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We study the non-equilibrium phase transition in a model for epidemic spreading on scale-free networks. The model consists of two particle species $A$ and $B$, and the coupling between them is taken to be asymmetric; $A$ induces $B$ while…

Statistical Mechanics · Physics 2009-11-11 Yong-Yeol Ahn , Naoki Masuda , Hawoong Jeong , Jae Dong Noh

When the body gets infected by a pathogen the immune system develops pathogen-specific immunity. Induced immunity decays in time and years after recovery the host might become susceptible again. Exposure to the pathogen in the environment…

Dynamical Systems · Mathematics 2014-11-13 Maria Vittoria Barbarossa , Gergely Röst

Understanding how a diversity of plants in agroecosystems affects the adaptation of pathogens in a key issue in agroecology. We analyze PDE systems describing the dynamics of adaptation of two phenotypically structured populations, under…

Analysis of PDEs · Mathematics 2021-03-08 François Hamel , Florian Lavigne , Lionel Roques

In this paper we present a model to estimate the density of aedes mosquitoes in a community affected by dengue. The model is based on the fitting of a continuous function to the incidence of dengue infections, from which the density of…

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

Systems and Control · Electrical Eng. & Systems 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das

Age at infection is often an important factor in epidemic dynamics. In this paper a disease transmission model of SIS type with age dependent infection on a heterogeneous network is discussed. The model allows the infectious rate and the…

Dynamical Systems · Mathematics 2018-06-19 Shanshan Chen , Michael Small , Yizhou Tao , Xinchu Fu

After more than 6 million deaths worldwide, the ongoing vaccination to conquer the COVID-19 disease is now competing with the emergence of increasingly contagious mutations, repeatedly supplanting earlier strains. Following the near-absence…

Populations and Evolution · Quantitative Biology 2022-05-09 Fabian Jan Schwarzendahl , Jens Grauer , Benno Liebchen , Hartmut Löwen

The introduction of Wolbachia-carrying mosquitoes into the population has recently been proposed as an alternative strategy against dengue. Although laboratory experiments have shown that the Wolbachia bacterium can reduce the levels of…

Populations and Evolution · Quantitative Biology 2017-11-13 Meksianis Z. Ndii

Voluntary vaccination is effective to prevent infectious diseases from spreading. Both vaccination behavior and cognition of the vaccination risk play important roles in individual vaccination decision making. However, it is not clear how…

Dynamical Systems · Mathematics 2022-09-21 Yuan Liu , Bin Wu

In the face of serious infectious diseases, governments endeavour to implement containment measures such as public vaccination at a macroscopic level. Meanwhile, individuals tend to protect themselves by avoiding contacts with infections at…

Physics and Society · Physics 2016-10-20 Xiao-Long Peng , Xin-Jian Xu , Michael Small , Xinchu Fu , Zhen Jin

Broadly neutralizing antibodies are promising candidates for treatment and prevention of HIV-1 infections. Such antibodies can temporarily suppress viral load in infected individuals; however, the virus often rebounds by escape mutants that…

Populations and Evolution · Quantitative Biology 2022-10-12 Matthijs Meijers , Kanika Vanshylla , Henning Gruell , Florian Klein , Michael Laessig

Most vaccines require multiple doses, the first to induce recognition and antibody production and subsequent doses to boost the primary response and achieve optimal protection. We show that properly prioritizing the administration of first…

In this paper, we extend the classical SIRS (Susceptible-Infectious-Recovered-Susceptible) model from mathematical epidemiology by incorporating a vaccinated compartment, V, accounting for an imperfect vaccine with waning efficacy over…

Populations and Evolution · Quantitative Biology 2025-01-30 Joseph Páez Chávez , Aytül Gökçe , Thomas Götz , Burcu Gürbüz

The rapid development of vaccines to combat the spread of COVID-19 disease caused by the SARS-CoV-2 virus is a great scientific achievement. Before the development of the COVID-19 vaccines, most studies capitalized on the available data…

During the last decades, the global prevalence of dengue progressed dramatically. It is a disease which is now endemic in more than one hundred countries of Africa, America, Asia and the Western Pacific. This study addresses a mathematical…

Public health services are constantly searching for new ways to reduce the spread of infectious diseases, such as public vaccination of asymptomatic individuals, quarantine (isolation) and treatment of symptomatic individuals. Epidemic…

Populations and Evolution · Quantitative Biology 2018-06-11 Shanshan Chen , Michael Small , Xinchu Fu

We analyse the global dynamics of a Susceptible--Vaccinated--Exposed--Infected--Recovered (SVEIR) epidemic model with demographic turnover, imperfect vaccination, and two transmission routes: direct host-to-host contagion and indirect…

Dynamical Systems · Mathematics 2026-03-31 Emanuela Penitente , Urszula Foryś , Burcu Gürbüz

Although previous infection and vaccination provide protection against SARS-CoV-2 infection, both reinfection and breakthrough infection are possible events whose occurrence would increase with time after first exposure to the antigen and…

Populations and Evolution · Quantitative Biology 2022-06-07 Ariel Félix Gualtieri , Carolina de la Cal , Augusto Francisco Toma , Pedro Hecht

We propose a mathematical model to analyze the effects of anti-infection behavior on the equilibrium states of an infectious disease. The anti-infection behavior is incorporated into a classical epidemiological SIR model, by considering the…

Populations and Evolution · Quantitative Biology 2020-09-11 Andrés David Báez-Sánchez , Nara Bobko

In this paper, we propose a delayed cytokine-enhanced viral infection model incorporating saturation incidence and immune response. We compute the basic reproduction numbers and introduce a convex cone to discuss the impact of non-negative…

Dynamical Systems · Mathematics 2024-09-17 Xiaodong Cao , Songbo Hou , Xiaoqing Kong
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