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Patient-derived extracellular vesicles (EVs) that contains a complex biological cargo is a valuable source of liquid biopsy diagnostics to aid in early detection, cancer screening, and precision nanotherapeutics. In this study, we predicted…

Two-photon absorption (TPA) fluorescence of biomarkers has been decisive in advancing the fields of biosensing and deep-tissue in vivo imaging of live specimens. However, due to the extremely small TPA cross section and the quadratic…

Optics · Physics 2020-06-25 Tian Li , Fu Li , Charles Altuzarra , Anton Classen , Girish S. Agarwal

Deep-learning (DL)-based methods have shown significant promise in denoising myocardial perfusion SPECT images acquired at low dose. For clinical application of these methods, evaluation on clinical tasks is crucial. Typically, these…

Image and Video Processing · Electrical Eng. & Systems 2023-03-02 Md Ashequr Rahman , Zitong Yu , Barry A. Siegel , Abhinav K. Jha

In this work, we introduce an innovative approach to estimate the vital signs of multiple human subjects simultaneously in a non-contact way using a Frequency Modulated Continuous Wave (FMCW) radar-based system. Traditional vital sign…

Systems and Control · Electrical Eng. & Systems 2025-12-01 Jewel Benny , Narahari N. Moudhgalya , Mujeev Khan , Hemant Kumar Meena , Mohd Wajid , Abhishek Srivastava

In this article we show that the vector-Apodizing Phase Plate (vAPP) coronagraph can be designed such that the coronagraphic point spread functions (PSFs) can act as a wavefront sensor to measure and correct the (quasi-)static aberrations,…

Instrumentation and Methods for Astrophysics · Physics 2019-11-27 Steven P. Bos , David S. Doelman , Julien Lozi , Olivier Guyon , Christoph U. Keller , Kelsey L. Miller , Nemanja Jovanovic , Frantz Martinache , Frans Snik

Purpose: To develop and evaluate an end-to-end deep learning pipeline for segmentation and analysis of cardiac magnetic resonance images to provide core-lab processing for a multi-centre registry of Fontan patients. Materials and Methods:…

Fundus fluorescein angiography (FFA) is critical for diagnosing retinal vascular diseases, but beginners often struggle with image interpretation. This study develops FFA Sora, a text-to-video model that converts FFA reports into dynamic…

Computer Vision and Pattern Recognition · Computer Science 2024-12-24 Xinyuan Wu , Lili Wang , Ruoyu Chen , Bowen Liu , Weiyi Zhang , Xi Yang , Yifan Feng , Mingguang He , Danli Shi

Flow cytometry is a technique that measures multiple fluorescence and light scatter-associated parameters from individual cells as they flow a single file through an excitation light source. These cells are labeled with antibodies to detect…

Myocardial infarction (MI), commonly known as a heart attack, is a critical health condition caused by restricted blood flow to the heart. Early-stage detection through continuous ECG monitoring is essential to minimize irreversible damage.…

Machine Learning · Computer Science 2024-11-28 Abhijith S , Arjun Rajesh , Mansi Manoj , Sandra Davis Kollannur , Sujitta R , Jerrin Thomas Panachakel

In recent years, the use of bio-sensing signals such as electroencephalogram (EEG), electrocardiogram (ECG), etc. have garnered interest towards applications in affective computing. The parallel trend of deep-learning has led to a huge leap…

Machine Learning · Computer Science 2019-05-20 Siddharth Siddharth , Tzyy-Ping Jung , Terrence J. Sejnowski

Protein-based therapeutics play a pivotal role in modern medicine targeting various diseases. Despite their therapeutic importance, these products can aggregate and form subvisible particles (SvPs), which can compromise their efficacy and…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Michaela Cohrs , Shiwoo Koak , Yejin Lee , Yu Jin Sung , Wesley De Neve , Hristo L. Svilenov , Utku Ozbulak

There are various automotive applications that rely on correctly interpreting point cloud data recorded with radar sensors. We present a deep learning approach for histogram-based processing of such point clouds. Compared to existing…

Computer Vision and Pattern Recognition · Computer Science 2023-03-07 Maxim Tatarchenko , Kilian Rambach

This study develops a Convolutional Neural Network (CNN) model for detecting myocardial infarction (MI) from Electrocardiogram (ECG) images. The model, built using the InceptionV3 architecture and optimized through transfer learning, was…

Ventricular Fibrillation (VF), one of the most dangerous arrhythmias, is responsible for sudden cardiac arrests. Thus, various algorithms have been developed to predict VF from Electrocardiogram (ECG), which is a binary classification…

Machine Learning · Computer Science 2019-03-13 Nabil Ibtehaz , M. Saifur Rahman , M. Sohel Rahman

Human health can be critically affected by cardiovascular diseases, such as hypertension, arrhythmias, and stroke. Heart rate and blood pressure are important biometric information for the monitoring of cardiovascular system and early…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Gyutae Hwang , Sang Jun Lee

We train and validate a semi-supervised, multi-task LSTM on 57,675 person-weeks of data from off-the-shelf wearable heart rate sensors, showing high accuracy at detecting multiple medical conditions, including diabetes (0.8451), high…

Localization of chest pathologies in chest X-ray images is a challenging task because of their varying sizes and appearances. We propose a novel weakly supervised method to localize chest pathologies using class aware deep multiscale…

Computer Vision and Pattern Recognition · Computer Science 2018-08-28 Suman Sedai , Dwarikanath Mahapatra , Zongyuan Ge , Rajib Chakravorty , Rahil Garnavi

Pain management and severity detection are crucial for effective treatment, yet traditional self-reporting methods are subjective and may be unsuitable for non-verbal individuals (people with limited speaking skills). To address this…

Computer Vision and Pattern Recognition · Computer Science 2025-02-27 Aafaf Ridouan , Amine Bohi , Youssef Mourchid

Imaging the bio-impedance distribution of the brain can provide initial diagnosis of acute stroke. This paper presents a compact and non-radiative tomographic modality, i.e. multi-frequency Electromagnetic Tomography (mfEMT), for the…

Applied Physics · Physics 2020-07-29 Jinxi Xiang , Yonggui Dong , Yunjie Yang

This paper presents a deep learning-based wound classification tool that can assist medical personnel in non-wound care specialization to classify five key wound conditions, namely deep wound, infected wound, arterial wound, venous wound,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-30 Po-Hsuan Huang , Yi-Hsiang Pan , Ying-Sheng Luo , Yi-Fan Chen , Yu-Cheng Lo , Trista Pei-Chun Chen , Cherng-Kang Perng