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We study the optimal control problem of a free boundary PDE model describing the growth of multilayered tumor tissue in vitro. We seek the optimal amount of tumor growth inhibitor that simultaneously minimizes the thickness of the tumor…

Analysis of PDEs · Mathematics 2024-10-21 Xinyue Evelyn Zhao , Yixiang Wu , Rachel Leander , Wandi Ding , Suzanne Lenhart

We show how a fixed point based boundary-layer analysis technique can be used to obtain the steady-state particle density profiles of driven exclusion processes on two-lane systems with open boundaries. We have considered two distinct…

Statistical Mechanics · Physics 2015-06-11 Vandana Yadav , Rajesh Singh , Sutapa Mukherji

This paper concerns the free boundary problem of an epidemic model. The spatial movements of the infectious agents and the infective humans are approximated by nonlocal diffusion operators. Especially, both the growth rate of the agents and…

Analysis of PDEs · Mathematics 2024-06-11 Xueping Li , Lei Li , Mingxin Wang

Biofilms are ubiquitous macro-colonies of bacteria that develop at various interfaces (solid-liquid, solid-gas or liquid-gas). The formation of biofilms starts with the attachment of individual bacteria to an interface, where they…

Biological Physics · Physics 2016-11-03 Sarah Trinschek , Karin John , Uwe Thiele

We consider an epidemic model with nonlocal diffusion and free boundaries, which describes the evolution of an infectious agents with nonlocal diffusion and the infected humans without diffusion, where humans get infected by the agents, and…

Analysis of PDEs · Mathematics 2019-12-06 Meng Zhao , Yang Zhang , Wan-Tong Li , Yihong Du

The cell motility problem has been investigated for a long time. Today, many biologists, physicists, and mathematicians are looking for new research instruments for this process. A simple 2D model of a free-boundary cell moving on a…

Cell Behavior · Quantitative Biology 2024-01-03 Vitaly Chernik , Pavel Buklemishev

A model for ionic and electronic grain boundary transport through thin films, scales or membranes with columnar grain structure is introduced. The grain structure is idealized as a lattice of identical hexagonal cells - a honeycomb pattern.…

Materials Science · Physics 2017-05-05 M. P. Tautschnig , N. M. Harrison , M. W. Finnis

This paper studies asymptotic behavior of solutions of a free boundary problem modeling the growth of tumors with two species of cells: proliferating cells and quiecent cells. In previous literatures it has been proved that this problem has…

Analysis of PDEs · Mathematics 2013-03-18 Shangbin Cui

We study a two-dimensional free boundary problem that models motility of eukaryotic cells on substrates. This problem consists of an elliptic equation describing the flow of cytoskeleton gel coupled with a convection-diffusion PDE for the…

Analysis of PDEs · Mathematics 2017-07-12 Leonid Berlyand , Jan Fuhrmann , Volodymyr Rybalko

We attempt to describe surface defects in smectic A thin films by formulating a free discontinuity problem - that is, a variational problem in which the order parameter is allowed to have jump discontinuities on some (unknown) set. The free…

Analysis of PDEs · Mathematics 2023-03-10 John M. Ball , Giacomo Canevari , Bianca Stroffolini

The amplification of an external signal is a key step in direction sensing of biological cells. We consider a simple model for the response to a time-depending signal, which was previously proposed by the last three authors. The model…

Analysis of PDEs · Mathematics 2020-06-30 Anna Logioti , Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

This paper involves a diffusive epidemic model whose domain has one free boundary with the Stefan boundary condition, and one fixed boundary subject to the usual homogeneous Dirichlet or Neumann condition. By using the standard upper and…

Analysis of PDEs · Mathematics 2024-05-03 Xueping Li , Lei Li , Ying Xu , DanDan Zhu

We present a collision model for phase-resolved Direct Numerical Simulations of sediment transport that couple the fluid and particles by the Immersed Boundary Method. Typically, a contact model for these types of simulations comprises a…

Fluid Dynamics · Physics 2017-04-18 Edward Biegert , Bernhard Vowinckel , Eckart Meiburg

In this paper, we present a continuum model for the dynamics of low angle grain boundaries in two dimensions based on the motion of constituent dislocations of the grain boundaries. The continuum model consists of an equation for the motion…

Materials Science · Physics 2018-06-13 Luchan Zhang , Yang Xiang

The theory of degenerate parabolic equations of the forms \[ u_t=(\Phi(u_x))_{x} \quad {\rm and} \quad v_{t}=(\Phi(v))_{xx} \] is used to analyze the process of contour enhancement in image processing, based on the evolution model of…

Dynamical Systems · Mathematics 2007-05-23 G. I. Barenblatt , J. L. Vazquez

This paper studies the boundary behaviour at mechanical equilibrium at the ends of a finite interval of a class of systems of interacting particles with monotone decreasing repulsive force. Our setting covers pile-ups of dislocations,…

Analysis of PDEs · Mathematics 2016-09-13 Cameron Hall , Thomas Hudson , Patrick van Meurs

The use of thin liquid films has expanded beyond lubrication and coatings, and into applications in actuators and adaptive optical elements. In contrast to their predecessors, whose dynamics can be typically captured by modelling infinite…

Fluid Dynamics · Physics 2023-07-06 Israel Gabay , Vesna Bacheva , Dotan Ilssar , Moran Bercovici , Antonio Ramos , Amir Gat

In this paper we study a linearized eigenvalue problem derived from a a free boundary problem modeling the growth of a tumor containing two species of cells: proliferating cells and quiescent cells. The reduced form of this eigenvalue…

Analysis of PDEs · Mathematics 2018-10-19 Shangbin Cui , Jiayue Zheng

A new method for the solution of initial-boundary value problems for evolution PDEs recently introduced by Fokas is generalised to multidimensions. Also the relation of this method with the method of images and with the classical integral…

Condensed Matter · Physics 2007-05-23 Athanassios S. Fokas , Daniel ben-Avraham

We prove local existence for classical solutions of a free boundary problem which arises in one of the biological selection models proposed by Brunet and Derrida, [2] and Durrett and Remenik, [14]. The problem we consider describes the…

Probability · Mathematics 2018-08-09 Jimyeong Lee
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