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High throughput screening of small molecules and natural products is costly, requiring significant amounts of time, reagents, and operating space. Although microarrays have proven effective in the miniaturization of screening for certain…
Investigations of free-standing liquid films enjoy an increasing popularity due to their relevance for many fundamental and applied scientific problems. They constitute soap bubbles and foams, serve as membranes for gas transport or as…
Application of Microelectronic to bioanalysis is an emerging field which holds great promise. From the standpoint of electronic and system design, biochips imply a radical change of perspective, since new, completely different constraints…
Analysis of nanoscale liquids, including wetting and flow phenomena, is a scientific challenge with far reaching implications for industrial technologies. We report the conception, development, and application of an integrated platform for…
This chapter presents an overview of microfluidic devices reported in the literature, used to develop methodologies for nucleation of biomolecules, with crystal size control, and for collecting thermodynamic and kinetic data. Part I is…
This work describes a new microfluidic device developed for rapid screening of solubility diagrams. In several parallel channels, hundreds of nanoliter-volume droplets of a given solution are first stored with a gradual variation in the…
Nature is remarkably adept at using interfaces to build structures, encapsulate reagents, and regulate biological processes. Inspired by Nature, we describe flexible polymer-based ribbons, termed "mesoscale polymers" (MSPs), to modulate…
Droplet microlasers, as promising tools for biophotonics and biomedical sciences, have witnessed rapid advances due to their flexible reconfigurability, high sensitivity to stimuli, and label-free biosensing ability. However, designing…
Contact lenses have traditionally been used for vision correction applications. Recent advances in microelectronics and nanofabrication on flexible substrates have now enabled sensors, circuits and other essential components to be…
This comprehensive review discusses the development of scanning electron microscopy and the application of this technology in different fields such as biology, nanobiotechnology and biomedical science. Besides being a tool for high…
We present an extension of the multiparticle collision dynamics method for flows with complex interfaces, including supramolecular near-contact interactions mimicking the effect of surfactants. The new method is demonstrated for the case of…
Model biomembrane systems play a crucial role in advancing biomedical research by providing simplified yet effective platforms for exploring complex biological mechanisms. These systems span a wide range of scales, from…
The development of microfluidic devices is still hindered by the lack of robust fundamental building blocks that constitute any fluidic system. An attractive approach is optical actuation because light field interaction is contactless and…
Microscopic active droplets are able to swim autonomously in viscous flows: this puzzling feature stems from solute exchanges with the surrounding fluid via surface reactions or their spontaneous solubilisation, and the interfacial flows…
In this work, all-silicon, integrated optofluidic platforms, fabricated by electrochemical micromachining technology, making use of vertical, one-dimensional high-aspect- ratio photonic crystals for flow-through (bio)sensing applications…
In microfluidic systems, droplets undergo intricate deformations as they traverse flow-focusing junctions, posing a challenging task for accurate measurement, especially during short transit times. This study investigates the physical…
The dynamics of droplets on substrates has a strong impact on microfluidic systems ranging from commercially available lab-on-chip systems to state of the art developments in open microfluidics. Coalescence of micro and nano droplets on a…
Droplet-droplet interactions is ubiquitous in various applications ranging from medical diagnostics to enhancing and optimizing liquid jet propulsion. We employ an experimental technique where the laser pulse interacts with a micron-sized…
Applications such as digital microfluidics and bio-diagnostics rely on droplet locomotion. A prominent example of such motion is durotaxis, a phenomenon that requires a stiffness gradient along a surface for the transport of liquids, cells,…
The design of complex materials and the formation of specific patterns often arise from the properties of the individual building blocks. In this respect, colloidal systems offer a unique opportunity because nowadays they can be synthesized…