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Multi-cancer early detection (MCED) tests offer to screen for multiple types of cancer with a single blood sample. Despite their promising diagnostic performance, evidence regarding their population benefit is not yet available. Expecting…

Applications · Statistics 2023-07-04 Jane M. Lange , Kemal C. Gogebakan , Roman Gulati , Ruth Etzioni

Breast cancer, the second leading cause of cancer-related deaths globally, accounts for a quarter of all cancer cases [1]. To lower this death rate, it is crucial to detect tumors early, as early-stage detection significantly improves…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Samia Saeed , Khuram Naveed

This paper focuses on the task of survival time analysis for lung cancer. Although much progress has been made in this problem in recent years, the performance of existing methods is still far from satisfactory. Traditional and some deep…

Computer Vision and Pattern Recognition · Computer Science 2022-11-08 Yujiao Wu , Yaxiong Wang , Xiaoshui Huang , Fan Yang , Sai Ho Ling , Steven Weidong Su

The advent of large scale, high-throughput genomic screening has introduced a wide range of tests for diagnostic purposes. Prominent among them are tests using miRNA expression levels. Genomics and proteomics now provide expression levels…

Genomics · Quantitative Biology 2016-11-08 Neerja Garikipati

Pacreatic ductal adenocarcinoma (PDAC) remains one of the most lethal forms of cancer, with a five-year survival rate below 10% primarily due to late detection. This research develops and validates a deep learning framework for early PDAC…

Computer Vision and Pattern Recognition · Computer Science 2025-09-12 Dennis Slobodzian , Amir Kordijazi

Early detection of lung nodules is of great importance in lung cancer screening. Existing research recognizes the critical role played by CAD systems in early detection and diagnosis of lung nodules. However, many CAD systems, which are…

Computer Vision and Pattern Recognition · Computer Science 2018-10-18 Naji Khosravan , Ulas Bagci

Survival prediction is a crucial task associated with cancer diagnosis and treatment planning. This paper presents a novel approach to survival prediction by harnessing comprehensive information from CT and PET scans, along with associated…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Aiman Farooq , Deepak Mishra , Santanu Chaudhury

Advances in healthcare research have significantly enhanced our understanding of disease mechanisms, diagnostic precision, and therapeutic options. Yet, lung cancer remains one of the leading causes of cancer-related mortality worldwide due…

Computer Vision and Pattern Recognition · Computer Science 2025-06-06 Sugandha Saxena , S. N. Prasad , Ashwin M Polnaya , Shweta Agarwala

Lung cancer (LC) is a leading cause of cancer-related mortality in the United States. Accurate prediction of LC mortality rates is crucial for guiding targeted interventions and addressing health disparities. Although traditional…

Machine Learning · Computer Science 2025-12-23 Soheil Hashtarkhani , Brianna M. White , Benyamin Hoseini , David L. Schwartz , Arash Shaban-Nejad

Prognostic information at diagnosis has important implications for cancer treatment and monitoring. Although cancer staging, histopathological assessment, molecular features, and clinical variables can provide useful prognostic insights,…

Lung cancer has the highest rate of cancer-caused deaths, and early-stage diagnosis could increase the survival rate. Lung nodules are common indicators of lung cancer, making their detection crucial. Various lung nodule detection models…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Saeed Shakuri , Alireza Rezvanian

Cancer is one of the most dangerous diseases to humans, and yet no permanent cure has been developed for it. Breast cancer is one of the most common cancer types. According to the National Breast Cancer foundation, in 2020 alone, more than…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Ali Bou Nassif , Manar Abu Talib , Qassim Nasir , Yaman Afadar , Omar Elgendy

Background: Stratifying cancer patients according to risk of relapse can personalize their care. In this work, we provide an answer to the following research question: How to utilize machine learning to estimate probability of relapse in…

Accurate segmentation of lung cancer in pathology slides is a critical step in improving patient care. We proposed the ACDC@LungHP (Automatic Cancer Detection and Classification in Whole-slide Lung Histopathology) challenge for evaluating…

In this work, we present a fully automated lung CT cancer diagnosis system, DeepLung. DeepLung contains two parts, nodule detection and classification. Considering the 3D nature of lung CT data, two 3D networks are designed for the nodule…

Computer Vision and Pattern Recognition · Computer Science 2017-09-19 Wentao Zhu , Chaochun Liu , Wei Fan , Xiaohui Xie

Lung cancer is the leading cause of cancer-related deaths in the past several years. A major challenge in lung cancer screening is the detection of lung nodules from computed tomography (CT) scans. State-of-the-art approaches in automated…

Computer Vision and Pattern Recognition · Computer Science 2018-10-05 Aryan Mobiny , Hien Van Nguyen

As advancements in technology and medicine are being made, many countries are still unable to access quality medical care due to cost and lack of qualified medical personnel. This discrepancy in healthcare has caused many preventable…

Image and Video Processing · Electrical Eng. & Systems 2022-10-12 Kyler Larsen

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive cancer, with most cases diagnosed at stage IV and a five-year overall survival rate below 5%. Early detection and prognosis modeling are crucial for improving patient outcomes…

Machine Learning · Computer Science 2025-04-02 David Le , Ramon Correa-Medero , Amara Tariq , Bhavik Patel , Motoyo Yano , Imon Banerjee

Tuberculosis (TB) is still considered a leading cause of death and a substantial threat to global child health. Both TB infection and disease are curable using antibiotics. However, most children who die of TB are never diagnosed or…

Deep learning, as a promising new area of machine learning, has attracted a rapidly increasing attention in the field of medical imaging. Compared to the conventional machine learning methods, deep learning requires no hand-tuned feature…

Quantitative Methods · Quantitative Biology 2016-11-29 He Yang , Hengyong Yu , Ge Wang