English
Related papers

Related papers: ADDIS-Graphs for online error control with applica…

200 papers

Controlling the false discovery rate (FDR) in variable selection becomes challenging when predictors are correlated, as existing methods often exclude all members of correlated groups and consequently perform poorly for prediction. We…

Methodology · Statistics 2026-03-03 Sarah Organ , Toby Kenney , Hong Gu

Adverse Drug Reactions (ADRs) are a leading cause of morbidity and mortality. Existing prediction methods rely mainly on chemical similarity, machine learning on structured databases, or isolated target profiles, but often fail to integrate…

Biomolecules · Quantitative Biology 2026-03-03 David Jackson , Michael Gertz , Jürgen Hesser

Multiple comparison procedures that control a family-wise error rate or false discovery rate provide an achieved error rate as the adjusted p-value for each hypothesis tested. However, since such p-values are not probabilities that the null…

Methodology · Statistics 2013-09-03 David R. Bickel

Intrusion detection systems (IDSs) generate valuable knowledge about network security, but an abundance of false alarms and a lack of methods to capture the interdependence among alerts hampers their utility for network defense. Here, we…

Cryptography and Security · Computer Science 2019-01-17 Anthony Palladino , Christopher J. Thissen

Multiple testing literature contains ample research on controlling false discoveries for hypotheses classified according to one criterion, which we refer to as one-way classified hypotheses. Although simultaneous classification of…

Methodology · Statistics 2019-03-12 Shinjini Nandi , Sanat K. Sarkar

Simultaneously performing variable selection and inference in high-dimensional regression models is an open challenge in statistics and machine learning. The increasing availability of vast amounts of variables requires the adoption of…

Methodology · Statistics 2025-05-08 Marco Molinari , Magne Thoresen

Primarily motivated by the drug development process, several publications have now presented methodology for the design of multi-arm multi-stage experiments with normally distributed outcome variables of known variance. Here, we extend…

Methodology · Statistics 2017-12-04 Michael Grayling , James Wason , Adrian Mander

We propose a general framework based on selectively traversed accumulation rules (STAR) for interactive multiple testing with generic structural constraints on the rejection set. It combines accumulation tests from ordered multiple testing…

Methodology · Statistics 2020-09-08 Lihua Lei , Aaditya Ramdas , William Fithian

Multiple hypothesis testing is a fundamental problem in high dimensional inference, with wide applications in many scientific fields. In genome-wide association studies, tens of thousands of tests are performed simultaneously to find if any…

Methodology · Statistics 2011-11-16 Jianqing Fan , Xu Han , Weijie Gu

A B testing serves as the gold standard for large scale, data driven decision making in online businesses. To mitigate metric variability and enhance testing sensitivity, control variates and regression adjustment have emerged as prominent…

Methodology · Statistics 2025-10-13 Yu Zhang , Bokui Wan , Yongli Qin

This article proposes novel rules for false discovery rate control (FDRC) geared towards online anomaly detection in time series. Online FDRC rules allow to control the properties of a sequence of statistical tests. In the context of…

Machine Learning · Statistics 2021-12-07 Quentin Rebjock , Barış Kurt , Tim Januschowski , Laurent Callot

A strength of parameterized algorithmics is that each problem can be parameterized by an essentially inexhaustible set of parameters. Usually, the choice of the considered parameter is informed by the theoretical relations between…

Computational Complexity · Computer Science 2026-05-05 Christian Komusiewicz , Nils Morawietz , Frank Sommer , Luca Pascal Staus

This paper studies the estimation of high dimensional Gaussian graphical model (GGM). Typically, the existing methods depend on regularization techniques. As a result, it is necessary to choose the regularized parameter. However, the…

Methodology · Statistics 2013-06-06 Weidong Liu

False discovery rate (FDR) control is a popular approach for maintaining the integrity of statistical analyses, especially in high-dimensional data settings, where multiple comparisons increase the risk of false positives. FDR control has…

Signal Processing · Electrical Eng. & Systems 2026-03-03 Fabian Scheidt , Jasin Machkour , Michael Muma

Recent advances in safety-critical risk-aware control are predicated on apriori knowledge of the disturbances a system might face. This paper proposes a method to efficiently learn these disturbances online, in a risk-aware context. First,…

Systems and Control · Electrical Eng. & Systems 2022-12-14 Prithvi Akella , Skylar X. Wei , Joel W. Burdick , Aaron D. Ames

Consider the problem of simultaneously testing null hypotheses H_1,...,H_s. The usual approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate (FWER), the probability of…

Statistics Theory · Mathematics 2007-06-13 E. L. Lehmann , Joseph P. Romano

This article considers the problem of multiple hypothesis testing using $t$-tests. The observed data are assumed to be independently generated conditional on an underlying and unknown two-state hidden model. We propose an asymptotically…

Statistics Theory · Mathematics 2011-02-22 Hongyuan Cao , Michael R. Kosorok

Fault diagnosis has attracted extensive attention for its importance in the exceedingly fault management framework for cloud virtualization, despite the fact that fault diagnosis becomes more difficult due to the increasing scalability and…

Software Engineering · Computer Science 2015-07-30 Ameen Alkasem , Hongwei Liu , Zuo Decheng , Yao Zhao

Many important tasks of large-scale recommender systems can be naturally cast as testing multiple linear forms for noisy matrix completion. These problems, however, present unique challenges because of the subtle bias-and-variance tradeoff…

Methodology · Statistics 2025-03-12 Wanteng Ma , Lilun Du , Dong Xia , Ming Yuan

The topic of multiple hypotheses testing now has a potpourri of novel theories and ubiquitous applications in diverse scientific fields. However, the universal utility of this field often hinders the possibility of having a generalized…

Statistics Theory · Mathematics 2025-04-25 Monitirtha Dey , Subir Kumar Bhandari