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This paper focuses on three critical problems on protein classification. Firstly, Carbohydrate-active enzyme (CAZyme) classification can help people to understand the properties of enzymes. However, one CAZyme may belong to several classes.…

Biomolecules · Quantitative Biology 2023-02-23 Zhuangwei Shi , Bo Li

Neural operations as convolutions, self-attention, and vector aggregation are the go-to choices for recognizing short-range actions. However, they have three limitations in modeling long-range activities. This paper presents PIC,…

Computer Vision and Pattern Recognition · Computer Science 2020-03-19 Noureldien Hussein , Efstratios Gavves , Arnold W. M. Smeulders

Deep self-expressiveness-based subspace clustering methods have demonstrated effectiveness. However, existing works only consider the attribute information to conduct the self-expressiveness, which may limit the clustering performance. In…

Computer Vision and Pattern Recognition · Computer Science 2022-06-22 Zhihao Peng , Hui Liu , Yuheng Jia , Junhui Hou

The structure of proteins is the basis for studying protein function and drug design. The emergence of AlphaFold 2 has greatly promoted the prediction of protein 3D structures, and it is of great significance to give an overall and accurate…

Biomolecules · Quantitative Biology 2024-07-02 Wenda Wang , Jiaqi Zhai , He Huang , Xinqi Gong

Neural network test cases are meant to exercise different reasoning paths in an architecture and used to validate the prediction outcomes. In this paper, we introduce "computational profiles" as vectors of neuron activation levels. We…

Machine Learning · Computer Science 2021-07-30 Ettore Merlo , Mira Marhaba , Foutse Khomh , Houssem Ben Braiek , Giuliano Antoniol

Feature interaction has been recognized as an important problem in machine learning, which is also very essential for click-through rate (CTR) prediction tasks. In recent years, Deep Neural Networks (DNNs) can automatically learn implicit…

The problem of human activity recognition from mobile sensor data applies to multiple domains, such as health monitoring, personal fitness, daily life logging, and senior care. A critical challenge for training human activity recognition…

Computer Vision and Pattern Recognition · Computer Science 2022-05-10 Abduallah Mohamed , Fernando Lejarza , Stephanie Cahail , Christian Claudel , Edison Thomaz

Deep learning models for drug--target interaction (DTI) prediction often achieve strong benchmark performance without necessarily relying on mechanistically meaningful molecular features, a limitation that standard accuracy-based evaluation…

Machine Learning · Computer Science 2026-05-06 Barbara Tarantino , Sun Kim , Yijingxiu Lu , Paolo Giudici

Sensor-based human activity recognition (HAR) requires to predict the action of a person based on sensor-generated time series data. HAR has attracted major interest in the past few years, thanks to the large number of applications enabled…

Machine Learning · Computer Science 2021-03-30 Davide Buffelli , Fabio Vandin

Graphical structure learning is an effective way to assess and visualize cross-biomarker dependencies in biomedical settings. Standard approaches to estimating graphs rely on conditional independence tests that may not be sensitive to…

Methodology · Statistics 2024-11-28 Zain Khan , Daniel Malinsky , Martin Picard , Alan A. Cohen , Columbia SOH Group , Ying Wei

Properties of molecules are indicative of their functions and thus are useful in many applications. With the advances of deep learning methods, computational approaches for predicting molecular properties are gaining increasing momentum.…

Quantitative Methods · Quantitative Biology 2021-07-07 Zhengyang Wang , Meng Liu , Youzhi Luo , Zhao Xu , Yaochen Xie , Limei Wang , Lei Cai , Qi Qi , Zhuoning Yuan , Tianbao Yang , Shuiwang Ji

Identification of different neuronal cell types is critical for understanding their contribution to brain functions. Yet, automated and reliable classification of neurons remains a challenge, primarily because of their biological…

Neural and Evolutionary Computing · Computer Science 2020-09-29 Eirini Troullinou , Grigorios Tsagkatakis , Spyridon Chavlis , Gergely Turi , Wen-Ke Li , Attila Losonczy , Panagiotis Tsakalides , Panayiota Poirazi

The composite current source (CCS) model has been adopted as an advanced timing model that represents the current behavior of cells for improved accuracy and better capability than traditional non-linear delay models (NLDM) to model complex…

Machine Learning · Computer Science 2025-05-26 Tao Bai , Junzhuo Zhou , Zeyuan Deng , Ting-Jung Lin , Wei Xing , Peng Cao , Lei He

We present data driven deep learning models for forecasting and monitoring amine emissions and key performance parameters in amine-based post-combustion carbon capture systems. Using operational data from the CESAR1 solvent campaign at…

Machine Learning · Computer Science 2025-09-08 Lokendra Poudel , David Tincher , Duy-Nhat Phan , Rahul Bhowmik

Facial Action Units (AUs) represent a set of facial muscular activities and various combinations of AUs can represent a wide range of emotions. AU recognition is often used in many applications, including marketing, healthcare, education,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-09 Junya Saito , Xiaoyu Mi , Akiyoshi Uchida , Sachihiro Youoku , Takahisa Yamamoto , Kentaro Murase , Osafumi Nakayama

The action anticipation task refers to predicting what action will happen based on observed videos, which requires the model to have a strong ability to summarize the present and then reason about the future. Experience and common sense…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Xin Liu , Chao Hao , Zitong Yu , Huanjing Yue , Jingyu Yang

Increasing demands for understanding the internal behavior of convolutional neural networks (CNNs) have led to remarkable improvements in explanation methods. Particularly, several class activation mapping (CAM) based methods, which…

Computer Vision and Pattern Recognition · Computer Science 2021-09-28 Hyungsik Jung , Youngrock Oh

Protein-protein interactions drive many biological processes, including the detection of phytopathogens by plants' R-Proteins and cell surface receptors. Many machine learning studies have attempted to predict protein-protein interactions…

Machine Learning · Computer Science 2023-10-24 Ruth Veevers , Dan MacLean

Numerical simulation is powerful to study nonlinear solid mechanics problems. However, mesh-based or particle-based numerical methods suffer from the common shortcoming of being time-consuming, particularly for complex problems with…

Machine Learning · Statistics 2024-09-18 Ming-Jian Li , Yanping Lian , Zhanshan Cheng , Lehui Li , Zhidong Wang , Ruxin Gao , Daining Fang

Quantifying the impacts of air pollution on health and climate relies on key atmospheric particle properties such as toxicity and hygroscopicity. However, these properties typically require complex observational techniques or expensive…

Machine Learning · Computer Science 2026-02-13 Fei Jiang , Jiyang Xia , Junjie Yu , Mingfei Sun , Hugh Coe , David Topping , Dantong Liu , Zhenhui Jessie Li , Zhonghua Zheng