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As a widely recognized approach to deep generative modeling, Variational Auto-Encoders (VAEs) still face challenges with the quality of generated images, often presenting noticeable blurriness. This issue stems from the unrealistic…

Machine Learning · Computer Science 2023-05-22 Georgios Batzolis , Jan Stanczuk , Carola-Bibiane Schönlieb

Unsupervised learning can leverage large-scale data sources without the need for annotations. In this context, deep learning-based autoencoders have shown great potential in detecting anomalies in medical images. However, especially…

Image and Video Processing · Electrical Eng. & Systems 2020-01-03 David Zimmerer , Simon Kohl , Jens Petersen , Fabian Isensee , Klaus Maier-Hein

Unsupervised learning with functional data is an emerging paradigm of machine learning research with applications to computer vision, climate modeling and physical systems. A natural way of modeling functional data is by learning operators…

Machine Learning · Computer Science 2023-02-22 Jacob H. Seidman , Georgios Kissas , George J. Pappas , Paris Perdikaris

Advancements in digital imaging technologies have sparked increased interest in using multiplexed immunofluorescence (mIF) images to visualise and identify the interactions between specific immunophenotypes with the tumour microenvironment…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Piumi Sandarenu , Julia Chen , Iveta Slapetova , Lois Browne , Peter H. Graham , Alexander Swarbrick , Ewan K. A. Millar , Yang Song , Erik Meijering

Often the analysis of time-dependent chemical and biophysical systems produces high-dimensional time-series data for which it can be difficult to interpret which individual features are most salient. While recent work from our group and…

In this paper, we propose a new method to perform data augmentation in a reliable way in the High Dimensional Low Sample Size (HDLSS) setting using a geometry-based variational autoencoder. Our approach combines a proper latent space…

Machine Learning · Statistics 2023-01-18 Clément Chadebec , Elina Thibeau-Sutre , Ninon Burgos , Stéphanie Allassonnière

The throughput of electron microscopes has increased significantly in recent years, enabling detailed analysis of cell morphology and ultrastructure. Analysis of neural circuits at single-synapse resolution remains the flagship target of…

Computer Vision and Pattern Recognition · Computer Science 2019-08-07 Constantin Pape , Alex Matskevych , Adrian Wolny , Julian Hennies , Giula Mizzon , Marion Louveaux , Jacob Musser , Alexis Maizel , Detlev Arendt , Anna Kreshuk

We develop a framework for incorporating structured graphical models in the \emph{encoders} of variational autoencoders (VAEs) that allows us to induce interpretable representations through approximate variational inference. This allows us…

Wide accessibility of imaging and profile sensors in modern industrial systems created an abundance of high-dimensional sensing variables. This led to a a growing interest in the research of high-dimensional process monitoring. However,…

Machine Learning · Computer Science 2022-08-15 Nurettin Sergin , Hao Yan

The improved diagnostic accuracy of ultrasound breast examinations remains an important goal. In this study, we propose a biophysical feature based machine learning method for breast cancer detection to improve the performance beyond a…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Jihye Baek , Avice M. O'Connell , Kevin J. Parker

Magnetic Resonance Imaging (MRI) is a pivotal clinical diagnostic tool, yet its extended scanning times often compromise patient comfort and image quality, especially in volumetric, temporal and quantitative scans. This review elucidates…

Digitalization leads to data transparency for production systems that we can benefit from with data-driven analysis methods like neural networks. For example, automated anomaly detection enables saving resources and optimizing the…

Machine Learning · Computer Science 2021-06-23 Tom Hammerbacher , Markus Lange-Hegermann , Gorden Platz

Many of the existing machine learning algorithms, both supervised and unsupervised, depend on the quality of the input characteristics to generate a good model. The amount of these variables is also important, since performance tends to…

Machine Learning · Computer Science 2018-01-08 David Charte , Francisco Charte , Salvador García , María J. del Jesus , Francisco Herrera

Time-domain astrophysics relies on heterogeneous and multi-modal data. Specialized models are often constructed to extract information from a single modality, but this approach ignores the wealth of cross-modality information that may be…

Instrumentation and Methods for Astrophysics · Physics 2025-07-23 Yunyi Shen , Alexander T. Gagliano

Layered materials (LMs) are at the centre of an ever increasing research effort due to their potential use in a variety of applications. The presence of imperfections, such as bi- or multilayer areas, holes, grain boundaries, isotropic and…

Rapid progress in aberration corrected electron microscopy necessitates development of robust methods for the identification of phases, ferroic variants, and other pertinent aspects of materials structure from imaging data. While…

The heterogeneous micromechanical properties of biological tissues have profound implications across diverse medical and engineering domains. However, identifying full-field heterogeneous elastic properties of soft materials using…

Numerical Analysis · Mathematics 2025-07-09 Wensi Wu , Mitchell Daneker , Kevin T. Turner , Matthew A. Jolley , Lu Lu

Autoencoders can be challenged by spatially non-uniform sampling of image content. This is common in medical imaging, biology, and physics, where informative patterns occur rarely at specific image coordinates, as background dominates these…

Computer Vision and Pattern Recognition · Computer Science 2026-04-03 Alejandro Castañeda Garcia , Jan van Gemert , Daan Brinks , Nergis Tömen

Variational autoencoders employ an encoding neural network to generate a probabilistic representation of a data set within a low-dimensional space of latent variables followed by a decoding stage that maps the latent variables back to the…

Statistical Mechanics · Physics 2022-04-13 David Yevick

High resolution galaxy spectra contain much information about galactic physics, but the high dimensionality of these spectra makes it difficult to fully utilize the information they contain. We apply variational autoencoders (VAEs), a…

Instrumentation and Methods for Astrophysics · Physics 2020-07-13 Stephen K. N. Portillo , John K. Parejko , Jorge R. Vergara , Andrew J. Connolly