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Image synthesis is currently one of the most addressed image processing topic in computer vision and deep learning fields of study. Researchers have tackled this problem focusing their efforts on its several challenging problems, e.g. image…

Machine Learning · Computer Science 2020-06-26 Tomaso Fontanini , Eleonora Iotti , Luca Donati , Andrea Prati

Tissue segmentation is an important pre-requisite for efficient and accurate diagnostics in digital pathology. However, it is well known that whole-slide scanners can fail in detecting all tissue regions, for example due to the tissue type,…

Computer Vision and Pattern Recognition · Computer Science 2017-04-04 Péter Bándi , Rob van de Loo , Milad Intezar , Daan Geijs , Francesco Ciompi , Bram van Ginneken , Jeroen van der Laak , Geert Litjens

Deep networks are now ubiquitous in large-scale multi-center imaging studies. However, the direct aggregation of images across sites is contraindicated for downstream statistical and deep learning-based image analysis due to inconsistent…

Image and Video Processing · Electrical Eng. & Systems 2021-04-16 Mengwei Ren , Neel Dey , James Fishbaugh , Guido Gerig

Performance of deep learning algorithms decreases drastically if the data distributions of the training and testing sets are different. Due to variations in staining protocols, reagent brands, and habits of technicians, color variation in…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Abhijeet Patil , Mohd. Talha , Aniket Bhatia , Nikhil Cherian Kurian , Sammed Mangale , Sunil Patel , Amit Sethi

Domain adaptation (DA) techniques have the potential in machine learning to alleviate distribution differences between training and test sets by leveraging information from source domains. In image classification, most advances in DA have…

Computer Vision and Pattern Recognition · Computer Science 2025-08-29 Ahmad Chaddad , Yihang Wu , Reem Kateb , Christian Desrosiers

X-ray images play a vital role in the intraoperative processes due to their high resolution and fast imaging speed and greatly promote the subsequent segmentation, registration and reconstruction. However, over-dosed X-rays superimpose…

Image and Video Processing · Electrical Eng. & Systems 2024-08-01 Lixing Tan , Shuang Song , Kangneng Zhou , Chengbo Duan , Lanying Wang , Huayang Ren , Linlin Liu , Wei Zhang , Ruoxiu Xiao

The primary motivation of Image-to-Image Transformation is to convert an image of one domain to another domain. Most of the research has been focused on the task of image transformation for a set of pre-defined domains. Very few works are…

Computer Vision and Pattern Recognition · Computer Science 2019-01-14 Kishan Babu Kancharagunta , Shiv Ram Dubey

Assessing the Mitotic Count has a known high degree of intra- and inter-rater variability. Computer-aided systems have proven to decrease this variability and reduce labeling time. These systems, however, are generally highly dependent on…

Image and Video Processing · Electrical Eng. & Systems 2022-03-16 Frauke Wilm , Christian Marzahl , Katharina Breininger , Marc Aubreville

Semantic segmentation under domain shift remains a fundamental challenge in computer vision, particularly when labelled training data is scarce. This challenge is particularly exemplified in histopathology image analysis, where the same…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Zeeshan Nisar , Friedrich Feuerhake , Thomas Lampert

This work addresses how to efficiently classify challenging histopathology images, such as gigapixel whole-slide images for cancer diagnostics with image-level annotation. We use images with annotated tumor regions to identify a set of…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mohammad Iqbal Nouyed , Mary-Anne Hartley , Gianfranco Doretto , Donald A. Adjeroh

Clinical decision support using deep neural networks has become a topic of steadily growing interest. While recent work has repeatedly demonstrated that deep learning offers major advantages for medical image classification over traditional…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Alexander Katzmann , Oliver Taubmann , Stephen Ahmad , Alexander Mühlberg , Michael Sühling , Horst-Michael Groß

Supervised Pix2Pix and unsupervised Cycle-consistency are two modes that dominate the field of medical image-to-image translation. However, neither modes are ideal. The Pix2Pix mode has excellent performance. But it requires paired and well…

Image and Video Processing · Electrical Eng. & Systems 2021-11-12 Lingke Kong , Chenyu Lian , Detian Huang , Zhenjiang Li , Yanle Hu , Qichao Zhou

Despite the recent success of domain generalization in medical image segmentation, voxel-wise annotation for all source domains remains a huge burden. Semi-supervised domain generalization has been proposed very recently to combat this…

Computer Vision and Pattern Recognition · Computer Science 2024-08-02 Muyang Qiu , Jian Zhang , Lei Qi , Qian Yu , Yinghuan Shi , Yang Gao

Image-to-image translation has gained popularity in the medical field to transform images from one domain to another. Medical image synthesis via domain transformation is advantageous in its ability to augment an image dataset where images…

Image and Video Processing · Electrical Eng. & Systems 2024-01-08 Cassandra Czobit , Reza Samavi

Recognizing atypical mitotic figures in histopathology images allows physicians to correctly assess tumor aggressiveness. Although machine learning models could be exploited for automatically performing such a task, under domain shift these…

Image and Video Processing · Electrical Eng. & Systems 2025-09-10 Gennaro Percannella , Mattia Sarno , Francesco Tortorella , Mario Vento

Domain shift between medical images from multicentres is still an open question for the community, which degrades the generalization performance of deep learning models. Generative adversarial network (GAN), which synthesize plausible…

Image and Video Processing · Electrical Eng. & Systems 2020-07-31 Xinpeng Xie , Jiawei Chen , Yuexiang Li , Linlin Shen , Kai Ma , Yefeng Zheng

Unsupervised image-to-image translation methods such as CycleGAN learn to convert images from one domain to another using unpaired training data sets from different domains. Unfortunately, these approaches still require centrally collected…

Computer Vision and Pattern Recognition · Computer Science 2021-06-18 Joonyoung Song , Jong Chul Ye

Machine learning techniques used in computer-aided medical image analysis usually suffer from the domain shift problem caused by different distributions between source/reference data and target data. As a promising solution, domain…

Computer Vision and Pattern Recognition · Computer Science 2021-10-26 Hao Guan , Mingxia Liu

In this study, a new Anomaly Detection (AD) approach for industrial and medical images is proposed. This method leverages the theoretical strengths of unsupervised learning and the data availability of both normal and abnormal classes.…

Computer Vision and Pattern Recognition · Computer Science 2024-01-24 Arnaud Bougaham , Valentin Delchevalerie , Mohammed El Adoui , Benoît Frénay

Stain variations often decrease the generalization ability of deep learning based approaches in digital histopathology analysis. Two separate proposals, namely stain normalization (SN) and stain augmentation (SA), have been spotlighted to…

Computer Vision and Pattern Recognition · Computer Science 2023-03-03 Yiqing Shen , Yulin Luo , Dinggang Shen , Jing Ke