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During various stages of the COVID-19 pandemic, countries implemented diverse vaccine management approaches, influenced by variations in infrastructure and socio-economic conditions. This article provides a comprehensive overview of…

Optimization and Control · Mathematics 2024-05-27 Shibshankar Dey , Ali Kaan Kurbanzade , Esma S. Gel , Joseph Mihaljevic , Sanjay Mehrotra

Accurate models of clinical actions and their impacts on disease progression are critical for estimating personalized optimal dynamic treatment regimes (DTRs) in medical/health research, especially in managing chronic conditions.…

Methodology · Statistics 2021-02-19 William Hua , Hongyuan Mei , Sarah Zohar , Magali Giral , Yanxun Xu

A novel coronavirus disease has emerged (later named COVID-19) and caused the world to enter a new reality, with many direct and indirect factors influencing it. Some are human-controllable (e.g. interventional policies, mobility and the…

Machine Learning · Computer Science 2021-01-12 Haonan Wu , Rajarshi Banerjee , Indhumathi Venkatachalam , Daniel Percy-Hughes , Praveen Chougale

We examine here the effects of recurrent vaccination and waning immunity on the establishment of an endemic equilibrium in a population. An individual-based model that incorporates memory effects for transmission rate during infection and…

Populations and Evolution · Quantitative Biology 2024-11-22 Félix Foutel-Rodier , Arthur Charpentier , Hélène Guérin

More than ever COVID-19 is putting pressure on health systems all around the world, especially in Brazil. In this study we propose an analytical approach based on statistics and machine learning that uses lab exam data coming from patients…

Machine Learning · Computer Science 2020-11-09 Vitor Bezzan , Cleber D. Rocco

In this paper, we develop a Bayesian calendar-time survival model motivated by infectious disease prevention studies occurring during an epidemic, when the risk of infection can change rapidly as the epidemic curve shifts. For studies in…

Methodology · Statistics 2026-02-24 Angela M Dahl , Elizabeth R Brown

A popular perspective in Reinforcement learning (RL) casts the problem as probabilistic inference on a graphical model of the Markov decision process (MDP). The core object of study is the probability of each state-action pair being visited…

Machine Learning · Computer Science 2023-11-23 Jean Tarbouriech , Tor Lattimore , Brendan O'Donoghue

Misclassification in binary outcomes is not uncommon and statistical methods to investigate its impact on policy-driving study results are lacking. While misclassifying binary outcomes is a statistically ubiquitous phenomena, we focus on…

Qatar has undergone distinct waves of COVID-19 infections, compounded by the emergence of variants, posing additional complexities. This research uniquely delves into the varied efficacy of existing vaccines and the pivotal role of…

Applications · Statistics 2023-12-29 Elizabeth Amona , Indranil Sahoo , Edward Boone , Ryad Ghanam

Incorporating social factors into disease prevention and control efforts is an important undertaking of behavioral epidemiology. The interplay between disease transmission and human health behaviors, such as vaccine uptake, results in…

Physics and Society · Physics 2023-02-16 Marzena Fügenschuh , Feng Fu

Static supervised learning-in which experimental data serves as a training sample for the estimation of an optimal treatment assignment policy-is a commonly assumed framework of policy learning. An arguably more realistic but challenging…

Econometrics · Economics 2024-09-04 Toru Kitagawa , Jeff Rowley

Vaccination has played an important role in preventing the spread of infectious diseases. However, the limited availability of vaccines and personnel at the roll-out of a new vaccine and the costs of vaccination campaigns often limit how…

Physics and Society · Physics 2026-01-27 Rowan Hoogervorst , Evelien van der Hurk , David Pisinger

Applying causal inference models in areas such as economics, healthcare and marketing receives great interest from the machine learning community. In particular, estimating the individual-treatment-effect (ITE) in settings such as precision…

Machine Learning · Computer Science 2019-10-17 Jeroen Berrevoets , Sam Verboven , Wouter Verbeke

Combating an epidemic entails finding a plan that describes when and how to apply different interventions, such as mask-wearing mandates, vaccinations, school or workplace closures. An optimal plan will curb an epidemic with minimal loss of…

Machine Learning · Computer Science 2023-06-08 Anh Mai , Nikunj Gupta , Azza Abouzied , Dennis Shasha

Early-phase clinical trials face the challenge of selecting optimal drug doses that balance safety and efficacy due to uncertain dose-response relationships and varied participant characteristics. Traditional randomized dose allocation…

Methodology · Statistics 2026-02-13 Rohit Kanrar , Chunlin Li , Zara Ghodsi , Margaret Gamalo

To curb the spread of COVID-19, many governments around the world have implemented tiered lockdowns with varying degrees of stringency. Lockdown levels are typically increased when the disease spreads and reduced when the disease abates. A…

Populations and Evolution · Quantitative Biology 2020-11-16 Laurentz E. Olivier , Stefan Botha , Ian K. Craig

Understanding how to effectively control an epidemic spreading on a network is a problem of paramount importance for the scientific community. The ongoing COVID-19 pandemic has highlighted the need for policies that mitigate the spread,…

Populations and Evolution · Quantitative Biology 2021-09-14 Carlo Cenedese , Lorenzo Zino , Michele Cucuzzella , Ming Cao

A mathematical model for the COVID-19 pandemic spread, which integrates age-structured Susceptible-Exposed-Infected-Recovered-Deceased dynamics with real mobile phone data accounting for the population mobility, is presented. The dynamical…

Applications · Statistics 2021-08-24 Ritabrata Dutta , Susana Gomes , Dante Kalise , Lorenzo Pacchiardi

We consider a multi-armed bandit setting with finitely many arms, in which each arm yields an $M$-dimensional vector reward upon selection. We assume that the reward of each dimension (a.k.a. {\em objective}) is generated independently of…

Machine Learning · Computer Science 2025-01-24 Zhirui Chen , P. N. Karthik , Yeow Meng Chee , Vincent Y. F. Tan

Algorithmic predictions are emerging as a promising solution concept for efficiently allocating societal resources. Fueling their use is an underlying assumption that such systems are necessary to identify individuals for interventions. We…

Machine Learning · Computer Science 2024-06-21 Ali Shirali , Rediet Abebe , Moritz Hardt