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Phase separation of various materials has been studied for one and a half centuries. In the last two decades, phase separation of proteins and nucleic acids has received enormous attention, due its relevance to cellular functions. However,…

Soft Condensed Matter · Physics 2026-05-28 Huan-Xiang Zhou

The separation of substances into different phases is ubiquitous in nature and important scientifically and technologically. This phenomenon may become drastically different if the species involved, whether molecules or supramolecular…

Microphase separation in polymeric systems provides a bottom-up strategy to fabricate nanostructures. Polymers that are reported to undergo microphase separation usually include block copolymers or polyelectrolytes. Neutral homopolymers,…

Soft Condensed Matter · Physics 2022-09-26 Xian Kong , Jian Qin

We develop a lattice-based Monte Carlo simulation method for charged mixtures capable of treating dielectric heterogeneities. Using this method, we study oil-water mixtures containing an antagonistic salt, with hydrophilic cations and…

Soft Condensed Matter · Physics 2017-11-29 Nikos Tasios , Sela Samin , René van Roij , Marjolein Dijkstra

A theory for sequence dependent liquid-liquid phase separation (LLPS) of intrinsically disordered proteins (IDPs) in the study of biomolecular condensates is formulated by extending the random phase approximation (RPA) and field-theoretic…

Biomolecules · Quantitative Biology 2022-11-28 Jonas Wessén , Suman Das , Tanmoy Pal , Hue Sun Chan

Lithium halides with the general formula Li$_x$M$_y$X$_6$, where M indicates transition metal ions and X halide anions are very actively studied as solid-state electrolytes, because of relatively low cost, high stability and Li…

Materials Science · Physics 2025-11-20 Davide Tisi , Sergey Pozdnyakov , Michele Ceriotti

Switching on high activity in a relatively dense system of active Janus colloids, we observe fast clustering, followed by cluster aggregation towards full phase separation. The phase separation process is however interrupted when large…

Soft Condensed Matter · Physics 2019-09-04 Marjolein N. van der Linden , Lachlan C. Alexander , Dirk G. A. L. Aarts , Olivier Dauchot

Motivated by the observations of intracellular phase separations and the wetting of cell membranes by protein droplets, we study the nonequilibrium surface wetting by Monte Carlo simulations of a lattice gas model involving particle…

Biological Physics · Physics 2022-06-23 Kyosuke Adachi , Kyogo Kawaguchi

We propose a one-dimensional model of active particles interpolating between quorum sensing models used in the study of motility-induced phase separation (MIPS) and models of congestion of traffic flow on a single-lane highway. Particles…

Statistical Mechanics · Physics 2026-01-08 Eric Bertin , Alexandre Solon

Liquid-liquid phase separation has recently emerged as an important topic in the context of cellular organization. Within this context, there are multiple poorly understood features; for instance hints of critical behavior in the plasma…

Statistical Mechanics · Physics 2024-06-25 Felix Herrmann , Burkhard Dünweg , Martin Girard

We examine the symmetry-breaking effect of fixed constellations of particles on the surface-directed spinodal decomposition of binary blends in the presence of particles whose surfaces have a preferential affinity for one of the components.…

Chemical Physics · Physics 2020-06-16 Supriyo Ghosh , Arnab Mukherjee , Raymundo Arroyave , Jack F. Douglas

A combination of cellular contractility and active phase separation in cell-matrix composites is thought to be an enabler of spatiotemporal patterning in multicellular tissues across scales, from somitogenesis to cartilage condensation. To…

Soft Condensed Matter · Physics 2022-11-21 Sifan Yin , L Mahadevan

Motility-induced phase separation (MIPS) is of great importance and has been extensively researched in overdamped systems, nevertheless, what impacts inertia will bring on kinetics of MIPS is lack of investigation. Here, we find that, not…

Soft Condensed Matter · Physics 2020-09-09 Jie Su , Huijun Jiang , Zhonghuai Hou

Understanding the mechanisms of explosions is important for minimizing devastating hazards. Due to the complexity of real chemistry, a single-step reaction mechanism is usually used for theoretical and numerical studies. The purpose of this…

Chemical Physics · Physics 2019-07-24 Mikhail Liberman , Cheng Wang , Chengeng Qian , JianNan Liu

Microscopic dynamics of complex fluids in the early stage of spinodal decomposition (SD) is strongly intertwined with the kinetics of structural evolution, which makes a quantitative characterization challenging. In this work, we use x-ray…

Phase separation, the spontaneous segregation of density, is a ubiquitous phenomenon observed across diverse physical and biological systems. Within a crowd of motile elements, active phase separation emerges from the interplay of activity…

Soft Condensed Matter · Physics 2026-01-26 Kyosuke Adachi

Wide proliferation of low temperature hydrogen fuel cell systems, a key part of the hydrogen economy, is hindered by degradation of the platinum cathode catalyst. Here, we provide a device level assessment of the molecular scale catalyst…

Complex coacervation, known as the liquid-liquid phase separation of solutions with oppositely charged polyelectrolytes, has attracted substantial interest in recent years. We study the effect of the charge regulation (CR) mechanism on the…

Soft Condensed Matter · Physics 2021-07-23 Bin Zheng , Yael Avni , David Andelman , Rudolf Podgornik

Biomolecular condensates are small droplets forming spontaneously in biological cells via phase separation. They play a role in many cellular processes, but it is unclear how cells control them. Cellular regulation often relies on…

Soft Condensed Matter · Physics 2024-03-15 Jan Kirschbaum , David Zwicker

Labyrinthine patterns arise in two-dimensional physical systems submitted to competing interactions, ranging from the fields of solid-state physics to hydrodynamics. For systems of interacting particles, labyrinthine and stripe phases were…

Soft Condensed Matter · Physics 2015-12-16 Simon Merminod , Timothee Jamin , Eric Falcon , Michael Berhanu
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