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Alzheimer's dementia (AD) is of increasing concern as populations achieve longer lifespans. Many of the recent failed AD clinical trials recruiting cognitively intact individuals had a low number of AD events and were thus underpowered.…
Humans can learn concepts or recognize items from just a handful of examples, while machines require many more samples to perform the same task. In this paper, we build a computational model to investigate the possibility of this kind of…
We develop a data-driven co-segmentation algorithm of passively sensed and self-reported active variables collected through smartphones to identify emotionally stressful states in middle-aged and older patients with mood disorders…
Introduction: It is challenging at baseline to predict when and which individuals who meet criteria for mild cognitive impairment (MCI) will ultimately progress to Alzheimer's disease (AD) dementia. Methods: A deep learning method is…
Automated dementia screening enables early detection and intervention, reducing costs to healthcare systems and increasing quality of life for those affected. Depression has shared symptoms with dementia, adding complexity to diagnoses. The…
INTRODUCTION: Advanced machine learning methods might help to identify dementia risk from neuroimaging, but their accuracy to date is unclear. METHODS: We systematically reviewed the literature, 2006 to late 2016, for machine learning…
We classify very-mild to moderate dementia in patients (CDR ranging from 0 to 2) using a support vector machine classifier acting on dimensionally reduced feature set derived from MRI brain scans of the 416 subjects available in the…
The proportion of elderly people is increasing worldwide, particularly those living alone in Japan. As elderly people get older, their risks of physical disabilities and health issues increase. To automatically discover these issues at a…
Deep learning systems are prone to catastrophic forgetting when learning from a sequence of tasks, as old data from previous tasks is unavailable when learning a new task. To address this, some methods propose replaying data from previous…
Recognizing human activities in a sequence is a challenging area of research in ubiquitous computing. Most approaches use a fixed size sliding window over consecutive samples to extract features---either handcrafted or learned…
This Signal Processing Grand Challenge (SPGC) targets a difficult automatic prediction problem of societal and medical relevance, namely, the detection of Alzheimer's Dementia (AD). Participants were invited to employ signal processing and…
Numerous studies attempt to mitigate classification bias caused by class imbalance. However, existing studies have yet to explore the collaborative optimization of imbalanced learning and model training. This constraint hinders further…
Background: Dementia, marked by cognitive decline, is a global health challenge. Alzheimer's disease (AD), the leading type, accounts for ~70% of cases. Electroencephalography (EEG) measures show promise in identifying AD risk, but…
Imbalanced datasets pose significant challenges in areas including neuroscience, cognitive science, and medical diagnostics, where accurately detecting minority classes is essential for robust model performance. This study addresses the…
Alzheimer's disease (AD) poses significant global health challenges due to its increasing prevalence and associated societal costs. Early detection and diagnosis of AD are critical for delaying progression and improving patient outcomes.…
Alzheimer's disease (AD) is a progressive neurological disorder, meaning that the symptoms develop gradually throughout the years. It is also the main cause of dementia, which affects memory, thinking skills, and mental abilities. Nowadays,…
Joint models initially dedicated to a single longitudinal marker and a single time-to-event need to be extended to account for the rich longitudinal data of cohort studies. Multiple causes of clinical progression are indeed usually…
INTRODUCTION: Mild cognitive impairment (MCI) is characterized by a decline in cognitive functions beyond typical age and education-related expectations. Since, MCI has been linked to reduced social interactions and increased aimless…
Current work on speech-based dementia assessment focuses on either feature extraction to predict assessment scales, or on the automation of existing test procedures. Most research uses public data unquestioningly and rarely performs a…
Ensuring the safety and well-being of elderly and vulnerable populations in assisted living environments is a critical concern. Computer vision presents an innovative and powerful approach to predicting health risks through video…