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Proteinoids -- thermal proteins -- are produced by heating amino acids to their melting point and initiation of polymerisation to produce polymeric chains. Proteinoids swell in aqueous solution into hollow microspheres. The proteinoid…

Emerging Technologies · Computer Science 2021-06-03 Andrew Adamatzky

Proteinoids are thermal proteins which form microspheres in water in presence of salt. Ensembles of proteinoid microspheres exhibit passive non-linear electrical properties and active neuron-like spiking of electrical potential. We propose…

Emerging Technologies · Computer Science 2023-06-27 Panagiotis Mougkogiannis , Andrew Adamatzky

Proteinoids (thermal proteins) are produced by heating amino acids to their melting point and initiation of polymerisation to produce polymeric chains. Amino acid-like molecules, or proteinoids, can condense at high temperatures to create…

Materials Science · Physics 2023-02-14 Panagiotis Mougkogiannis , Andrew Adamatzky

Proteinoids, or thermal proteins, are produced by heating amino acids to their melting point and initiation of polymerisation to produce polymeric chains. In aqueous solutions proteinoids swell into hollow microspheres. These microspheres…

Emerging Technologies · Computer Science 2023-03-31 Panagiotis Mougkogiannis , Andrew Adamatzky

Proteinoids are solidified gels made from poly(amino acids) based polymers that exhibit oscillatory electrical activity. It has been proposed that proteinoids are capable of performing analog computing as their electrical activity can be…

Proteinoids, also known as thermal proteins, possess a fascinating ability to generate microspheres that exhibit electrical spikes resembling the action potentials of neurons. These spiking microspheres, referred to as protoneurons, hold…

Emerging Technologies · Computer Science 2023-06-13 Panagiotis Mougkogiannis , Andrew Adamatzky

Proteins are polymers of amino acids. These macromolecules are synthesized by intracellular machines called ribosomes. Although the experimental investigation of protein synthesis has been a traditional area of research in molecular cell…

Biological Physics · Physics 2009-11-13 Aakash Basu , Debashish Chowdhury

Protein-protein interactions (protein functionalities) are mediated by water, which compacts individual proteins and promotes close and temporarily stable large-area protein-protein interfaces. Proteins are peptide chains decorated by amino…

Soft Condensed Matter · Physics 2008-02-26 J. C. Phillips

Protein folding, peptide aggregation and crystallization, as well as adsorption of molecules on soft or solid substrates have an essential feature in common: In all these processes, structure formation is guided by a collective, cooperative…

Statistical Mechanics · Physics 2009-02-12 Michael Bachmann , Wolfhard Janke

The study of protein functions attributed to the conformation and fluctuation that are ruled by both the amino acid sequence and thermodynamics, requires thermodynamic quantities given by calorimetry using thermometric techniques. The…

Biological Physics · Physics 2019-05-01 Manabu Ishino , Akio Kishigami , Hiroyuki Kudo , Jongsuck Bae , Tatsuo Nozokido

We use coarse grained molecular dynamics simulations to investigate diffusion properties of sheared lipid membranes with embedded transmembrane proteins. In membranes without proteins, we find normal in-plane diffusion of lipids in all flow…

Biological Physics · Physics 2013-09-10 Atefeh Khoshnood , Mir Abbas Jalali

Folding and aggregation of proteins, the interaction between proteins and membranes, as well as the adsorption of organic soft matter to inorganic solid substrates belong to the most interesting challenges in understanding structure and…

Soft Condensed Matter · Physics 2007-12-06 Michael Bachmann , Wolfhard Janke

Protocells are a type of synthetic cells, which, if engineered to have properties similar to a natural cell, can have immense applications in synthetic biology and bioengineering communities. Proteinoids are one of the leading contenders…

Fluid Dynamics · Physics 2022-12-13 Saksham Sharma , Panagiotis Mougoyannis , Giuseppe Tarabella , Andrew Adamatzky

It was once purported that biological systems were far too warm and wet to support quantum phenomena mainly due to thermal effects disrupting quantum coherence. However recent experimental results and theoretical analyses have shown that…

Producing food-grade soft particles with controlled structure is of interest to elucidate the structure-properties relationship in soft-particles suspensions. The aim of this work is to evaluate the ability of two elaboration processes to…

Soft Condensed Matter · Physics 2022-06-30 Alban Lacroix , Murielle Hayert , Veronique Bosc , Paul Menut

The three dimensional structure of a protein is an outcome of the interactions of its constituent amino acids in 3D space. Considering the amino acids as nodes and the interactions among them as edges we have constructed and analyzed…

Biomolecules · Quantitative Biology 2010-07-26 Dhriti Sengupta , Sudip Kundu

This paper examines the modulation of proteinoid spiking frequency in response to light. Proteinoids are proteins formed through thermal condensation of amino acids and have been found to exhibit spiking behaviour in response to various…

Emerging Technologies · Computer Science 2023-05-05 Panagiotis Mougkogiannis , Andrew Adamatzky

Proteinoids, as soft matter fluidic systems, are computational substrates that have been recently proposed for their analog computing capabilities. Such systems exhibit oscillatory electrical activity because of cationic and anionic…

Combining elastic incoherent neutron scattering experiments at different resolutions with molecular dynamics simulations, we report the observation of a protein-like dynamical transition in linear chains of Poly(N-isopropylacrylamide). We…

Soft Condensed Matter · Physics 2021-03-11 L. Tavagnacco , M. Zanatta , E. Buratti , B. Rosi , B. Frick , F. Natali , J. Ollivier , E. Chiessi , M. Bertoldo , E. Zaccarelli , A. Orecchini

Protein machines often exhibit long range interplay between different sites in order to achieve their biological tasks. We investigate and characterize the non--linear energy localization and the basic mechanisms of energy transfer in…

Biological Physics · Physics 2015-12-14 M. Caraglio , A. Imparato
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