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Noninvasive reconstruction of cardiac transmembrane potential (TMP) from surface electrocardiograms (ECG) involves an ill-posed inverse problem. Model-constrained regularization is powerful for incorporating rich physiological knowledge…
Diffusion models have recently gained immense interest for their generative capabilities, specifically the high quality and diversity of the synthesized data. However, examples of their applications in 3D medical imaging are still scarce,…
Healthcare requires AI that is predictive, reliable, and data-efficient. However, recent generative models lack physical foundation and temporal reasoning required for clinical decision support. As scaling language models show diminishing…
Conditional video diffusion models (CDM) have shown promising results for video synthesis, potentially enabling the generation of realistic echocardiograms to address the problem of data scarcity. However, current CDMs require a paired…
Recently, spatiotemporal graphs have emerged as a concise and elegant manner of representing video clips in an object-centric fashion, and have shown to be useful for downstream tasks such as action recognition. In this work, we investigate…
Artificial intelligence (AI) is poised to transform healthcare by enabling personalized and efficient care through data-driven insights. Although radiology is at the forefront of AI adoption, in practice, the potential of AI models is often…
Human anatomy, morphology, and associated diseases can be studied using medical imaging data. However, access to medical imaging data is restricted by governance and privacy concerns, data ownership, and the cost of acquisition, thus…
We present CardiacGen, a Deep Learning framework for generating synthetic but physiologically plausible cardiac signals like ECG. Based on the physiology of cardiovascular system function, we propose a modular hierarchical generative model…
Generating virtual populations of anatomy that capture sufficient variability while remaining plausible is essential for conducting in-silico trials of medical devices. However, not all anatomical shapes of interest are always available for…
We present a novel alignment-before-generation approach to tackle the challenging task of generating general 3D shapes based on 2D images or texts. Directly learning a conditional generative model from images or texts to 3D shapes is prone…
The development of high-dimensional generative models has recently gained a great surge of interest with the introduction of variational auto-encoders and generative adversarial neural networks. Different variants have been proposed where…
Conditional medical image generation plays an important role in many clinically relevant imaging tasks. However, existing methods still face a fundamental challenge in balancing inference efficiency, patient-specific fidelity, and…
We introduce deep neural networks for the analysis of anatomical shapes that learn a low-dimensional shape representation from the given task, instead of relying on hand-engineered representations. Our framework is modular and consists of…
Generative models have achieved success in producing apparently coherent 2D videos, but remain challenging in the physical world due to lack of 4D spatiotemporal scale. Typically, existing 4D generative models directly embed macro scale…
Echocardiography video is a primary modality for diagnosing heart diseases, but the limited data poses challenges for both clinical teaching and machine learning training. Recently, video generative models have emerged as a promising…
Synthetic cardiac MRI (CMRI) generation has emerged as a promising strategy to overcome the scarcity of annotated medical imaging data. Recent advances in GANs, VAEs, diffusion probabilistic models, and flow-matching techniques aim to…
Generative adversarial networks (GANs) have provided promising data enrichment solutions by synthesizing high-fidelity images. However, generating large sets of labeled images with new anatomical variations remains unexplored. We propose a…
We present the first image-based generative model of people in clothing for the full body. We sidestep the commonly used complex graphics rendering pipeline and the need for high-quality 3D scans of dressed people. Instead, we learn…
Patient-specific computational models of the heart are powerful tools for cardiovascular research and medicine, with demonstrated applications in treatment planning, device evaluation, and surgical decision-making. Yet constructing such…
Conditioning image generation on specific features of the desired output is a key ingredient of modern generative models. However, existing approaches lack a general and unified way of representing structural and semantic conditioning at…