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The covariance matrix is a foundation in numerous statistical and machine-learning applications such as Principle Component Analysis, Correlation Heatmap, etc. However, missing values within datasets present a formidable obstacle to…

Machine Learning · Statistics 2025-01-22 Tuan L. Vo , Quan Huu Do , Uyen Dang , Thu Nguyen , Pål Halvorsen , Michael A. Riegler , Binh T. Nguyen

High-dimensional vector autoregression with measurement error is frequently encountered in a large variety of scientific and business applications. In this article, we study statistical inference of the transition matrix under this model.…

Methodology · Statistics 2020-09-18 Xiang Lyu , Jian Kang , Lexin Li

We consider the problem of estimating covariance and precision matrices, and their associated discriminant coefficients, from normal data when the rank of the covariance matrix is strictly smaller than its dimension and the available sample…

Statistics Theory · Mathematics 2015-09-09 Didier Chételat , Martin T. Wells

The sample covariance matrix becomes non-invertible in high-dimensional settings, making classical multivariate statistical methods inapplicable. Various regularization techniques address this issue by imposing a structured target matrix to…

Methodology · Statistics 2025-03-13 Atiq Ur Rehman , Muhammad Farooq

Existing high-dimensional statistical methods are largely established for analyzing individual-level data. In this work, we study estimation and inference for high-dimensional linear models where we only observe "proxy data", which include…

Methodology · Statistics 2022-01-12 Sai Li , T. Tony Cai , Hongzhe Li

We consider inference problems for high-dimensional (HD) functional data with a dense number (T) of repeated measurements taken for a large number of p variables from a small number of n experimental units. The spatial and temporal…

Methodology · Statistics 2020-05-06 Shawn Santo , Ping-Shou Zhong

In this paper, we investigate community detection in networks in the presence of node covariates. In many instances, covariates and networks individually only give a partial view of the cluster structure. One needs to jointly infer the full…

Methodology · Statistics 2018-04-26 Bowei Yan , Purnamrita Sarkar

We consider the joint inference of regression coefficients and the inverse covariance matrix for covariates in high-dimensional probit regression, where the predictors are both relevant to the binary response and functionally related to one…

Methodology · Statistics 2022-03-15 Xuan Cao , Kyoungjae Lee

With the increasing availability of various sensor technologies, we now have access to large amounts of multi-block (also called multi-set, multi-relational, or multi-view) data that need to be jointly analyzed to explore their latent…

Computational Engineering, Finance, and Science · Computer Science 2015-09-01 Guoxu Zhou , Qibin Zhao , Yu Zhang , Tülay Adalı , Shengli Xie , Andrzej Cichocki

While a set of covariance matrices corresponding to different populations are unlikely to be exactly equal they can still exhibit a high degree of similarity. For example, some pairs of variables may be positively correlated across most…

Methodology · Statistics 2008-04-02 Peter Hoff

The inverse covariance matrix provides considerable insight for understanding statistical models in the multivariate setting. In particular, when the distribution over variables is assumed to be multivariate normal, the sparsity pattern in…

Machine Learning · Statistics 2017-10-20 Addison Hu , Sahand Negahban

Graphical models are widely used to make inferences concerning interplay in multivariate systems. In many applications, data are collected from multiple related but nonidentical units whose underlying networks may differ but are likely to…

Methodology · Statistics 2014-12-04 Chris J. Oates , Jim Korkola , Joe W. Gray , Sach Mukherjee

We study the problem of treatment effect estimation in randomized experiments with high-dimensional covariate information, and show that essentially any risk-consistent regression adjustment can be used to obtain efficient estimates of the…

Methodology · Statistics 2022-06-08 Stefan Wager , Wenfei Du , Jonathan Taylor , Robert Tibshirani

Analysis of structural and functional connectivity (FC) of human brains is of pivotal importance for diagnosis of cognitive ability. The Human Connectome Project (HCP) provides an excellent source of neural data across different regions of…

Applications · Statistics 2020-07-10 Satwik Acharyya , Zhengwu Zhang , Anirban Bhattacharya , Debdeep Pati

Advances in simultaneous recordings of large numbers of neurons have driven significant interest in the structure of neural population activity such as dimension. A key question is how these dynamic features arise mechanistically and their…

Neurons and Cognition · Quantitative Biology 2025-08-08 Xuanyu Shen , Yu Hu

The application of standard sufficient dimension reduction methods for reducing the dimension space of predictors without losing regression information requires inverting the covariance matrix of the predictors. This has posed a number of…

Methodology · Statistics 2019-10-01 Kabir Opeyemi Olorede , Waheed Babatunde Yahya

Having a large number of covariates can have a negative impact on the quality of causal effect estimation since confounding adjustment becomes unreliable when the number of covariates is large relative to the samples available. Propensity…

Methodology · Statistics 2020-09-15 Debo Cheng , Jiuyong Li , Lin Liu , Jixue Liu

Continuous biomarkers are common for disease screening and diagnosis. To reach a dichotomous clinical decision, a threshold would be imposed to distinguish subjects with disease from non-diseased individuals. Among various performance…

Methodology · Statistics 2021-04-21 Ziyi Li , Yijuan Huang , Dattatraya Patil , Martin G. Sanda

This paper provides a framework for estimating the mean and variance of a high-dimensional normal density. The main setting considered is a fixed number of vector following a high-dimensional normal distribution with unknown mean and…

Methodology · Statistics 2019-05-07 Shyamalendu Sinha , Jeffrey D. Hart

Covariate adjustment is widely recommended to improve statistical efficiency in randomized clinical trials (RCTs), yet empirical evidence comparing available strategies remains limited. This lack of real-world evaluation leaves unresolved…

Applications · Statistics 2026-02-03 Yulin Shao , Liangbo Lyu , Menggang Yu , Bingkai Wang