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Neural Quantum States (NQS) are a class of variational wave functions parametrized by neural networks (NNs) to study quantum many-body systems. In this work, we propose \texttt{SineKAN}, a NQS \textit{ansatz} based on Kolmogorov-Arnold…

Massive mechanical resonators operating at the quantum scale can enable a large variety of applications in quantum technologies, as well as fundamental tests of quantum theory. Of crucial importance in that direction, is both their…

Quantum Physics · Physics 2019-12-04 Marios Kounalakis , Yaroslav M. Blanter , Gary A. Steele

Can a scientific simulation system be physically consistent, interpretable by design, and scalable across regimes--all at once? Despite decades of progress, this trifecta remains elusive. Classical methods like Kinetic Monte Carlo ensure…

Artificial Intelligence · Computer Science 2025-07-02 Qi Li , Kun Li , Haozhi Han , Honghui Shang , Xinfu He , Yunquan Zhang , Hong An , Ting Cao , Mao Yang

While noise is generally associated with uncertainties and often has a negative connotation in engineering, living organisms have evolved to adapt to (and even exploit) such uncertainty to ensure the survival of a species or implement…

Molecular Networks · Quantitative Biology 2022-09-29 Corentin Briat , Mustafa Khammash

We simulate the nonequilibrium steady state \textit{cis-trans} photoisomerization of retinal chromophore in rhodopsin based on a two-state-two-mode model coupled to a thermal environment. By analyzing the systematic trends within an…

Chemical Physics · Physics 2022-04-25 Chern Chuang , Paul Brumer

We propose a Kron-based model-order reduction method for mass-action kinetics chemical reaction networks (CRN) with constant inflow and proportional outflow. The reduced-order models preserve the CRN structure and we establish that the…

Systems and Control · Electrical Eng. & Systems 2022-04-12 Mohamad Agung Prawira Negara , Azka Muji Burohman , Bayu Jayawardhana

We introduce a stochastic model describing aggregation of misfolded proteins and degradation by the protein quality control system in a single cell. In analogy with existing literature, aggregates can grow, nucleate and fragment…

Cell Behavior · Quantitative Biology 2012-07-06 Simone Pigolotti , Ludvig Lizana , Daniel Otzen , Kim Sneppen

Neural network quantum states (NQS) have emerged as a powerful and flexible framework for addressing quantum many-body problems. While successful for model Hamiltonians, their application to molecular systems remains challenging for several…

Chemical Physics · Physics 2025-07-28 Zibo Wu , Bohan Zhang , Wei-Hai Fang , Zhendong Li

Biochemical oscillations are prevalent in living organisms. Systems with a small number of constituents cannot sustain coherent oscillations for an indefinite time because of fluctuations in the period of oscillation. We show that the…

Statistical Mechanics · Physics 2017-06-29 Andre C Barato , Udo Seifert

Noise-enhanced applications in open quantum walk (QW) have recently seen a surge due to their ability to improve performance. However, verifying the success of open QW is challenging, as mixed-state tomography is a resource-intensive…

We numerically and experimentally achieve quasi-bound states in the continuums (BICs) with high-Q factors in the free-standing metal complementary periodic cross-shaped resonators (CPCRs) at terahertz (THz) frequencies. Such induced…

Optics · Physics 2020-07-17 Dejun Liu , Feng Wu , Lin Chen , Feng Liu

A brain-computer interface (BCI) system enables direct communication between the brain and external devices, offering significant potential for assistive technologies and advanced human-computer interaction. Despite progress, BCI systems…

Quantum Physics · Physics 2025-05-21 Bikash K. Behera , Saif Al-Kuwari , Ahmed Farouk

Neural-Network Quantum State (NQS) has attracted significant interests as a powerful wave-function ansatz to model quantum phenomena. In particular, a variant of NQS based on the restricted Boltzmann machine (RBM) has been adapted to model…

Quantum Physics · Physics 2019-12-09 Chang-yu Hsieh , Qiming Sun , Shengyu Zhang , Chee Kong Lee

Recent advances in artificial intelligence have highlighted the remarkable capabilities of neural network (NN)-powered systems on classical computers. However, these systems face significant computational challenges that limit scalability…

Quantum Physics · Physics 2026-05-08 Erik L. Connerty , Ethan N. Evans , Gerasimos Angelatos , Vignesh Narayanan

We extend the linear mixed-effects state model to accommodate the correlated individuals and investigate its parameter and state estimation based on disturbance smoothing in this paper. For parameter estimation, EM and score based…

Methodology · Statistics 2014-09-03 Jie Zhou , Aiping Tang

Stochasticity plays a fundamental role in various biochemical processes, such as cell regulatory networks and enzyme cascades. Isothermal, well-mixed systems can be modelled as Markov processes, typically simulated using the Gillespie…

Molecular Networks · Quantitative Biology 2016-10-12 Andrew Duncan , Radek Erban , Konstantinos Zygalakis

In Refs. [Phys. Rev. A 96, 062303 (2017)] and [Sci. China Phys. Mech. Astron. 61, 70311 (2018)], the authors reported an algorithm to simulate, in a circuit-based quantum computer, a general quantum channel (QC). However, the application of…

Quantum Physics · Physics 2023-05-03 Marcelo S. Zanetti , Douglas F. Pinto , Marcos L. W. Basso , Jonas Maziero

The dynamics of cellular aggregates is driven by the interplay of mechanochemical processes and cellular activity. Although deterministic models may capture mechanical features, local chemical fluctuations trigger random cell responses,…

Soft Condensed Matter · Physics 2024-01-17 Ana Carpio , Elena Cebrian

Detailed modeling and simulation of biochemical systems is complicated by the problem of combinatorial complexity, an explosion in the number of species and reactions due to myriad protein-protein interactions and post-translational…

Quantitative Methods · Quantitative Biology 2014-05-20 Justin S. Hogg , Leonard A. Harris , Lori J. Stover , Niketh S. Nair , James R. Faeder

A novel approach to simulate simple protein-ligand systems at large time- and length-scales is to couple Markov state models (MSMs) of molecular kinetics with particle-based reaction-diffusion (RD) simulations, MSM/RD. Currently, MSM/RD…

Chemical Physics · Physics 2021-12-10 Mauricio J. del Razo , Manuel Dibak , Christof Schütte , Frank Noé
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