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In clinical trials the comparison of two different populations is a frequently addressed problem. Non-linear (parametric) regression models are commonly used to describe the relationship between covariates as the dose and a response…

Methodology · Statistics 2019-02-12 Kathrin Möllenhoff , Frank Bretz , Holger Dette

This paper proposes a new test for the comparison of conditional quantile curves when the outcome of interest, typically a duration, is subject to right censoring. The test can be applied both in the case of two independent samples and for…

Methodology · Statistics 2023-02-08 Lorenzo Tedesco , Ingrid Van Keilegom

This article studies the problem whether two convex (concave) regression functions modelling the relation between a response and covariate in two samples differ by a shift in the horizontal and/or vertical axis. We consider a nonparametric…

Statistics Theory · Mathematics 2019-08-14 Holger Dette , Subhra Sankar Dhar , Weichi Wu

The problem of assessing a parametric regression model in the presence of spatial correlation is addressed in this work. For that purpose, a goodness-of-fit test based on a $L_2$-distance comparing a parametric and a nonparametric…

Measuring the similarity of curves is a fundamental problem arising in many application fields. There has been considerable interest in several such measures, both in Euclidean space and in more general setting such as curves on Riemannian…

Computational Geometry · Computer Science 2013-04-01 Erin Wolf Chambers , Yusu Wang

This paper investigates the problem whether the difference between two parametric models $m_1,m_2$ describing the relation between a response variable and several covariates in two different groups is practically irrelevant, such that…

Methodology · Statistics 2016-06-09 Holger Dette , Kathrin Möllenhoff , Stanislav Volgushev , Frank Bretz

In modern experimental science, there is a common problem of estimating the coefficients of a linear regression in a context where the variables of interest cannot be observed simultaneously. When there is a categorical variable that is…

Methodology · Statistics 2025-03-10 Polina Arsenteva , Mohamed Amine Benadjaoud , Hervé Cardot

In this paper we propose a new test for the hypothesis of a constant coefficient of variation in the common nonparametric regression model. The test is based on an estimate of the $L^2$-distance between the square of the regression function…

Statistics Theory · Mathematics 2008-09-30 H. Dette , G. Wieczorek

Are two sets of observations drawn from the same distribution? This problem is a two-sample test. Kernel methods lead to many appealing properties. Indeed state-of-the-art approaches use the $L^2$ distance between kernel-based distribution…

Machine Learning · Statistics 2019-10-02 M. Scetbon , G. Varoquaux

In this paper we propose a new test of heteroscedasticity for parametric regression models and partial linear regression models in high dimensional settings. When the dimension of covariates is large, existing tests of heteroscedasticity…

Methodology · Statistics 2018-08-09 Falong Tan , Xuejun Jiang , Xu Guo , Lixing Zhu

In competing risks models, cumulative incidence functions are commonly compared to infer differences between groups. Many existing inference methods, however, struggle when these functions cross during the time frame of interest. To address…

Methodology · Statistics 2026-01-26 Simon Mack , Marc Ditzhaus , Merle Munko , Markus Pauly

The analysis of continuously spatially varying processes usually considers two sources of variation, namely, the large-scale variation collected by the trend of the process, and the small-scale variation. Parametric trend models on latitude…

A common problem in numerous research areas, particularly in clinical trials, is to test whether the effect of an explanatory variable on an outcome variable is equivalent across different groups. In practice, these tests are frequently…

Methodology · Statistics 2024-05-03 Niklas Hagemann , Kathrin Möllenhoff

This paper addresses the problem of deciding whether the dose response relationships between subgroups and the full population in a multi-regional trial are similar to each other. Similarity is measured in terms of the maximal deviation…

Statistics Theory · Mathematics 2024-04-30 Holger Dette , Lukas Koletzko , Frank Bretz

We analytically study proximity and distance properties of various kernels and similarity measures on graphs. This helps to understand the mathematical nature of such measures and can potentially be useful for recommending the adoption of…

Combinatorics · Mathematics 2018-08-17 Konstantin Avrachenkov , Pavel Chebotarev , Dmytro Rubanov

To address the difficult problem of multi-step ahead prediction of non-parametric autoregressions, we consider a forward bootstrap approach. Employing a local constant estimator, we can analyze a general type of non-parametric time series…

Methodology · Statistics 2023-11-02 Dimitris N. Politis , Kejin Wu

We consider the problem of efficient statistical inference for comparing two regression curves estimated from two samples of dependent measurements. Based on a representation of the best pair of linear unbiased estimators in continuous time…

Methodology · Statistics 2016-01-29 Holger Dette , Kirsten Schorning , Maria Konstantinou

In this paper we study the consistency of different bootstrap procedures for constructing confidence intervals (CIs) for the unique jump discontinuity (change-point) in an otherwise smooth regression function in a stochastic design setting.…

Statistics Theory · Mathematics 2011-01-06 Emilio Seijo , Bodhisattva Sen

In this paper we introduce a kernel-based measure for detecting differences between two conditional distributions. Using the `kernel trick' and nearest-neighbor graphs, we propose a consistent estimate of this measure which can be computed…

Methodology · Statistics 2024-08-30 Anirban Chatterjee , Ziang Niu , Bhaswar B. Bhattacharya

The identification of similar patient pathways is a crucial task in healthcare analytics. A flexible tool to address this issue are parametric competing risks models, where transition intensities may be specified by a variety of parametric…

Methodology · Statistics 2024-01-10 Kathrin Möllenhoff , Nadine Binder , Holger Dette
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