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Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Machine Learning · Statistics 2018-06-28 Jens Behrmann , Christian Etmann , Tobias Boskamp , Rita Casadonte , Jörg Kriegsmann , Peter Maass

Cancer is one of the most dangerous diseases to humans, and yet no permanent cure has been developed for it. Breast cancer is one of the most common cancer types. According to the National Breast Cancer foundation, in 2020 alone, more than…

Image and Video Processing · Electrical Eng. & Systems 2022-03-10 Ali Bou Nassif , Manar Abu Talib , Qassim Nasir , Yaman Afadar , Omar Elgendy

Reconstruction of gene regulatory networks is the process of identifying gene dependency from gene expression profile through some computation techniques. In our human body, though all cells pose similar genetic material but the activation…

Cancer disease occurs because of a disorder in the cellular regulatory mechanism, Which causes cellular malformation. The genes that start the malformation are called Cancer driver genes (CDGs) . Numerous computational methods have been…

Molecular Networks · Quantitative Biology 2020-12-16 Mostafa Akhavan Safar , Babak Teimourpour , Mehrdad Kargari

Skin cancer is a fatal manifestation of cancer. Unrepaired deoxyribo-nucleic acid (DNA) in skin cells, causes genetic defects in the skin and leads to skin cancer. To deal with lethal mortality rates coupled with skyrocketing costs of…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Sanya Sinha , Nilay Gupta

Breast cancer is the most common cancer in the world and the most prevalent cause of death among women worldwide. Nevertheless, it is also one of the most treatable malignancies if detected early. In this paper, a deep convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Hussin Ragb , Redha Ali , Elforjani Jera , Nagi Buaossa

Advance in medical imaging is an important part in deep learning research. One of the goals of computer vision is development of a holistic, comprehensive model which can identify tumors from histology slides obtained via biopsies. A major…

Image and Video Processing · Electrical Eng. & Systems 2024-12-18 Vidit Gautam

In this proposed work, we identified the significant research issues on lung cancer risk factors. Capturing and defining symptoms at an early stage is one of the most difficult phases for patients. Based on the history of patients records,…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Muhammad Sohaib , Mary Adewunmi

Genomic alterations lead to cancer complexity and form a major hurdle for a comprehensive understanding of the molecular mechanisms underlying oncogenesis. In this review, we describe the recent advances in studying cancer-associated genes…

Molecular Networks · Quantitative Biology 2007-12-24 Edwin Wang , Anne Lenferink , Maureen O'Connor-McCourt

In biological research machine learning algorithms are part of nearly every analytical process. They are used to identify new insights into biological phenomena, interpret data, provide molecular diagnosis for diseases and develop…

The incidence of malignant melanoma continues to increase worldwide. This cancer can strike at any age; it is one of the leading causes of loss of life in young persons. Since this cancer is visible on the skin, it is potentially detectable…

Computer Vision and Pattern Recognition · Computer Science 2016-01-29 Nabin K. Mishra , M. Emre Celebi

Cancer is one of the leading cause of death, worldwide. Many believe that genomic data will enable us to better predict the survival time of these patients, which will lead to better, more personalized treatment options and patient care. As…

Machine Learning · Computer Science 2019-11-19 Luke Kumar , Russell Greiner

Breast cancer ranks as the most prevalent form of cancer diagnosed in women, and diagnosis faces several challenges, a change in the size, shape and appearance of breasts, dense breast tissue, lumps or thickening in the breast especially if…

Image and Video Processing · Electrical Eng. & Systems 2023-12-12 Abdulqader Mohammed , Mohammed Abdel Razek , Mohamed El-dosuky , Ahmed Sobhi

Melanoma is one of the ten most common cancers in the US. Early detection is crucial for survival, but often the cancer is diagnosed in the fatal stage. Deep learning has the potential to improve cancer detection rates, but its…

Computer Vision and Pattern Recognition · Computer Science 2019-05-16 Devansh Bisla , Anna Choromanska , Jennifer A. Stein , David Polsky , Russell Berman

Complex gene interactions play a significant role in cancer progression, driving cellular behaviors that contribute to tumor growth, invasion, and metastasis. Gene co-expression networks model the functional connectivity between genes under…

Molecular Networks · Quantitative Biology 2024-11-27 Radwa Adel , Ercan Engin Kuruoglu

Machine learning (ML) approaches have been used to develop highly accurate and efficient applications in many fields including bio-medical science. However, even with advanced ML techniques, cancer classification using gene expression data…

Genomics · Quantitative Biology 2023-05-10 Mahmood Khalsan , Mu Mu , Eman Salih Al-Shamery , Lee Machado , Suraj Ajit , Michael Opoku Agyeman

Microarray data are often used to determine which genes are differentially expressed between groups, for example, between treatment and control groups. There are methods of determining which genes have a high probability of differential…

Quantitative Methods · Quantitative Biology 2007-05-23 David R. Bickel

Cancer progresses with a change in the structure of the gene network in normal cells. We define a measure of organizational hierarchy in gene networks of affected cells in adult acute myeloid leukemia (AML) patients. With a retrospective…

Tissues and Organs · Quantitative Biology 2015-06-23 Shubham Tripathi , Michael W. Deem

In this paper we discuss a new method for detecting leukemia in microscopic blood smear images using deep neural networks to diagnose leukemia early in blood. leukemia is considered one of the most dangerous mortality causes for a human…

Image and Video Processing · Electrical Eng. & Systems 2023-01-10 Abdelmageed Ahmed , Alaa Nagy , Ahmed Kamal , Daila Farghl

We have analyzed gene expression data from 3 different kinds of samples: normal human tissues, human cancer cell lines and leukemic cells from lymphoid and myeloid leukemia pediatric patients. We have searched for genes that are over…

Tissues and Organs · Quantitative Biology 2009-11-11 Joseph Lotem , Dvir Netanely , Eytan Domany , Leo Sachs
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