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Hypergraph data, which capture multi-way interactions among entities, are increasingly prevalent in the big data era. Generating new hyperlinks from an observed, usually high-dimensional hypergraph is an important yet challenging task with…

Methodology · Statistics 2026-05-14 Shihao Wu , Junyi Yang , Gongjun Xu , Ji Zhu

Within cardiovascular disease detection using deep learning applied to ECG signals, the complexities of handling physiological signals have sparked growing interest in leveraging deep generative models for effective data augmentation. In…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Nour Neifar , Achraf Ben-Hamadou , Afef Mdhaffar , Mohamed Jmaiel

Electronic Health Records (EHRs) are a valuable asset to facilitate clinical research and point of care applications; however, many challenges such as data privacy concerns impede its optimal utilization. Deep generative models,…

Machine Learning · Computer Science 2024-01-12 Ghadeer Ghosheh , Jin Li , Tingting Zhu

Generating synthetic Electronic Health Records (EHRs) offers significant potential for data augmentation, privacy-preserving data sharing, and improving machine learning model training. We propose a novel tokenization strategy tailored for…

Machine Learning · Computer Science 2024-11-21 Hojjat Karami , David Atienza , Anisoara Ionescu

The recent availability of electronic health records (EHRs) have provided enormous opportunities to develop artificial intelligence (AI) algorithms. However, patient privacy has become a major concern that limits data sharing across…

Machine Learning · Computer Science 2023-02-01 Jin Li , Benjamin J. Cairns , Jingsong Li , Tingting Zhu

The rapid growth of Electronic Health Records (EHRs), as well as the accompanied opportunities in Data-Driven Healthcare (DDH), has been attracting widespread interests and attentions. Recent progress in the design and applications of deep…

Machine Learning · Computer Science 2017-09-07 Zhengping Che , Yu Cheng , Shuangfei Zhai , Zhaonan Sun , Yan Liu

Recent advances in computer vision have shown promising results in image generation. Diffusion probabilistic models in particular have generated realistic images from textual input, as demonstrated by DALL-E 2, Imagen and Stable Diffusion.…

Accessing longitudinal multimodal Electronic Healthcare Records (EHRs) is challenging due to privacy concerns, which hinders the use of ML for healthcare applications. Synthetic EHRs generation bypasses the need to share sensitive real…

Computation and Language · Computer Science 2022-11-04 Zifeng Wang , Jimeng Sun

Electroencephalography (EEG) is a widely used, non-invasive method for capturing brain activity, and is particularly relevant for applications in Brain-Computer Interfaces (BCI). However, collecting high-quality EEG data remains a major…

Signal Processing · Electrical Eng. & Systems 2025-10-22 Henrique de Lima Alexandre , Clodoaldo Aparecido de Moraes Lima

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Generative models have been found effective for data synthesis due to their ability to capture complex underlying data distributions. The quality of generated data from these models is commonly evaluated by visual inspection for image…

Machine Learning · Computer Science 2022-10-18 Emily Muller , Xu Zheng , Jer Hayes

A variety of methods existing for generating synthetic electronic health records (EHRs), but they are not capable of generating unstructured text, like emergency department (ED) chief complaints, history of present illness or progress…

Computation and Language · Computer Science 2018-12-18 Scott Lee

Synthetic data generation is a promising solution to address privacy issues with the distribution of sensitive health data. Recently, diffusion models have set new standards for generative models for different data modalities. Also very…

Signal Processing · Electrical Eng. & Systems 2023-06-16 Juan Miguel Lopez Alcaraz , Nils Strodthoff

Synthetic Electronic Health Records (EHR) have emerged as a pivotal tool in advancing healthcare applications and machine learning models, particularly for researchers without direct access to healthcare data. Although existing methods,…

The scarcity of accessible, compliant, and ethically sourced data presents a considerable challenge to the adoption of artificial intelligence (AI) in sensitive fields like healthcare, finance, and biomedical research. Furthermore, access…

Machine Learning · Computer Science 2025-04-02 Kumar Kshitij Patel , Weitong Zhang , Lingxiao Wang

We propose RareGraph-Synth, a knowledge-guided, continuous-time diffusion framework that generates realistic yet privacy-preserving synthetic electronic-health-record (EHR) trajectories for ultra-rare diseases. RareGraph-Synth unifies five…

Machine Learning · Computer Science 2025-10-09 Khartik Uppalapati , Shakeel Abdulkareem , Bora Yimenicioglu

Electronic health records (EHR) often contain different rates of representation of certain subpopulations (SP). Factors like patient demographics, clinical condition prevalence, and medical center type contribute to this…

Machine Learning · Computer Science 2024-03-12 Oriel Perets , Nadav Rappoport

Synthetic electronic health records (EHRs) that are both realistic and preserve privacy can serve as an alternative to real EHRs for machine learning (ML) modeling and statistical analysis. However, generating high-fidelity and granular…

Machine Learning · Computer Science 2023-11-13 Brandon Theodorou , Cao Xiao , Jimeng Sun

In this paper, we introduce the first diffusion model designed to generate complete synthetic human genotypes, which, by standard protocols, one can straightforwardly expand into full-length, DNA-level genomes. The synthetic genotypes mimic…

Computational Engineering, Finance, and Science · Computer Science 2025-01-31 Philip Kenneweg , Raghuram Dandinasivara , Xiao Luo , Barbara Hammer , Alexander Schönhuth

Electronic health records (EHRs) offer great promises for advancing precision medicine and, at the same time, present significant analytical challenges. Particularly, it is often the case that patient-level data in EHRs cannot be shared…

Methodology · Statistics 2022-07-04 Changgee Chang , Zhiqi Bu , Qi Long