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Discovering the 3D atomic structure of molecules such as proteins and viruses is a fundamental research problem in biology and medicine. Electron Cryomicroscopy (Cryo-EM) is a promising vision-based technique for structure estimation which…

Computer Vision and Pattern Recognition · Computer Science 2016-11-18 Marcus A. Brubaker , Ali Punjani , David J. Fleet

We consider the problem of positioning a cloud of points in the Euclidean space $\mathbb{R}^d$, using noisy measurements of a subset of pairwise distances. This task has applications in various areas, such as sensor network localization and…

Statistics Theory · Mathematics 2012-11-22 Adel Javanmard , Andrea Montanari

Electron tomography has achieved higher resolution and quality at reduced doses with recent advances in compressed sensing. Compressed sensing (CS) theory exploits the inherent sparse signal structure to efficiently reconstruct…

Computational Physics · Physics 2020-12-02 Jonathan Schwartz , Huihuo Zheng , Marcus Hanwell , Yi Jiang , Robert Hovden

Computer-generated holograms (CGHs) are used in holographic three-dimensional (3D) displays and holographic projections. The quality of the reconstructed images using phase-only CGHs is degraded because the amplitude of the reconstructed…

Computer Vision and Pattern Recognition · Computer Science 2022-02-02 Yoshiyuki Ishii , Tomoyoshi Shimobaba , David Blinder , Tobias Birnbaum , Peter Schelkens , Takashi Kakue , Tomoyoshi Ito

Highly multiplexed microscopy enables rich spatial characterization of tissues at single-cell resolution, yet most analyses rely on two-dimensional sections despite inherently three-dimensional tissue organization. Acquiring dense…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Ido Harlev , Tamar Oukhanov , Raz Ben-Uri , Leeat Keren , Shai Bagon

In computer graphics, smooth data reconstruction on 2D or 3D manifolds usually refers to subdivision problems. Such a method is only valid based on dense sample points. The manifold usually needs to be triangulated into meshes (or patches)…

Numerical Analysis · Mathematics 2011-05-30 Li Chen , Feng Luo

Automatic 3D neuron reconstruction is critical for analysing the morphology and functionality of neurons in brain circuit activities. However, the performance of existing tracing algorithms is hinged by the low image quality. Recently, a…

Image and Video Processing · Electrical Eng. & Systems 2021-09-17 Heng Wang , Chaoyi Zhang , Jianhui Yu , Yang Song , Siqi Liu , Wojciech Chrzanowski , Weidong Cai

The ability to gain insights into the 3D properties of artificial or biological systems is often critical. However, 3D structures are difficult to retrieve at low dose and with extremely fast processing, as most techniques are based on…

Image and Video Processing · Electrical Eng. & Systems 2019-09-11 J. Duarte , R. Cassin , J. Huijts , M. Kholodtsova , B. Iwan , M. Kovacev , M. Fajardo , F. Fortuna , L. Delbecq , W. Boutu , H. Merdji

We live in a period where bio-informatics is rapidly expanding, a significant quantity of genomic data has been produced as a result of the advancement of high-throughput genome sequencing technology, raising concerns about the costs…

Quantitative Methods · Quantitative Biology 2023-03-10 Mehedi Hasan Sarkar , Adnan Ferdous Ashrafi

Modeling the 3D structures of cells and tissues is crucial in biology. Sequential cross-sectional images from electron microscopy provide high-resolution intracellular structure information. The segmentation of complex cell structures…

Quantitative Methods · Quantitative Biology 2025-02-14 Jin Kousaka , Atsuko H. Iwane , Yuichi Togashi

We present a novel method for reconstructing clothed humans from a sparse set of, e.g., 1 to 6 RGB images. Despite impressive results from recent works employing deep implicit representation, we revisit the volumetric approach and…

Computer Vision and Pattern Recognition · Computer Science 2023-07-26 Sicong Tang , Guangyuan Wang , Qing Ran , Lingzhi Li , Li Shen , Ping Tan

In this study we explore the possibility to use deep learning for the reconstruction of phase images from 4D scanning transmission electron microscopy (4D-STEM) data. The process can be divided into two main steps. First, the complex…

Materials Science · Physics 2023-02-15 Thomas Friedrich , Chu-Ping Yu , Jo Verbeeck , Sandra Van Aert

Reconstructing 3D human heads in low-view settings presents technical challenges, mainly due to the pronounced risk of overfitting with limited views and high-frequency signals. To address this, we propose geometry decomposition and adopt a…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Baixin Xu , Jiarui Zhang , Kwan-Yee Lin , Chen Qian , Ying He

Learning meaningful protein representation is important for a variety of biological downstream tasks such as structure-based drug design. Having witnessed the success of protein sequence pretraining, pretraining for structural data which is…

Machine Learning · Computer Science 2023-02-23 Yufei Huang , Lirong Wu , Haitao Lin , Jiangbin Zheng , Ge Wang , Stan Z. Li

Recently, a lot of attention has been focused on the incorporation of 3D data into face analysis and its applications. Despite providing a more accurate representation of the face, 3D facial images are more complex to acquire than 2D…

Computer Vision and Pattern Recognition · Computer Science 2021-03-01 Araceli Morales , Gemma Piella , Federico M. Sukno

Score-based generative models (SGMs) have recently shown promising results for image reconstruction on simulated positron emission tomography (PET) datasets. In this work we have developed and implemented practical methodology for 3D image…

This paper introduces a hybrid two-stage registration framework for reconstructing three-dimensional (3D) kidney anatomy from macroscopic slices, using CT-derived models as the geometric reference standard. The approach addresses the…

Image and Video Processing · Electrical Eng. & Systems 2026-02-17 Tomasz Les , Tomasz Markiewicz , Malgorzata Lorent , Miroslaw Dziekiewicz , Krzysztof Siwek

Differential phase-contrast computed tomography (DPC-CT) is a powerful analysis tool for soft-tissue and low-atomic-number samples. Limited by the implementation conditions, DPC-CT with incomplete projections happens quite often.…

Medical Physics · Physics 2020-07-01 Jianbing Dong , Jian Fu , Zhao He

Conventional 2-D scanning electron microscopy (SEM) is commonly used to rapidly and qualitatively evaluate membrane pore structure. Quantitative 2-D analyses of pore sizes can be extracted from SEM, but without information about 3-D spatial…

Realistic microscale domains are an essential step towards making modern multiscale simulations more applicable to computational materials engineering. For this purpose, 3D computed tomography scans can be very expensive or technically…