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Quantum computers are a revolutionary class of computational platforms with applications in combinatorial and global optimization, machine learning, and other domains involving computationally hard problems. While these machines typically…

Quantum Physics · Physics 2026-04-21 Aditya Sodhani , Keshab K. Parhi

Efficient quantum circuit optimization schemes are central to quantum simulation of strongly interacting quantum many body systems. Here, we present an optimization algorithm which combines machine learning techniques and tensor network…

Quantum Physics · Physics 2024-08-23 David Rogerson , Ananda Roy

Quantum computing is an emerging technology in which quantum mechanical properties are suitably utilized to perform certain compute-intensive operations faster than classical computers. Quantum algorithms are designed as a combination of…

Emerging Technologies · Computer Science 2023-06-06 Aravind Joshi , Akshara Kairali , Renju Raju , Adithya Athreya , Reena Monica P , Sanjay Vishwakarma , Srinjoy Ganguly

Existing quantum compilers optimize quantum circuits by applying circuit transformations designed by experts. This approach requires significant manual effort to design and implement circuit transformations for different quantum devices,…

Programming Languages · Computer Science 2022-05-03 Mingkuan Xu , Zikun Li , Oded Padon , Sina Lin , Jessica Pointing , Auguste Hirth , Henry Ma , Jens Palsberg , Alex Aiken , Umut A. Acar , Zhihao Jia

Generative modeling is a flavor of machine learning with applications ranging from computer vision to chemical design. It is expected to be one of the techniques most suited to take advantage of the additional resources provided by…

We provide a simple framework for the synthesis of quantum circuits based on a numerical optimization algorithm. This algorithm is used in the context of the trapped-ions technology. We derive theoretical lower bounds for the number of…

Emerging Technologies · Computer Science 2020-04-17 Timothée Goubault de Brugière , Marc Baboulin , Benoît Valiron , Cyril Allouche

In recent years, parameterized quantum circuits have become a major tool to design quantum algorithms for optimization problems. The challenge in fully taking advantage of a given family of parameterized circuits lies in finding a good set…

Quantum Physics · Physics 2022-09-05 Eunou Lee

The functionality of catalysts, enzymes, and supramolecular assemblies emerges not from individual molecules alone, but from the subtle interplay between multiple components arranged in complex systems. Designing such systems is a grand…

Computational Physics · Physics 2026-04-15 Rhyan Barrett , Robin Curth , Julia Westermayr

Gradient-based optimization is a key ingredient of variational quantum algorithms, with applications ranging from quantum machine learning to quantum chemistry and simulation. The parameter-shift rule provides a hardware-friendly method for…

Quantum Physics · Physics 2025-10-08 Leonardo Banchi , Dominic Branford , Chetan Waghela

Quantum computing is a promising paradigm that may overcome the current computational power bottlenecks. The increasing maturity of quantum processors provides more possibilities for the development and implementation of quantum algorithms.…

Quantum Physics · Physics 2025-10-15 Ge Yan , Wenjie Wu , Yuheng Chen , Kaisen Pan , Xudong Lu , Zixiang Zhou , Yuhan Wang , Ruocheng Wang , Junchi Yan

The development of tailored materials for specific applications is an active field of research in chemistry, material science and drug discovery. The number of possible molecules that can be obtained from a set of atomic species grow…

As we continue to find applications where the currently available noisy devices exhibit an advantage over their classical counterparts, the efficient use of quantum resources is highly desirable. The notion of quantum autoencoders was…

Quantum Physics · Physics 2022-07-08 Abhinav Anand , Jakob S. Kottmann , Alán Aspuru-Guzik

Using the properties of quantum superposition, we propose a quantum classification algorithm to efficiently perform multi-class classification tasks, where the training data are loaded into parameterized operators which are applied to the…

Quantum Physics · Physics 2022-03-09 Anqi Zhang , Xiaoyun He , Shengmei Zhao

This article explores search strategies for the design of parameterized quantum circuits. We propose several optimization approaches including random search plus survival of the fittest, reinforcement learning both with classical and hybrid…

Quantum Physics · Physics 2021-01-05 Mohammad Pirhooshyaran , Tamas Terlaky

We present a computer-aided design flow for quantum circuits, complete with automatic layout and control logic extraction. To motivate automated layout for quantum circuits, we investigate grid-based layouts and show a performance variance…

Quantum Physics · Physics 2009-09-29 Mark Whitney , Nemanja Isailovic , Yatish Patel , John Kubiatowicz

Quantum circuits are time dependent diagrams describing the process of quantum computation. Usually, a quantum algorithm must be mapped into a quantum circuit. Optimal synthesis of quantum circuits is intractable and heuristic methods must…

Quantum Physics · Physics 2008-02-27 D. Maslov , G. W. Dueck , D. M. Miller , C. Negrevergne

The fragile nature of quantum information limits our ability to construct large quantities of quantum bits suitable for quantum computing. An important goal, therefore, is to minimize the amount of resources required to implement quantum…

Quantum Physics · Physics 2013-04-11 Adam Paetznick , Austin G. Fowler

Recent advancements in quantum computing have shown promising computational advantages in many problem areas. As one of those areas with increasing attention, hybrid quantum-classical machine learning systems have demonstrated the…

Neural and Evolutionary Computing · Computer Science 2023-01-18 Li Ding , Lee Spector

Quantum architecture search (QAS) is desired to construct a powerful and general QAS platform which can significantly accelerate quantum advantages in error-prone and depth limited quantum circuits in today Noisy Intermediate-Scale Quantum…

Quantum Physics · Physics 2022-12-02 Anqi Zhang , Shengmei Zhao

Compiling quantum circuits to account for hardware restrictions is an essential part of the quantum computing stack. Circuit compilation allows us to adapt algorithm descriptions into a sequence of operations supported by real quantum…

Quantum Physics · Physics 2025-10-14 Alejandro Villoria , Henning Basold , Alfons Laarman