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Quantum computers are inherently affected by noise. While in the long-term error correction codes will account for noise at the cost of increasing physical qubits, in the near-term the performance of any quantum algorithm should be tested…

As a hybrid quantum-classical algorithm, the variational quantum eigensolver is widely applied in quantum chemistry simulations, especially in computing the electronic structure of complex molecular systems. However, on existing noisy…

Quantum Physics · Physics 2025-01-28 Wanqi Sun , Jungang Xu , Chenghua Duan

The presence of noise is the primary challenge in realizing fault-tolerant quantum computers. In this work, we introduce and experimentally validate a novel strategy to circumvent noise by exploiting the phenomenon of metastability, where a…

Quantum Physics · Physics 2026-05-28 Antonio Sannia , Pratik Sathe , Luis Pedro García-Pintos

Quantum algorithm design usually assumes access to a perfect quantum computer with ideal properties like full connectivity, noise-freedom and arbitrarily long coherence time. In Noisy Intermediate-Scale Quantum (NISQ) devices, however, the…

Quantum Physics · Physics 2020-09-11 Xiangzhen Zhou , Sanjiang Li , Yuan Feng

Shallow, CNOT-efficient quantum circuits are crucial for performing accurate computational chemistry simulations on current noisy quantum hardware. Here, we explore the usefulness of non-iterative energy corrections, based on the method of…

Chemical Physics · Physics 2023-05-03 Ilias Magoulas , Francesco A. Evangelista

The factorized form of the unitary coupled-cluster approximation is one of the most promising methodologies to prepare trial states for strongly correlated systems within the variational quantum eigensolver framework. The factorized form of…

Quantum Physics · Physics 2022-01-05 Luogen Xu , Joseph T. Lee , J. K. Freericks

A significant hurdle in the noisy intermediate-scale quantum (NISQ) era is identifying functional quantum circuits. These circuits must also adhere to the constraints imposed by current quantum hardware limitations. Variational quantum…

Quantum Physics · Physics 2024-10-03 Akash Kundu

Variational quantum algorithms are promising applications of noisy intermediate-scale quantum (NISQ) computers. These algorithms consist of a number of separate prepare-and-measure experiments that estimate terms in a Hamiltonian. The…

Quantum Physics · Physics 2020-06-25 Andrew Zhao , Andrew Tranter , William M. Kirby , Shu Fay Ung , Akimasa Miyake , Peter Love

Compressive sensing is a sensing protocol that facilitates reconstruction of large signals from relatively few measurements by exploiting known structures of signals of interest, typically manifested as signal sparsity. Compressive…

Quantum Physics · Physics 2022-08-10 Kyle Sherbert , Naveed Naimipour , Haleh Safavi , Harry Shaw , Mojtaba Soltanalian

Quantum heuristics have shown promise in solving various optimization problems, including lattice protein folding. Equally relevant is the inverse problem, protein design, where one seeks sequences that fold to a given target structure. The…

Quantum Layout Synthesis (QLS) maps a logical quantum circuit to a physical quantum platform. Optimal QLS minimizes circuit size and depth, which is essential to reduce the noise on current quantum platforms. Optimal QLS is an NP-hard…

Quantum Physics · Physics 2025-07-18 Kostiantyn V. Milkevych , Jaco van de Pol , Irfansha Shaik

Current quantum neural networks suffer from extreme sensitivity to both adversarial perturbations and hardware noise, creating a significant barrier to real-world deployment. Existing robustness techniques typically sacrifice clean accuracy…

Quantum Physics · Physics 2026-01-27 Mohamed Afane , Quanjiang Long , Haoting Shen , Ying Mao , Junaid Farooq , Ying Wang , Juntao Chen

Adaptive variational quantum eigensolvers (ADAPT-VQEs) are promising candidates for simulations of strongly correlated systems on near-term quantum hardware. To further improve the noise resilience of these algorithms, recent efforts have…

The successful implementation of algorithms on quantum processors relies on the accurate control of quantum bits (qubits) to perform logic gate operations. In this era of noisy intermediate-scale quantum (NISQ) computing, systematic…

Quantum computing offers unparalleled computational capabilities but faces significant challenges, including limited qubit counts, diverse hardware topologies, and dynamic noise and error rates, which hinder scalability and reliability.…

Quantum Physics · Physics 2025-09-15 Zefan Du , Pedro Chumpitaz Flores , Wenqi Wei , Juntao Chen , Kaixun Hua , Ying Mao

As quantum processors scale, monolithic architectures face growing challenges due to limited qubit density, heterogeneous error profiles, and restricted connectivity. Modular quantum systems, enabled by chip-to-chip coupler-connected…

Quantum Physics · Physics 2025-05-15 Zefan Du , Shuwen Kan , Samuel Stein , Zhiding Liang , Ang Li , Ying Mao

Variational Quantum Algorithms (VQAs) are a promising approach to leverage Noisy Intermediate-Scale Quantum (NISQ) computers. However, choosing optimal quantum circuits that efficiently solve a given VQA problem is a non-trivial task.…

Quantum Physics · Physics 2025-10-07 Swagat Kumar , Jan-Nico Zaech , Colin Michael Wilmott , Luc Van Gool

While variational quantum algorithms (VQAs) have demonstrated considerable success in unconstrained optimization, their application to constrained combinatorial problems face a trade-off. Penalty-based methods, despite their circuit…

Quantum Physics · Physics 2026-03-09 Hui-Min Li , Yuan-Liang Han , Zhi-Xi Wang , Shao-Ming Fei

Variational quantum algorithms are of special importance in the research on quantum computing applications because of their applicability to current Noisy Intermediate-Scale Quantum (NISQ) devices. The main building blocks of these…

Designing compact and accurate circuits for the variational quantum eigensolver (VQE) is a central challenge in near-term quantum chemistry. Existing adaptive methods such as ADAPT-VQE design circuits by iteratively selecting operators from…

Quantum Physics · Physics 2026-05-28 Jianpeng Chen , Zirui Sheng , Cunxi Gong , Weitang Li
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