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We introduce a framework for the calculation of ground and excited state energies of bosonic systems suitable for near-term quantum devices and apply it to molecular vibrational anharmonic Hamiltonians. Our method supports generic reference…

Quantum Physics · Physics 2020-06-24 Pauline J. Ollitrault , Alberto Baiardi , Markus Reiher , Ivano Tavernelli

A combined approach that uses the vibrational self-consistent field (VSCF) and vibrational configuration interaction (VCI) method together with the semiclassical instanton theory was developed to study vibrational tunneling spectra of…

Chemical Physics · Physics 2022-02-07 Mihael Eraković , Marko T. Cvitaš

We aim to automatize the identification of collective variables to simplify and speed up enhanced sampling simulations of conformational dynamics in biomolecules. We focus on anharmonic low-frequency vibrations that exhibit fluctuations on…

Statistical Mechanics · Physics 2025-08-01 Souvik Mondal , Michael A. Sauer , Matthias Heyden

In what has been described as the fourth age of Quantum Chemistry, variational nuclear motion programs are now routinely being used to obtain the vibration-rotation levels and corresponding wavefunctions of small molecules to the sort of…

Chemical Physics · Physics 2016-09-23 Jonathan Tennyson

We present a quantum algorithm for calculating the vibronic spectrum of a molecule, a useful but classically hard problem in chemistry. We show several advantages over previous quantum approaches: vibrational anharmonicity is naturally…

Quantum Physics · Physics 2019-08-02 Nicolas P. D. Sawaya , Joonsuk Huh

Determining the vibrational structure of a molecule is central to fundamental applications in several areas, from atmospheric science to catalysis, fuel combustion modeling, biochemical imaging, and astrochemistry. However, when significant…

Quantum Physics · Physics 2021-12-22 Nicolas P. D. Sawaya , Francesco Paesani , Daniel P. Tabor

Machine learning over-fitting caused by data scarcity greatly limits the application of machine learning for molecules. Due to manufacturing processes difference, big data is not always rendered available through computational chemistry…

Machine Learning · Computer Science 2020-11-20 Ziyang Zhang , Yingtao Luo

This article focuses on the prediction of the vibration frequency response of handheld probes. A novel approach that involves machine learning and readily available data from probes was explored. Vibration probes are efficient and…

Applied Physics · Physics 2024-02-09 Roberto San Millán-Castillo , Eduardo Morgado , Rebeca Goya Esteban

Retrieving or generating two-dimensional molecular structures on the basis of vibrational spectra has been well demonstrated via deep learning models. However, deciphering three-dimensional molecular conformations is still challenging,…

Chemical Physics · Physics 2026-04-28 Xin-Yu Lu , De-Yi Lin , Tong Zhu , Bin Ren , Hao Ma , Guo-Kun Liu

This article presents a new method to compute matrices from numerical simulations based on the ideas of sparse sampling and compressed sensing. The method is useful for problems where the determination of the entries of a matrix constitutes…

Chemical Physics · Physics 2014-10-21 Jacob N. Sanders , Xavier Andrade , Alán Aspuru-Guzik

High-level vibrational calculations have been used to investigate anharmonicity in a wide variety of materials using density-functional-theory (DFT) methods. We have developed a new and efficient approach for describing strongly-anharmonic…

Materials Science · Physics 2017-06-20 Joseph C. A. Prentice , R. J. Needs

Matter-wave interferometry is a highly sensitive tool to measure small perturbations in a quantum system. This property allows the creation of precision sensors for dephasing mechanisms such as mechanical vibrations. They are a challenge…

Bayesian Model Calibration is used to revisit the problem of scaling factor calibration for semi-empirical correction of ab initio harmonic properties (e.g. vibrational frequencies and zero-point energies). A particular attention is devoted…

Chemical Physics · Physics 2016-11-15 Pascal Pernot , Fabien Cailliez

Anharmonic vibrational calculations can already be computationally demanding for relatively small molecules. The main bottlenecks lie in the construction of the potential energy surface and in the size of the excitation space in the…

Chemical Physics · Physics 2016-05-05 Pawel T. Panek , Christoph R. Jacob

Molecular vibrations underpin important phenomena such as spectral properties, energy transfer, and molecular bonding. However, obtaining a detailed understanding of the vibrational structure of even small molecules is computationally…

Quantum Physics · Physics 2020-01-24 Sam McArdle , Alex Mayorov , Xiao Shan , Simon Benjamin , Xiao Yuan

Discovering functional crystalline materials through computational methods remains a formidable challenge in materials science. Here, we introduce VQCrystal, an innovative deep learning framework that leverages discrete latent…

Materials Science · Physics 2024-09-11 ZiJie Qiu , Luozhijie Jin , Zijian Du , Hongyu Chen , Yan Cen , Siqi Sun , Yongfeng Mei , Hao Zhang

The purpose of this article is to present theoretical values for the vibrational and rotational g-factors of several diatomic molecules. The calculations have been carried out at the Multi-Configurational Self-Consistent Field (MCSCF) level…

Chemical Physics · Physics 2025-09-24 Anna Thorn Ekstrøm , Stephan P. A. Sauer

A new physical implementation for quantum computation is proposed. The vibrational modes of molecules are used to encode qubit systems. Global quantum logic gates are realized using shaped femtosecond laser pulses which are calculated…

Quantum Physics · Physics 2009-11-07 Carmen M. Tesch , Regina de Vivie-Riedle

Bayesian Model Calibration is used to revisit the problem of scaling factor calibration for semi-empirical correction of ab initio calculations. A particular attention is devoted to uncertainty evaluation for scaling factors, and to their…

Data Analysis, Statistics and Probability · Physics 2009-01-12 Pascal Pernot

A general theory of electronic excitations in aggregates of molecules coupled to intramolecular vibrations and the harmonic environment is developed for simulation of the third-order nonlinear spectroscopy signals. The model is applied in…

Chemical Physics · Physics 2014-01-17 Vytautas Butkus , Leonas Valkunas , Darius Abramavicius