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Meta-analysis, by synthesizing effect estimates from multiple studies conducted in diverse settings, stands at the top of the evidence hierarchy in clinical research. Yet, conventional approaches based on fixed- or random-effects models…

Trust is a crucial factor affecting the adoption of machine learning (ML) models. Qualitative studies have revealed that end-users, particularly in the medical domain, need models that can express their uncertainty in decision-making…

Machine Learning · Computer Science 2023-04-21 Andrew Houston , Georgina Cosma

[See paper for full abstract] Meta-analysis is a crucial tool for answering scientific questions. It is usually conducted on a relatively small amount of ``trusted'' data -- ideally from randomized, controlled trials -- which allow causal…

Machine Learning · Statistics 2024-07-15 Shiva Kaul , Geoffrey J. Gordon

Meta-analysis is a systematic approach for understanding a phenomenon by analyzing the results of many previously published experimental studies. It is central to deriving conclusions about the summary effect of treatments and interventions…

Computers and Society · Computer Science 2021-04-13 Lu Cheng , Dmitriy A. Katz-Rogozhnikov , Kush R. Varshney , Ioana Baldini

Meta-analysis employs statistical techniques to synthesize the results of individual studies, providing an estimate of the overall effect size for a specific outcome of interest. The direction and magnitude of this estimate, along with its…

Econometrics · Economics 2025-03-06 Amin Haghnejad , Mahboobeh Farahati

The exponential increase in academic publications has made it increasingly difficult for researchers to remain up to date and systematically synthesize knowledge scattered across vast and fragmented research domains. Literature reviews,…

Digital Libraries · Computer Science 2025-06-12 Kiran Sharmaa , Parul Khurana , Ziya Uddina

Explanations are crucial for building trustworthy AI systems, but a gap often exists between the explanations provided by models and those needed by users. To address this gap, we introduce MetaExplainer, a neuro-symbolic framework designed…

Human-Computer Interaction · Computer Science 2025-09-11 Shruthi Chari , Oshani Seneviratne , Prithwish Chakraborty , Pablo Meyer , Deborah L. McGuinness

Meta-analysis is routinely performed in many scientific disciplines. This analysis is attractive since discoveries are possible even when all the individual studies are underpowered. However, the meta-analytic discoveries may be entirely…

Methodology · Statistics 2023-05-09 Marina Bogomolov , Ruth Heller

Meta-analyses play a crucial part in empirical science, enabling researchers to synthesize evidence across studies and draw more precise and generalizable conclusions. Despite their importance, access to advanced meta-analytic methodology…

Methodology · Statistics 2025-09-15 František Bartoš , Eric-Jan Wagenmakers , Wolfgang Viechtbauer

Information exploration tasks are inherently complex, ill-structured, and involve sequences of actions usually spread over many sessions. When exploring a dataset, users tend to experiment higher degrees of uncertainty, mostly raised by…

Human-Computer Interaction · Computer Science 2022-10-03 Thiago Nunes , Daniel Schwabe

Artificial intelligence (AI) tools are being incorporated into scientific research workflows with the potential to enhance efficiency in tasks such as document analysis, question answering (Q&A), and literature search. However, system…

Artificial Intelligence · Computer Science 2026-05-13 Anthea Dathe , Kiran Hoffmann , Aline Mangold

Meta-analysis is a data aggregation method that establishes an overall and objective level of evidence based on the results of several studies. It is necessary to maintain a high level of homogeneity in the aggregation of data collected…

Meta-analysis is commonly used to combine results from multiple clinical trials, but traditional meta-analysis methods do not refer explicitly to a population of individuals to whom the results apply and it is not clear how to use their…

Multiverse analysis, a paradigm for statistical analysis that considers all combinations of reasonable analysis choices in parallel, promises to improve transparency and reproducibility. Although recent tools help analysts specify…

Human-Computer Interaction · Computer Science 2023-06-06 Ken Gu , Eunice Jun , Tim Althoff

Meta-analysis is an important tool for combining results from multiple studies and has been widely used in evidence-based medicine for several decades. This paper reports, for the first time, an interesting and valuable paradox in…

Applications · Statistics 2019-05-15 Jiandong Shi , Aimin Wu , Tiejun Tong

Explanation methods and their evaluation have become a significant issue in explainable artificial intelligence (XAI) due to the recent surge of opaque AI models in decision support systems (DSS). Since the most accurate AI models are…

Artificial Intelligence · Computer Science 2023-08-30 Helena Löfström , Karl Hammar , Ulf Johansson

Random-effects meta-analyses of observational studies can produce biased estimates if the synthesized studies are subject to unmeasured confounding. We propose sensitivity analyses quantifying the extent to which unmeasured confounding of…

Methodology · Statistics 2017-10-10 Maya B. Mathur , Tyler J. VanderWeele

This paper addresses a significant gap in explainable AI: the necessity of interpreting epistemic uncertainty in model explanations. Although current methods mainly focus on explaining predictions, with some including uncertainty, they fail…

Artificial Intelligence · Computer Science 2024-10-10 Helena Löfström , Tuwe Löfström , Johan Hallberg Szabadvary

The overall predictive uncertainty of a trained predictor can be decomposed into separate contributions due to epistemic and aleatoric uncertainty. Under a Bayesian formulation, assuming a well-specified model, the two contributions can be…

Machine Learning · Computer Science 2021-10-22 Sharu Theresa Jose , Sangwoo Park , Osvaldo Simeone

Meta-analysis can be a critical part of the research process, often serving as the primary analysis on which the practitioners, policymakers, and individuals base their decisions. However, current literature synthesis approaches to…

Methodology · Statistics 2023-08-28 Lily H. Zhang , Menelaos Konstantinidis , Marie-Abèle Bind , Donald B. Rubin
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