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Cell layers eliminate unwanted cells through the extrusion process, which underlines healthy versus flawed tissue behaviors. Although several biochemical pathways have been identified, the underlying mechanical basis including the forces…

Soft Condensed Matter · Physics 2023-04-20 Siavash Monfared , Guruswami Ravichandran , Jose E. Andrade , Amin Doostmohammadi

A molecular-dynamics type simulation method, which is suitable for investigating the dewetting dynamics of thin and viscous liquid layers, is discussed. The efficiency of the method is exemplified by studying a two-parameter depinning-like…

Soft Condensed Matter · Physics 2015-06-22 Botond Tyukodi , Yves Brechet , Zoltan Neda

We discuss the sharp interface limit of a diffuse interface model for a two-phase flow of two partly miscible viscous Newtonian fluids of different densities, when a certain parameter \epsilon>0 related to the interface thickness tends to…

Analysis of PDEs · Mathematics 2012-12-24 Helmut Abels , Daniel Lengeler

In this paper, we propose and analyze a diffuse interface model for inductionless magnetohydrodynamic fluids. The model couples a convective Cahn-Hilliard equation for the evolution of the interface, the Navier-Stokes system for fluid flow…

Analysis of PDEs · Mathematics 2023-12-20 Xiaodi Zhang

The diffuse-interface model (DIM) is a tool for studying interfacial dynamics. In particular, it is used for modeling contact lines, i.e., curves where a liquid, gas, and solid are in simultaneous contact. As well as all other models of…

Soft Condensed Matter · Physics 2021-09-17 E. S. Benilov

Research in cell biology is steadily contributing new knowledge about many different aspects of physiological processes like polymerization, both with respect to the involved molecular structures as well as their related function.…

Human-Computer Interaction · Computer Science 2014-07-15 Ivan Kolesar , Julius Parulek , Ivan Viola , Stefan Bruckner , Anne-Kristin Stavrum , Helwig Hauser

A thermodynamically consistent phase-field model is introduced for simulating multicellular deformation, and aggregation under flow conditions. In particular, a Lennard-Jones type potential is proposed under the phase-field framework for…

Numerical Analysis · Mathematics 2022-05-17 Lingyue Shen , Ping Lin , Zhiliang Xu , Shixin Xu

This paper deals with the evolution equation of a curve obtained as the sharp interface limit of a non-linear system of two reaction-diffusion PDEs. This system was introduced as a phase-field model of (crawling) motion of eukaryotic cells…

Analysis of PDEs · Mathematics 2016-03-23 Matthew S. Mizuhara , Leonid Berlyand , Volodymyr Rybalko , Lei Zhang

Reaction-diffusion models with nonlocal constraints naturally arise as limiting cases of coupled bulk-surface models of intracellular signalling. In this paper, a minimal, mass-conserving model of cell-polarization on a curved membrane is…

Pattern Formation and Solitons · Physics 2022-10-04 Pearson W. Miller , Daniel Fortunato , Matteo Novaga , Stanislav Y. Shvartsman , Cyrill B. Muratov

We use a phase-separated driven two-dimensional Ising lattice gas to study fluid interfaces exposed to shear flow parallel to the interface. The interface is stabilized by two parallel walls with opposing surface fields and a driving field…

Statistical Mechanics · Physics 2009-11-13 Thomas H. R. Smith , Oleg Vasilyev , Douglas B. Abraham , Anna Maciołek , Matthias Schmidt

Diffuse-interface theory provides a foundation for the modeling and simulation of microstructure evolution in a very wide range of materials, and for the tracking/capturing of dynamic interfaces between different materials on larger scales.…

Computational Physics · Physics 2018-08-03 Zhijie Xu , Paul Meakin , Alexandre Tartakovsky

We investigate two-phase flow in porous media and derive a two-scale model, which incorporates pore-scale phase distribution and surface tension into the effective behavior at the larger Darcy scale. The free-boundary problem at the pore…

Analysis of PDEs · Mathematics 2023-07-03 Mathis Kelm , Carina Bringedal , Bernd Flemisch

The self-organization of proteins into enriched compartments and the formation of complex patterns are crucial processes for life on the cellular level. Liquid-liquid phase separation is one mechanism for forming such enriched compartments.…

Soft Condensed Matter · Physics 2025-04-07 Antonia Winter , Yuhao Liu , Alexander Ziepke , George Dadunashvili , Erwin Frey

Long linear polymers in a depinned interfaces environment have been studied for a long time, for instance in \cite{Caravenna2009depinning} when the temperature is constant. In this paper, we study an extension of this model by making the…

Probability · Mathematics 2024-10-10 Angot Elric

We consider a model system consisting of two reaction-diffusion equations, where one species diffuses in a volume while the other species diffuses on the surface which surrounds the volume. The two equations are coupled via a nonlinear…

Analysis of PDEs · Mathematics 2017-07-21 Tang Quoc Bao , Klemens Fellner , Evangelos Latos

Dynamic wetting poses a well-known challenge in classical sharp-interface formulation as the no-slip wall condition leads to a contact line singularity that is typically regularized with a Navier boundary condition, often requiring…

Fluid Dynamics · Physics 2025-11-13 Tomas Fullana , Stéphane Zaleski , Gustav Amberg

Motivated by the drying pattern experiment by Yamazaki and Mizuguchi[J. Phys. Soc. Jpn. {\bf 69} (2000) 2387], we propose the dynamics of sweeping interface, in which material distributed over a region is swept by a moving interface. A…

Statistical Mechanics · Physics 2007-06-26 Takuya Iwashita , Yumino Hayase , Hiizu Nakanishi

We study molecular dynamics within populations of diffusively coupled cells under the assumption of fast diffusive exchange. As a technical tool, we propose conditions on boundedness and ultimate boundedness for systems with a singular…

Cell Behavior · Quantitative Biology 2012-12-19 Steffen Waldherr , Frank Allgöwer

A coarse grained description of a two phase fluid is used to study the steady state configuration of the interface separating the coexisting phases, and the motion of the contact line at which the interface intersects a solid boundary. The…

Statistical Mechanics · Physics 2009-10-31 Hsuan-Yi Chen , David Jasnow , Jorge Vinals

In this paper, a thermal-dynamical consistent model for mass transfer across permeable moving interfaces is proposed by using the energy variation method. We consider a restricted diffusion problem where the flux across the interface…

Numerical Analysis · Mathematics 2022-06-15 Yuzhe Qin , Huaxiong Huang , Yi Zhu , Chun Liu , Shixin Xu
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