light attenuation and (ii) hardware storage constraints limiting high-resolution image collection. Existing methods…

Computer Vision and Pattern Recognition · Computer Science 2024-11-25 Rita Pucci , Niki Martinel

We demonstrate a multi-beam scanning transmission electron microscopy (STEM) imaging that integrates down-sampling with super-resolution image reconstruction via a compressive sensing framework. A custom condenser aperture with six randomly…

Instrumentation and Detectors · Physics 2026-03-19 Akira Yasuhara , Takumi Sannomiya , Ryoichi Horisaki

Autoencoders are a class of artificial neural networks which have gained a lot of attention in the recent past. Using the encoder block of an autoencoder the input image can be compressed into a meaningful representation. Then a decoder is…

Computer Vision and Pattern Recognition · Computer Science 2020-12-11 Sayan Nag

Ptychography is a computational imaging technique using multiple, overlapping, coherently illuminated snapshots to achieve nanometer resolution by solving a nonlinear phase-field recovery problem. Ptychography is vital for imaging of…

Image and Video Processing · Electrical Eng. & Systems 2021-12-10 Qiuchen Zhai , Brendt Wohlberg , Gregery T. Buzzard , Charles A. Bouman

While Computerized Tomography (CT) images can help detect disease such as Covid-19, regular CT machines are large and expensive. Cheaper and more portable machines suffer from errors in geometry acquisition that downgrades CT image quality.…

Image and Video Processing · Electrical Eng. & Systems 2021-08-03 Peijian Ding

Cryo-electron microscopy (cryo-EM) is a powerful technique in structural biology and drug discovery, enabling the study of biomolecules at high resolution. Significant advancements by structural biologists using cryo-EM have led to the…

Biomolecules · Quantitative Biology 2024-12-05 Yi Zhou , Yilai Li , Jing Yuan , Quanquan Gu

Existing Masked Image Modeling (MIM) depends on a spatial patch-based masking-reconstruction strategy to perceive objects'features from unlabeled images, which may face two limitations when applied to chest CT: 1) inefficient feature…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Jie Zheng , Ru Wen , Haiqin Hu , Lina Wei , Kui Su , Wei Chen , Chen Liu , Jun Wang

X-ray polarization is a powerful tool for unveiling the anisotropic characteristics of high-energy celestial objects. We present a novel imaging reconstruction method designed for hard X-ray polarimeters employing a Si CMOS sensor and coded…

Instrumentation and Methods for Astrophysics · Physics 2024-07-09 Tsubasa Tamba , Hirokazu Odaka , Taihei Watanabe , Toshiya Iwata , Tomoaki Kasuga , Atsushi Tanimoto , Satoshi Takashima , Masahiro Ichihashi , Hiromasa Suzuki , Aya Bamba

Constructing reduced-order models (ROMs) capable of efficiently predicting the evolution of high-dimensional, parametric systems is crucial in many applications in engineering and applied sciences. A popular class of projection-based ROMs…

Machine Learning · Computer Science 2026-03-17 Nicolò Botteghi , Silke Glas , Christoph Brune

Autoregressive models for 3D mesh generation suffer from a fundamental limitation: they flatten meshes into long vertex-coordinate sequences. This results in prohibitive computational costs, hindering the efficient synthesis of…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Hanxiao Wang , Yuan-Chen Guo , Ying-Tian Liu , Zi-Xin Zou , Biao Zhang , Weize Quan , Ding Liang , Yan-Pei Cao , Dong-Ming Yan

Electrocardiogram (ECG) diagnosis remains challenging due to limited labeled data and the need to capture subtle yet clinically meaningful variations in rhythm and morphology. We present CREMA (Contrastive Regularized Masked Autoencoder), a…

Machine Learning · Computer Science 2025-08-22 Junho Song , Jong-Hwan Jang , DongGyun Hong , Joon-myoung Kwon , Yong-Yeon Jo

Autoencoders (AE) provide a useful method for nonlinear dimensionality reduction but are ill-suited for low data regimes. Conversely, Principal Component Analysis (PCA) is data-efficient but is limited to linear dimensionality reduction,…

Deep learning models for 12-lead electrocardiogram (ECG) analysis achieve high diagnostic performance but lack the intuitive interpretability required for clinical integration. Standard feature attribution methods are limited by the…

Image and Video Processing · Electrical Eng. & Systems 2026-05-01 Karol Dobiczek , Maciej Mozolewski , Szymon Bobek , Michał Szafarczyk , Peter van Dam , Grzegorz J. Nalepa