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The indirect effect of an exposure on an outcome through an intermediate variable can be identified by a product of two regression coefficients under certain causal and regression modeling assumptions. In this context, the null hypothesis…

Statistics Theory · Mathematics 2025-07-23 Caleb H. Miles , Antoine Chambaz

Large-scale testing is crucial in pandemic containment, but resources are often prohibitively constrained. We study the optimal application of pooled testing for populations that are heterogeneous with respect to an individual's infection…

Computer Science and Game Theory · Computer Science 2023-09-22 Simon Finster , Michelle González Amador , Edwin Lock , Francisco Marmolejo-Cossío , Evi Micha , Ariel D. Procaccia

We analyzed the effect of the deviation of the exact distribution of the p-values from the uniform distribution on the Kolmogorov-Smirnov (K-S) test that was implemented as the second-level randomness test. We derived an inequality that…

Methodology · Statistics 2021-10-18 Akihiro Yamaguchi , Asaki Saito

A fundamental challenge in comparing two survival distributions with right censored data is the selection of an appropriate nonparametric test, as the power of standard tests like the Log rank and Wilcoxon is highly dependent on the often…

Methodology · Statistics 2025-10-09 Abid Hussain , Touqeer Ahmad

Standard ANOVA is among the most widely used tests in the life sciences and beyond. Several alternatives are proposed to provide simultaneous confidence intervals, ensure tight control of FWER, be robust to variance heterogeneity, avoid…

Methodology · Statistics 2022-06-01 Ludwig A. Hothorn

Thanks to its favorable properties, the multivariate normal distribution is still largely employed for modeling phenomena in various scientific fields. However, when the number of components $p$ is of the same asymptotic order as the sample…

Statistics Theory · Mathematics 2022-11-17 Caizhu Huang , Claudia Di Caterina , Nicola Sartori

Identifying the most powerful test in multiple hypothesis testing under strong family-wise error rate (FWER) control is a fundamental problem in statistical methodology. State-of-the-art approaches formulate this as a constrained…

Methodology · Statistics 2025-12-17 Prasanjit Dubey , Xiaoming Huo

In Bayesian accelerated life testing, the most used tool for model comparison is the deviance information criterion. An alternative and more formal approach is to use Bayes factors to compare models. However, Bayesian accelerated life…

Methodology · Statistics 2026-01-16 Neill Smit , Lizanne Raubenheimer

Vovk (2015) introduced cross-conformal prediction, a modification of split conformal designed to improve the width of prediction sets. The method, when trained with a miscoverage rate equal to $\alpha$ and $n \gg K$, ensures a marginal…

Machine Learning · Statistics 2025-05-22 Matteo Gasparin , Aaditya Ramdas

Inverse probability weighting (IPW) is widely used in many areas when data are subject to unrepresentativeness, missingness, or selection bias. An inevitable challenge with the use of IPW is that the IPW estimator can be remarkably unstable…

Methodology · Statistics 2021-11-29 Yukun Liu , Yan Fan

The question of testing for equality in distribution between two linear models, each consisting of sums of distinct discrete independent random variables with unequal numbers of observations, has emerged from the biological research. In…

Statistics Theory · Mathematics 2020-09-01 Giulio Prevedello , Ken R. Duffy

The basic motivation and primary goal of this paper is a qualitative evaluation of the performance of a new weighted statistic for a nonparametric test for stochastic dominance based on two samples, which was introduced in Ledwina and…

Statistics Theory · Mathematics 2018-06-07 Inglot Tadeusz , Ledwina Teresa , Ćmiel Bogdan

We propose an adjusted likelihood ratio test of two-factor separability (Kronecker product structure) for unbalanced multivariate repeated measures data. Here we address the particular case where the within subject correlation is believed…

Methodology · Statistics 2011-02-02 Sean L. Simpson

Testing the association between a phenotype and many genetic variants from case-control data is essential in genome-wide association study (GWAS). This is a challenging task as many such variants are correlated or non-informative.…

Methodology · Statistics 2016-01-25 Zhendong Huang , Davide Ferrari , Guoqi Qian

In this paper, a new and convenient $\chi^2$ wald test based on MCMC outputs is proposed for hypothesis testing. The new statistic can be explained as MCMC version of Wald test and has several important advantages that make it very…

Econometrics · Economics 2018-01-04 Yong Li , Xiaobin Liu , Jun Yu , Tao Zeng

In this paper, we give an explanation to the failure of two likelihood ratio procedures for testing about covariance matrices from Gaussian populations when the dimension is large compared to the sample size. Next, using recent central…

Statistics Theory · Mathematics 2011-09-09 Zhidong Bai , Dandan Jiang , Jian-feng Yao , Shurong Zheng

We study the detection capability of the weak-value amplification on the basis of the statistical hypothesis testing. We propose a reasonable testing method in the physical and statistical senses to find that the weak measurement with the…

Quantum Physics · Physics 2015-08-17 Yuki Susa , Saki Tanaka

Kurtosis minus squared skewness is bounded from below by 1, but for unimodal distributions this parameter is bounded by 189/125. In some applications it is natural to compare distributions by comparing their kurtosis-minus-squared-skewness…

Statistics Theory · Mathematics 2023-12-12 Chris A. J. Klaassen , Bert van Es

High-throughput sequencing technology allows us to test the compositional difference of bacteria in different populations. One important feature of human microbiome data is that it often includes a large number of zeros. Such data can be…

Methodology · Statistics 2022-08-23 Wanjie Wang , Eric Z. Chen , Hongzhe Li

Alerting experience with a well-acknowledged safety analysis code initiated the authors to pay attention to safety issues of complex systems. Their first concern was the statistical characteristics of such a code. We point out a remarkable…

Data Analysis, Statistics and Probability · Physics 2007-05-23 L. Pal , M. Makai