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Deep generative models have been praised for their ability to learn smooth latent representation of images, text, and audio, which can then be used to generate new, plausible data. However, current generative models are unable to work with…

Machine Learning · Computer Science 2019-09-09 Bidisha Samanta , Abir De , Gourhari Jana , Pratim Kumar Chattaraj , Niloy Ganguly , Manuel Gomez-Rodriguez

Euclidean geometry has historically been the typical "workhorse" for machine learning applications due to its power and simplicity. However, it has recently been shown that geometric spaces with constant non-zero curvature improve…

Machine Learning · Computer Science 2020-02-14 Ondrej Skopek , Octavian-Eugen Ganea , Gary Bécigneul

Variational autoencoders (VAEs) have received much attention recently as an end-to-end architecture for text generation with latent variables. In this paper, we investigate several multi-level structures to learn a VAE model to generate…

Computation and Language · Computer Science 2019-06-21 Dinghan Shen , Asli Celikyilmaz , Yizhe Zhang , Liqun Chen , Xin Wang , Jianfeng Gao , Lawrence Carin

The rapid advancement of high-throughput sequencing and other assay technologies has resulted in the generation of large and complex multi-omics datasets, offering unprecedented opportunities for advancing precision medicine strategies.…

Quantitative Methods · Quantitative Biology 2025-01-30 Ana R. Baião , Zhaoxiang Cai , Rebecca C Poulos , Phillip J. Robinson , Roger R Reddel , Qing Zhong , Susana Vinga , Emanuel Gonçalves

Generative Artificial Intelligence (AI) models are a compelling way to introduce K-12 students to AI education using an artistic medium, and hence have drawn attention from K-12 AI educators. Previous Creative AI curricula mainly focus on…

Computers and Society · Computer Science 2022-01-07 Zhuoyue Lyu , Safinah Ali , Cynthia Breazeal

Variational Autoencoders (VAEs) are powerful generative models capable of learning compact latent representations. However, conventional VAEs often generate relatively blurry images due to their assumption of an isotropic Gaussian latent…

Computer Vision and Pattern Recognition · Computer Science 2025-04-21 Andrew Kiruluta

Classical methods for model order selection often fail in scenarios with low SNR or few snapshots. Deep learning-based methods are promising alternatives for such challenging situations as they compensate lack of information in the…

Signal Processing · Electrical Eng. & Systems 2023-12-07 Michael Baur , Franz Weißer , Benedikt Böck , Wolfgang Utschick

Variational Autoencoders (VAEs) provide a theoretically-backed and popular framework for deep generative models. However, learning a VAE from data poses still unanswered theoretical questions and considerable practical challenges. In this…

Machine Learning · Computer Science 2020-06-01 Partha Ghosh , Mehdi S. M. Sajjadi , Antonio Vergari , Michael Black , Bernhard Schölkopf

We propose a variational autoencoder (VAE)-based model for building forward and inverse structure-property linkages, a problem of paramount importance in computational materials science. Our model systematically combines VAE with…

Machine Learning · Computer Science 2024-02-29 Avadhut Sardeshmukh , Sreedhar Reddy , BP Gautham , Pushpak Bhattacharyya

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

Machine Learning · Computer Science 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Variation Autoencoder (VAE) has become a powerful tool in modeling the non-linear generative process of data from a low-dimensional latent space. Recently, several studies have proposed to use VAE for unsupervised clustering by using…

Machine Learning · Computer Science 2021-06-29 Qingyu Zhao , Nicolas Honnorat , Ehsan Adeli , Kilian M. Pohl

Variational Autoencoders and their many variants have displayed impressive ability to perform dimensionality reduction, often achieving state-of-the-art performance. Many current methods however, struggle to learn good representations in…

Machine Learning · Computer Science 2023-06-28 Navindu Leelarathna , Andrei Margeloiu , Mateja Jamnik , Nikola Simidjievski

Variational autoencoders are powerful algorithms for identifying dominant latent structure in a single dataset. In many applications, however, we are interested in modeling latent structure and variation that are enriched in a target…

Machine Learning · Computer Science 2019-02-14 Abubakar Abid , James Zou

A new form of variational autoencoder (VAE) is developed, in which the joint distribution of data and codes is considered in two (symmetric) forms: ($i$) from observed data fed through the encoder to yield codes, and ($ii$) from latent…

Machine Learning · Computer Science 2017-11-21 Yunchen Pu , Weiyao Wang , Ricardo Henao , Liqun Chen , Zhe Gan , Chunyuan Li , Lawrence Carin

The application of deep learning to generative molecule design has shown early promise for accelerating lead series development. However, questions remain concerning how factors like training, dataset, and seed bias impact the technology's…

Biomolecules · Quantitative Biology 2021-09-06 Seung-gu Kang , Joseph A. Morrone , Jeffrey K. Weber , Wendy D. Cornell

The estimation of patient-specific tissue properties in the form of model parameters is important for personalized physiological models. However, these tissue properties are spatially varying across the underlying anatomical model,…

Machine Learning · Statistics 2020-05-19 Jwala Dhamala , Sandesh Ghimire , John L. Sapp , B. Milan Horácek , Linwei Wang

3D geometric contents are becoming increasingly popular. In this paper, we study the problem of analyzing deforming 3D meshes using deep neural networks. Deforming 3D meshes are flexible to represent 3D animation sequences as well as…

Graphics · Computer Science 2018-03-30 Qingyang Tan , Lin Gao , Yu-Kun Lai , Shihong Xia

As one of the most popular generative models, Variational Autoencoder (VAE) approximates the posterior of latent variables based on amortized variational inference. However, when the decoder network is sufficiently expressive, VAE may lead…

Machine Learning · Computer Science 2021-10-26 Dazhong Shen , Chuan Qin , Chao Wang , Hengshu Zhu , Enhong Chen , Hui Xiong

As deep Variational Auto-Encoder (VAE) frameworks become more widely used for modeling biomolecular simulation data, we emphasize the capability of the VAE architecture to concurrently maximize the timescale of the latent space while…

Chemical Physics · Physics 2021-12-08 Hannah K. Wayment-Steele , Vijay S. Pande

Learning a generative model from partial data (data with missingness) is a challenging area of machine learning research. We study a specific implementation of the Auto-Encoding Variational Bayes (AEVB) algorithm, named in this paper as a…

Machine Learning · Computer Science 2021-01-05 Amir Zadeh , Yao-Chong Lim , Paul Pu Liang , Louis-Philippe Morency