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Related papers: ProtST: Multi-Modality Learning of Protein Sequenc…

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Emotion recognition in speech presents a complex multimodal challenge, requiring comprehension of both linguistic content and vocal expressivity, particularly prosodic features such as fundamental frequency, intensity, and temporal…

Performance prediction is a method to estimate the performance of Language Models (LMs) on various Natural Language Processing (NLP) tasks, mitigating computational costs associated with model capacity and data for fine-tuning. Our paper…

Computation and Language · Computer Science 2024-12-17 David Anugraha , Genta Indra Winata , Chenyue Li , Patrick Amadeus Irawan , En-Shiun Annie Lee

Determining the different conformational states of a protein and the transition paths between them is key to fully understanding the relationship between biomolecular structure and function. This can be accomplished by sampling protein…

Biological Physics · Physics 2021-03-24 Venkata K. Ramaswamy , Chris G. Willcocks , Matteo T. Degiacomi

Representation learning on heterogeneous text-rich networks (HTRNs), which consist of multiple types of nodes and edges with each node associated with textual information, is essential for various real-world applications. Given the success…

Machine Learning · Computer Science 2025-01-23 Qiuyu Zhu , Liang Zhang , Qianxiong Xu , Cheng Long

Proteins play a pivotal role in biological systems. The use of machine learning algorithms for protein classification can assist and even guide biological experiments, offering crucial insights for biotechnological applications. We…

Quantitative Methods · Quantitative Biology 2024-10-24 Yizheng Wang , Yixiao Zhai , Yijie Ding , Quan Zou

Despite recent success in machine reading comprehension (MRC), learning high-quality MRC models still requires large-scale labeled training data, even using strong pre-trained language models (PLMs). The pre-training tasks for PLMs are not…

Computation and Language · Computer Science 2021-07-20 Ning Bian , Xianpei Han , Bo Chen , Hongyu Lin , Ben He , Le Sun

While protein language models (PLMs) are one of the most promising avenues of research for future de novo protein design, the way in which they transform sequences to hidden representations, as well as the information encoded in such…

Machine Learning · Computer Science 2026-05-29 Kosio Beshkov , Anders Malthe-Sørenssen

Pretrained language models (PLMs) have produced substantial improvements in discourse-aware neural machine translation (NMT), for example, improved coherence in spoken language translation. However, the underlying reasons for their strong…

Computation and Language · Computer Science 2023-06-01 Zhihong Huang , Longyue Wang , Siyou Liu , Derek F. Wong

Multimodal large language models (MLLMs) have shown remarkable performance in vision-language tasks. However, existing MLLMs are primarily trained on generic datasets, limiting their ability to reason on domain-specific visual cues such as…

Computer Vision and Pattern Recognition · Computer Science 2025-07-15 Hatef Otroshi Shahreza , Sébastien Marcel

Integrating image and text data through multi-modal learning has emerged as a new approach in medical imaging research, following its successful deployment in computer vision. While considerable efforts have been dedicated to establishing…

Computer Vision and Pattern Recognition · Computer Science 2024-09-09 Fereshteh Shakeri , Yunshi Huang , Julio Silva-Rodríguez , Houda Bahig , An Tang , Jose Dolz , Ismail Ben Ayed

The diverse nature of protein prediction tasks has traditionally necessitated specialized models, hindering the development of broadly applicable and computationally efficient Protein Language Models (PLMs). In this work, we introduce…

For continual learning, text-prompt-based methods leverage text encoders and learnable prompts to encode semantic features for sequentially arrived classes over time. A common challenge encountered by existing works is how to learn unique…

Computer Vision and Pattern Recognition · Computer Science 2026-04-02 Jie Mei , Li-Leng Peng , Keith Fuller , Jenq-Neng Hwang

Fine-tuned pre-trained language models (PLMs) have achieved awesome performance on almost all NLP tasks. By using additional prompts to fine-tune PLMs, we can further stimulate the rich knowledge distributed in PLMs to better serve…

Computation and Language · Computer Science 2021-09-16 Xu Han , Weilin Zhao , Ning Ding , Zhiyuan Liu , Maosong Sun

This paper aims to retrieve proteins with similar structures and semantics from large-scale protein dataset, facilitating the functional interpretation of protein structures derived by structural determination methods like cryo-Electron…

Biomolecules · Quantitative Biology 2025-06-11 Qifeng Wu , Zhengzhe Liu , Han Zhu , Yizhou Zhao , Daisuke Kihara , Min Xu

We introduce a novel continued pre-training method, MELT (MatEriaLs-aware continued pre-Training), specifically designed to efficiently adapt the pre-trained language models (PLMs) for materials science. Unlike previous adaptation…

Computation and Language · Computer Science 2024-10-22 Junho Kim , Yeachan Kim , Jun-Hyung Park , Yerim Oh , Suho Kim , SangKeun Lee

Protein representation learning methods have shown great potential to yield useful representation for many downstream tasks, especially on protein classification. Moreover, a few recent studies have shown great promise in addressing…

Machine Learning · Computer Science 2023-04-11 Can Chen , Jingbo Zhou , Fan Wang , Xue Liu , Dejing Dou

Pre-trained Language Models (PLMs) have achieved remarkable performance for various language understanding tasks in IR systems, which require the fine-tuning process based on labeled training data. For low-resource scenarios, prompt-based…

Computation and Language · Computer Science 2022-04-04 Ziyun Xu , Chengyu Wang , Minghui Qiu , Fuli Luo , Runxin Xu , Songfang Huang , Jun Huang

Prompt tuning and adapter tuning have shown great potential in transferring pre-trained vision-language models (VLMs) to various downstream tasks. In this work, we design a new type of tuning method, termed as regularized mask tuning, which…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Kecheng Zheng , Wei Wu , Ruili Feng , Kai Zhu , Jiawei Liu , Deli Zhao , Zheng-Jun Zha , Wei Chen , Yujun Shen

At the intersection of the rapidly growing biological data landscape and advancements in Natural Language Processing (NLP), protein language models (PLMs) have emerged as a transformative force in modern research. These models have achieved…

Biomolecules · Quantitative Biology 2025-02-12 Lei Wang , Xudong Li , Han Zhang , Jinyi Wang , Dingkang Jiang , Zhidong Xue , Yan Wang

Accurately modeling the protein fitness landscapes holds great importance for protein engineering. Recently, due to their capacity and representation ability, pre-trained protein language models have achieved state-of-the-art performance in…

Biomolecules · Quantitative Biology 2024-02-06 Ziyi Zhou , Liang Zhang , Yuanxi Yu , Mingchen Li , Liang Hong , Pan Tan
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