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The widespread misuse of image generation technologies has raised security concerns, driving the development of AI-generated image detection methods. However, generalization has become a key challenge and open problem: existing approaches…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Yongkang Hu , Yu Cheng , Yushuo Zhang , Yuan Xie , Zhaoxia Yin

Machine learning (ML) is revolutionising drug discovery by expediting the prediction of small molecule properties essential for developing new drugs. These properties -- including absorption, distribution, metabolism and excretion (ADME)--…

Machine Learning · Computer Science 2024-08-02 Alex G. C. de Sá , David B. Ascher

Engineering design optimization requires an efficient combination of a 3D shape representation, an optimization algorithm, and a design performance evaluation method, which is often computationally expensive. We present a prompt evolution…

Artificial Intelligence · Computer Science 2024-08-13 Melvin Wong , Thiago Rios , Stefan Menzel , Yew Soon Ong

Domain-specific Visually Rich Document Understanding (VRDU) presents significant challenges due to the complexity and sensitivity of documents in fields such as medicine, finance, and material science. Existing Large (Multimodal) Language…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Yihao Ding , Soyeon Caren Han , Yanbei Jiang , Yan Li , Zechuan Li , Yifan Peng

Machine learning approaches, enabled by the emergence of comprehensive databases of materials properties, are becoming a fruitful direction for materials analysis. As a result, a plethora of models have been constructed and trained on…

Statistical (machine learning) tools for equation discovery require large amounts of data that are typically computer generated rather than experimentally observed. Multiscale modeling and stochastic simulations are two areas where learning…

Machine Learning · Statistics 2021-03-17 Joseph Bakarji , Daniel M. Tartakovsky

The next generation of advanced materials is tending toward increasingly complex compositions. Synthesizing precise composition is time-consuming and becomes exponentially demanding with increasing compositional complexity. An experienced…

Materials Science · Physics 2024-03-12 Nathan Johnson , Aashwin Ananda Mishra , Apurva Mehta

Large Language Models (LLMs) show promise for equation discovery, yet their outputs are highly sensitive to prompt phrasing, a phenomenon we term instruction brittleness. Static prompts cannot adapt to the evolving state of a multi-step…

Machine Learning · Computer Science 2026-01-05 Junqi Qu , Yan Zhang , Shangqian Gao , Shibo Li

Developing advanced catalysts for acidic oxygen evolution reaction (OER) is crucial for sustainable hydrogen production. This study introduces a novel, multi-stage machine learning (ML) approach to streamline the discovery and optimization…

Materials Science · Physics 2024-07-09 Rui Ding , Jianguo Liu , Kang Hua , Xuebin Wang , Xiaoben Zhang , Minhua Shao , Yuxin Chen , Junhong Chen

Large-scale electrification is vital to addressing the climate crisis, but several scientific and technological challenges remain to fully electrify both the chemical industry and transportation. In both of these areas, new electrochemical…

Despite the remarkable code generation abilities of large language models LLMs, they still face challenges in complex task handling. Robot development, a highly intricate field, inherently demands human involvement in task allocation and…

Robotics · Computer Science 2024-02-19 Zhirong Luan , Yujun Lai , Rundong Huang , Xiaruiqi Lan , Liangjun Chen , Badong Chen

Molecular design and synthesis planning are two critical steps in the process of molecular discovery that we propose to formulate as a single shared task of conditional synthetic pathway generation. We report an amortized approach to…

Machine Learning · Computer Science 2022-03-15 Wenhao Gao , Rocío Mercado , Connor W. Coley

Self-driving labs are transforming drug discovery by enabling automated, AI-guided experimentation, but they face challenges in orchestrating complex workflows, integrating diverse instruments and AI models, and managing data efficiently.…

Software Engineering · Computer Science 2025-04-02 Yao Fehlis , Paul Mandel , Charles Crain , Betty Liu , David Fuller

Automated methods for discovering mechanistic simulator models from observational data offer a promising path toward accelerating scientific progress. Such methods often take the form of agentic-style iterative workflows that repeatedly…

Machine Learning · Computer Science 2026-02-23 Stefan Wahl , Raphaela Schenk , Ali Farnoud , Jakob H. Macke , Daniel Gedon

Training deep networks and tuning hyperparameters on large datasets is computationally intensive. One of the primary research directions for efficient training is to reduce training costs by selecting well-generalizable subsets of training…

In differential equation discovery algorithms, a priori expert knowledge is mainly used implicitly to constrain the form of the expected equation, making it impossible for the algorithm to truly discover equations. Instead, most…

Artificial Intelligence · Computer Science 2025-01-03 Elizaveta Ivanchik , Alexander Hvatov

Large Language Models (LLMs) encounter challenges with the unique syntax of specific domains, such as biomolecules. Existing fine-tuning or modality alignment techniques struggle to bridge the domain knowledge gap and understand complex…

Biomolecules · Quantitative Biology 2024-06-28 Jinzhe Liu , Xiangsheng Huang , Zhuo Chen , Yin Fang

We propose a system identification method, Non-Markovian Optimization-based Modeling for Approximate Dynamics with Spatially-homogeneous memory (NOMADS), for identifying linear dynamical systems from a set of multi-dimensional time-series…

Optimization and Control · Mathematics 2026-01-27 Ryoji Anzaki , Kazuhiro Sato

Dynamical systems form the foundation of scientific discovery, traditionally modeled with predefined state variables such as the angle and angular velocity, and differential equations such as the equation of motion for a single pendulum. We…

Systems and Control · Electrical Eng. & Systems 2025-04-25 Kuang Huang , Dong Heon Cho , Boyuan Chen

Quality-Diversity optimization is a new family of optimization algorithms that, instead of searching for a single optimal solution to solving a task, searches for a large collection of solutions that all solve the task in a different way.…

Robotics · Computer Science 2019-05-29 Antoine Cully