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Longitudinal assessment of brain atrophy, particularly in the hippocampus, is a well-studied biomarker for neurodegenerative diseases, such as Alzheimer's disease (AD). In clinical trials, estimation of brain progressive rates can be…

Neurons and Cognition · Quantitative Biology 2023-04-11 Mengjin Dong , Long Xie , Sandhitsu R. Das , Jiancong Wang , Laura E. M. Wisse , Robin deFlores , David A. Wolk , Paul A. Yushkevich

We present a proof-of-concept, deep learning (DL) based, differentiable biomechanical model of realistic brain deformations. Using prescribed maps of local atrophy and growth as input, the network learns to deform images according to a…

Machine Learning · Computer Science 2020-12-15 Mariana da Silva , Kara Garcia , Carole H. Sudre , Cher Bass , M. Jorge Cardoso , Emma Robinson

Longitudinal analysis has great potential to reveal developmental trajectories and monitor disease progression in medical imaging. This process relies on consistent and robust joint 4D segmentation. Traditional techniques are dependent on…

Machine Learning · Computer Science 2019-06-19 Malav Bateriwala , Pierrick Bourgeat

Ultrasound Localization Microscopy (ULM) can map microvessels at a resolution of a few micrometers (\mu m). Transcranial ULM remains challenging in presence of aberrations caused by the skull, which lead to localization errors. Herein, we…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Paul Xing , Jonathan Porée , Brice Rauby , Antoine Malescot , Éric Martineau , Vincent Perrot , Ravi L. Rungta , Jean Provost

Building accurate Deep Learning (DL) models for brain age prediction is a very relevant topic in neuroimaging, as it could help better understand neurodegenerative disorders and find new biomarkers. To estimate accurate and generalizable…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Carlo Alberto Barbano , Benoit Dufumier , Edouard Duchesnay , Marco Grangetto , Pietro Gori

Approximately 1.2% of the world's population has impaired voice production. As a result, automatic dysphonic voice detection has attracted considerable academic and clinical interest. However, existing methods for automated voice assessment…

Sound · Computer Science 2023-01-27 Jianwei Zhang , Julie Liss , Suren Jayasuriya , Visar Berisha

Deep neural networks trained with standard cross-entropy loss are more prone to memorize noisy labels, which degrades their performance. Negative learning using complementary labels is more robust when noisy labels intervene but with an…

Machine Learning · Computer Science 2022-09-07 Chen-Chen Zong , Zheng-Tao Cao , Hong-Tao Guo , Yun Du , Ming-Kun Xie , Shao-Yuan Li , Sheng-Jun Huang

Blood pressure (BP) is one of the most influential bio-markers for cardiovascular diseases and stroke; therefore, it needs to be regularly monitored to diagnose and prevent any advent of medical complications. Current cuffless approaches to…

Machine Learning · Computer Science 2021-11-30 Rishi Vardhan K , Vedanth S , Poojah G , Abhishek K , Nitish Kumar M , Vineeth Vijayaraghavan

Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Victor Saase , Holger Wenz , Thomas Ganslandt , Christoph Groden , Máté E. Maros

Deep regression is an important problem with numerous applications. These range from computer vision tasks such as age estimation from photographs, to medical tasks such as ejection fraction estimation from echocardiograms for disease…

Computer Vision and Pattern Recognition · Computer Science 2023-02-16 Weihang Dai , Xiaomeng Li , Kwang-Ting Cheng

Objective: Model based deep learning (MBDL) has been challenging to apply to the reconstruction of 3D non-Cartesian MRI acquisitions due to extreme GPU memory demand (>250 GB using traditional backpropagation) primarily because the entire…

Medical Physics · Physics 2023-04-05 Zachary Miller , Ali Pirasteh , Kevin M. Johnson

The use of supervised deep learning techniques to detect pathologies in brain MRI scans can be challenging due to the diversity of brain anatomy and the need for annotated data sets. An alternative approach is to use unsupervised anomaly…

Image and Video Processing · Electrical Eng. & Systems 2023-03-08 Finn Behrendt , Debayan Bhattacharya , Julia Krüger , Roland Opfer , Alexander Schlaefer

Maintaining or improving the performance of Deep Neural Networks (DNNs) through fine-tuning requires labeling newly collected inputs, a process that is often costly and time-consuming. To alleviate this problem, input selection approaches…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Amin Abbasishahkoo , Mahboubeh Dadkhah , Lionel Briand

Large language models (LLMs) have demonstrated remarkable performance across diverse tasks by encoding vast amounts of factual knowledge. However, they are still prone to hallucinations, generating incorrect or misleading information, often…

Computation and Language · Computer Science 2025-11-13 Xiaomin Li , Zhou Yu , Ziji Zhang , Yingying Zhuang , Swair Shah , Narayanan Sadagopan , Anurag Beniwal

Deep generative models are rapidly gaining traction in medical imaging. Nonetheless, most generative architectures struggle to capture the underlying probability distributions of volumetric data, exhibit convergence problems, and offer no…

Machine Learning · Computer Science 2019-07-29 Guilherme Pombo , Robert Gray , Tom Varsavsky , John Ashburner , Parashkev Nachev

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

In this work, we used a semi-supervised learning method to train deep learning model that can segment the brain MRI images. The semi-supervised model uses less labeled data, and the performance is competitive with the supervised model with…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Hedong Zhang , Anand A. Joshi

Super-resolution is widely used in medical imaging to enhance low-quality data, reducing scan time and improving abnormality detection. Conventional super-resolution approaches typically rely on paired datasets of downsampled and original…

Computer Vision and Pattern Recognition · Computer Science 2026-02-18 Xiaoyi Wen , Fei Jiang

Learning from previously collected data via behavioral cloning or offline reinforcement learning (RL) is a powerful recipe for scaling generalist agents by avoiding the need for expensive online learning. Despite strong generalization in…

Important applications of advancements in machine learning, are in the area of healthcare, more so for neurological disorder detection. A crucial step towards understanding the neurological status, is to estimate the brain age using…

Image and Video Processing · Electrical Eng. & Systems 2024-07-10 Vamshi Krishna Kancharla , Neelam Sinha