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As one of the most prevalent neurodegenerative disorders, Parkinson's disease (PD) has a significant impact on the fine motor skills of patients. The complex interplay of different articulators during speech production and realization of…

Resting-state fMRI has become a valuable tool for classifying brain disorders and constructing brain functional connectivity networks by tracking BOLD signals across brain regions. However, existing mod els largely neglect the…

Machine Learning · Computer Science 2025-11-18 Yue Xun , Jiaxing Xu , Wenbo Gao , Chen Yang , Shujun Wang

Understanding how distributed brain regions coordinate to produce behavior requires models that are both predictive and interpretable. We introduce Behavior-Adaptive Connectivity Estimation (BACE), an end-to-end framework that learns…

Neurons and Cognition · Quantitative Biology 2025-10-27 Mehrnaz Asadi , Sina Javadzadeh , Rahil Soroushmojdehi , S. Alireza Seyyed Mousavi , Terence D. Sanger

The brain may be thought of as a many-body architecture with a spatio-temporal dynamics described by neuronal structures. The oscillatory nature of brain activity allows these structures (nodes) to be described as a set of coupled…

Neurons and Cognition · Quantitative Biology 2021-02-03 J. Mendoza-Ruiz , C. E. Alonso-Malaver , M. Valderrama , O. A. Rosso , J. H. Martínez

The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…

Neurons and Cognition · Quantitative Biology 2017-12-22 Ravi Tejwani , Adam Liska , Hongyuan You , Jenna Reinen , Payel Das

Social movements, neurons in the brain or even industrial suppliers are best described by agents evolving on networks with basic interaction rules. In these real systems, the connectivity between agents corresponds to the a critical state…

Physics and Society · Physics 2007-05-23 Philippe Curty

Listeners adapt language comprehension based on their mental representations of speakers, but how these representations are updated remains unclear. We investigated whether listeners probabilistically adapt comprehension based on the…

Neurons and Cognition · Quantitative Biology 2025-10-28 Hanlin Wu , Xiaohui Rao , Zhenguang G Cai

Spontaneous cortical population activity exhibits a multitude of oscillatory patterns, which often display synchrony during slow-wave sleep or under certain anesthetics and stay asynchronous during quiet wakefulness. The mechanisms behind…

Neurons and Cognition · Quantitative Biology 2018-06-20 Rodrigo F. O. Pena , Michael A. Zaks , Antonio C. Roque

Autism spectrum disorder (ASD) is one of the major developmental disorders affecting children. Recently, it has been hypothesized that ASD is associated with atypical brain connectivities. A substantial body of researches use Pearson's…

Neurons and Cognition · Quantitative Biology 2019-03-06 Biwei Huang , Kun Zhang , Ruben Sanchez-Romero , Joseph Ramsey , Madelyn Glymour , Clark Glymour

Resting-state functional MRI (rs-fMRI) in functional neuroimaging techniques have improved in brain disorders, dysfunction studies via mapping the topology of the brain connections, i.e. connectopic mapping. Since, there are the slight…

Image and Video Processing · Electrical Eng. & Systems 2019-07-18 Jalal Mirakhorli , Hamidreza Amindavar , Mojgan Mirakhorli

Brain structural connectivity, capturing the white matter fiber tracts among brain regions inferred by diffusion MRI (dMRI), provides a unique characterization of brain anatomical organization. One fundamental question to address with…

Neurons and Cognition · Quantitative Biology 2023-04-05 Selena Wang , Yiting Wang , Frederick H. Xu , Li Shen , Yize Zhao

Topological data analysis (TDA) approaches are becoming increasingly popular for studying the dependence patterns in multivariate time series data. In particular, various dependence patterns in brain networks may be linked to specific tasks…

Methodology · Statistics 2023-12-04 Anass B. El-Yaagoubi , Hernando Ombao

Diverse cognitive processes set different demands on locally segregated and globally integrated brain activity. However, it remains unclear how resting brains configure their functional organization to balance the demands on network…

Neurons and Cognition · Quantitative Biology 2022-04-25 Rong Wang , Mianxin Liu , Xinhong Cheng , Ying Wu , Andrea Hildebrandt , Changsong Zhou

Diffusion MRI imaging and tractography algorithms have enabled the mapping of the macro-scale connectome of the entire brain. At the functional level, probably the simplest way to study the dynamics of macro-scale brain activity is to…

Neurons and Cognition · Quantitative Biology 2022-07-19 Qihang Yao , Manoj Chandrasekaran , Constantine Dovrolis

Graph theoretical approaches have been proven to be effective in the characterization of connected systems, as well as in quantifying their dysfunction due to perturbation. In this paper, we show the advantage of a non-Euclidean…

Quantitative Methods · Quantitative Biology 2024-06-10 Alice Longhena , Martin Guillemaud , Mario Chavez

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

Brain networks in fMRI are typically identified using spatial independent component analysis (ICA), yet mathematical constraints such as sparse coding and positivity both provide alternate biologically-plausible frameworks for generating…

Neurons and Cognition · Quantitative Biology 2016-07-05 Jianwen Xie , Pamela K. Douglas , Ying Nian Wu , Arthur L. Brody , Ariana E. Anderson

Brain network analysis based on functional Magnetic Resonance Imaging (fMRI) is pivotal for diagnosing brain disorders. Existing approaches typically rely on predefined functional sub-networks to construct sub-network associations. However,…

Machine Learning · Computer Science 2026-03-11 Jingfeng Tang , Peng Cao , Guangqi Wen , Jinzhu Yang , Xiaoli Liu , Osmar R. Zaiane

Understanding the complex interplay between the brain and a dynamic environment necessitates the continuous generation and updating of expectations for forthcoming events and their corresponding sensory and motor responses. This study…

Adaptation and Self-Organizing Systems · Physics 2023-08-24 Sina Khoonbani , Hasan Ramezanian

A brain wide association study (BWAS) based on the logistic regression was first developed and applied to a large population of epilepsy patients (168) and healthy controls (136). It was found that the most significant links associated with…

Medical Physics · Physics 2012-09-26 Wei Cheng , Xuejuan Zhang , Ge Tian , Jianfeng Feng , Zhengge Wang , Zhiqiang Zhang , GuangMing Lu
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