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Complex, oscillatory data arises from a large variety of biological, physical, and social systems. However, the inherent oscillation and ubiquitous noise pose great challenges to current methodology such as linear and nonlinear time series…

Chaotic Dynamics · Physics 2008-09-19 J. Zhang , K. Zhang , J. Feng , J. Sun , X. Xu , M. Small

Synthetic biology sets out to implement new functions in cells, and to develop a deeper understanding of biological design principles. In 2000, Elowitz and Leibler showed that by rational design of the reaction network, and using existing…

Biological Physics · Physics 2017-05-17 Joris Paijmans , David K Lubensky , Pieter Rein ten Wolde

Genetic oscillators are present in the cells of many organisms and control several biological processes. The common feature of such oscillators is the presence of a protein which represses the transcription of its own gene. Recently, it has…

Molecular Networks · Quantitative Biology 2017-06-07 Nahuel Almeira , Sebastian Risau Gusman

Shared upstream dynamical processes are frequently the source of common inputs in various physical and biological systems. However, due to finite signal transmission speeds and differences in the distance to the source, time shifts between…

Neurons and Cognition · Quantitative Biology 2017-03-10 Ehsan Bolhasani , Yousef Azizi , Alireza Valizadeh , Matjaz Perc

Chemical reactions in cell are subject to intense stochastic fluctuations. An important question is how the fundamental physiological behavior of cell is kept stable against those noisy perturbations. In this paper a stochastic model of…

Molecular Networks · Quantitative Biology 2009-11-13 Yurie Okabe , Masaki Sasai

Gene expression is a biochemical process, where stochastic binding and un-binding events naturally generate fluctuations and cell-to-cell variability in gene dynamics. These fluctuations typically have destructive consequences for proper…

Populations and Evolution · Quantitative Biology 2022-03-22 Yen Ting Lin , Nicolas E. Buchler

Motivation: One of the branches of Systems Biology is focused on a deep understanding of underlying regulatory networks through the analysis of the biomolecules oscillations and their interplay. Synthetic Biology exploits gene or/and…

Molecular Networks · Quantitative Biology 2020-11-30 Francesco Bardozzo , Pietro Liò , Roberto Tagliaferri

Biomedical signals carry signature rhythms of complex physiological processes that control our daily bodily activity. The properties of these rhythms indicate the nature of interaction dynamics among physiological processes that maintain a…

Machine Learning · Computer Science 2020-12-14 Yassin Khalifa , Danilo Mandic , Ervin Sejdić

Circadian rhythms are biological rhythms of approximately 24 h that persist even under constant conditions without environmental daily cues. The molecular circadian clock machinery generates the physiological rhythms, which can be…

Molecular Networks · Quantitative Biology 2022-10-05 Hotaka Kaji , Fumito Mori , Hiroshi Ito

Pancreatic $\beta-$cells regulate insulin secretion through complex oscillations, which are vital for glucose control and diabetes research. In this paper, an existing mathematical model of $\beta-$cell dynamics is analyzed using a…

Dynamical Systems · Mathematics 2025-05-27 Navojit Dhali Pallab

We examine microscopic mechanisms for coupling stochastic oscillators so that they display similar and correlated temporal variations. Unlike oscillatory motion in deterministic dynamical systems, complete synchronization of stochastic…

Quantitative Methods · Quantitative Biology 2009-09-29 Amitabha Nandi , G. Santhosh , R. K. Brojen Singh , Ram Ramaswamy

Robust oscillations play crucial roles in a wide variety of biological processes and are often generated by deterministic mechanisms. However, stochastic fluctuations often generate complex perturbations of these deterministic oscillations,…

Dynamical Systems · Mathematics 2026-03-27 Xuesong Bai , Jonathan Touboul , Thomas G. Fai

If an oscillator is driven by a force that switches between two frequencies, the dynamics it exhibits depends on the precise manner of switching. Here we take a one-dimensional oscillator and consider scenarios in which switching occurs:…

Dynamical Systems · Mathematics 2021-07-28 Carles Bonet , Mike R. Jeffreyy , Pau Martin , Josep M. Olm

The response of lipid bilayers to osmotic stress is an important part of cellular function. Previously, in [Oglecka et al. 2014], we reported that cell-sized giant unilamellar vesicles (GUVs) exposed to hypotonic media, respond to the…

Biological Physics · Physics 2017-05-03 Morgan Chabanon , James C. S. Ho , Bo Liedberg , Atul N. Parikh , Padmini Rangamani

Oscillations are a powerful tool for building examples of colorings witnessing negative partition relations. We survey several results illustrating the general technique and present a number of applications.

Logic · Mathematics 2011-10-05 Laura Fontanella , Boban Velickovic

Oscillations and noise are ubiquitous in physical and biological systems. When oscillations arise from a deterministic limit cycle, entrainment and synchronization may be analyzed in terms of the asymptotic phase function. In the presence…

Neurons and Cognition · Quantitative Biology 2015-01-20 Peter J. Thomas , Benjamin Lindner

Oscillatory systems arise in the different science fields. Complex mathematical formulations with differential equations have been proposed to model the dynamics of these systems. While they have the advantage of having a direct…

Neurons and Cognition · Quantitative Biology 2022-05-02 Cristina Rueda , Alejandro Rodríguez-Collado , Yolanda Larriba

Non-equilibrium processes which convert chemical energy into mechanical motion enable the motility of organisms. Bundles of inextensible filaments driven by energy transduction of molecular motors form essential components of micron-scale…

Soft Condensed Matter · Physics 2013-06-13 Abhrajit Laskar , Rajeev Singh , Somdeb Ghose , Gayathri Jayaraman , P. B. Sunil Kumar , R. Adhikari

Oscillations lie at the core of many biological processes, from the cell cycle, to circadian oscillations and developmental processes. Time-keeping mechanisms are essential to enable organisms to adapt to varying conditions in environmental…

Machine Learning · Statistics 2015-04-27 D Trejo , AJ Millar , G Sanguinetti

We demonstrate that entanglement can persistently recur in an oscillating two-spin molecule that is coupled to a hot and noisy environment, in which no static entanglement can survive. The system represents a non-equilibrium quantum system…

Quantum Physics · Physics 2014-02-28 Jianming Cai , Sandu Popescu , Hans J. Briegel