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Many disease models focus on characterizing the underlying transmission mechanism but make simple, possibly naive assumptions about how infections are reported. In this note, we use a simple deterministic Susceptible-Infected-Removed (SIR)…
Identifiability is the property in mathematical modelling that determines if model parameters can be uniquely estimated from data. For infectious disease models, failure to ensure identifiability can lead to misleading parameter estimates…
One of the most significant challenges in combating against the spread of infectious diseases was the difficulty in estimating the true magnitude of infections. Unreported infections could drive up disease spread, making it very hard to…
We consider a stochastic Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model with a contact rate that fluctuates seasonally. Through the use of a nonlinear, stochastic projection, we are able to analytically determine the…
In conducting preliminary analysis during an epidemic, data on reported disease cases offer key information in guiding the direction to the in-depth analysis. Models for growth and transmission dynamics are heavily dependent on preliminary…
The integration of empirical data in computational frameworks to model the spread of infectious diseases poses challenges that are becoming pressing with the increasing availability of high-resolution information on human mobility and…
Dynamic properties of spreading infection through a heterogeneous population are studied numerically and analytically using a dynamic variant of Watts and Strogatz Small World Network-based stochastic Susceptible-Exposed-Infectious-Removed…
The spread of infectious diseases crucially depends on the pattern of contacts among individuals. Knowledge of these patterns is thus essential to inform models and computational efforts. Few empirical studies are however available that…
Infectious disease modeling and forecasting have played a key role in helping assess and respond to epidemics and pandemics. Recent work has leveraged data on disease peak infection and peak hospital incidence to fit compartmental models…
We consider in this paper a general SEIRS model describing the dynamics of an infectious disease including latency, waning immunity and infection-induced mortality. We derive an infinite system of differential equations that provides an…
As a consequence of missing data on tests for infection and imperfect accuracy of tests, reported rates of population infection by the SARS CoV-2 virus are lower than actual rates of infection. Hence, reported rates of severe illness…
The ability to actually implement epidemic models is a crucial stake for public institutions, as they may be overtaken by the increasing complexity of current models and sometimes tend to revert to less elaborate models such as the SIR. In…
This paper focuses on and analyzes realistic SIR models that take stochasticity into account. The proposed systems are applicable to most incidence rates that are used in the literature including the bilinear incidence rate, the…
This paper is concerned with a stochastic model for the spread of an SEIR (susceptible -> exposed (=latent) -> infective -> removed) epidemic with a contact tracing scheme, in which removed individuals may name some of their infectious…
Since 1927, until recently, models describing the spread of disease have mostly been of the SIR-compartmental type, based on the assumption that populations are homogeneous and well-mixed. The focus of these models have typically been on…
A plethora of prediction models of SARS-CoV-2 pandemic were proposed in the past. Prediction performances not only depend on the structure and features of the model, but also on its parametrization. Official databases are often biased due…
In this project, identifiability, observability and uncertainty properties of the deterministic and Chain Binomial stochastic SIR, SEIR and SEIAR epidemiological models are studied. Techniques for modeling overdispersion are investigated…
This paper presents a simple continuous-time linear vaccination-based control strategy for a SEIR (susceptible plus infected plus infectious plus removed populations) propagation disease model. The model takes into account the total…
Within the likes of any highly contagious and unpredictable disease, lies a predictable and attainable growth rate that researchers can find in order to make logistical conclusions about that particular disease and its affected regions'…
We consider the problem of identifying an infection source based only on an observed set of infected nodes in a network, assuming that the infection process follows a Susceptible-Infected-Susceptible (SIS) model. We derive an estimator…