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Deep learning-based super-resolution (SR) techniques have generally achieved excellent performance in the computer vision field. Recently, it has been proven that three-dimensional (3D) SR for medical volumetric data delivers better visual…

In inertial confinement fusion (ICF), X-ray radiography is a critical diagnostic for measuring implosion dynamics, which contains rich 3D information. Traditional methods for reconstructing 3D volumes from 2D radiographs, such as filtered…

Reconstruction of PET images is an ill-posed inverse problem and often requires iterative algorithms to achieve good image quality for reliable clinical use in practice, at huge computational costs. In this paper, we consider the PET…

Achieving high-quality Magnetic Resonance Imaging (MRI) reconstruction at accelerated acquisition rates remains challenging due to the inherent ill-posed nature of the inverse problem. Traditional Compressed Sensing (CS) methods, while…

Magnetic Resonance Imaging (MRI) is a technology for non-invasive imaging of anatomical features in detail. It can help in functional analysis of organs of a specimen but it is very costly. In this work, methods for (i) virtual…

High-dimensional hyperspectral imaging (HSI) enables the visualization of ultrafast molecular dynamics and complex, heterogeneous spectra. However, applying this capability to resolve spatially varying vibrational couplings in…

With the thriving of deep learning, 3D Convolutional Neural Networks have become a popular choice in volumetric image analysis due to their impressive 3D contexts mining ability. However, the 3D convolutional kernels will introduce a…

Magnetic Resonance Imaging (MRI) is a noninvasive imaging technique that provides exquisite soft-tissue contrast without using ionizing radiation. The clinical application of MRI may be limited by long data acquisition times; therefore, MR…

Segmentation of 3D images is a fundamental problem in biomedical image analysis. Deep learning (DL) approaches have achieved state-of-the-art segmentation perfor- mance. To exploit the 3D contexts using neural networks, known DL…

Medical image segmentation plays a vital role in various clinical applications, enabling accurate delineation and analysis of anatomical structures or pathological regions. Traditional CNNs have achieved remarkable success in this field.…

Unrolled neural networks have recently achieved state-of-the-art accelerated MRI reconstruction. These networks unroll iterative optimization algorithms by alternating between physics-based consistency and neural-network based…

Convolutional Neural Networks (CNN) have emerged as powerful tools for learning discriminative image features. In this paper, we propose a framework of 3-D fully CNN models for Glioblastoma segmentation from multi-modality MRI data. By…

Prostate gland segmentation from T2-weighted MRI is a critical yet challenging task in clinical prostate cancer assessment. While deep learning-based methods have significantly advanced automated segmentation, most conventional…

Magnetic resonance imaging (MRI) using hyperpolarized noble gases provides a way to visualize the structure and function of human lung, but the long imaging time limits its broad research and clinical applications. Deep learning has…

Deep Learning (DL) methods can reconstruct highly accelerated magnetic resonance imaging (MRI) scans, but they rely on application-specific large training datasets and often generalize poorly to out-of-distribution data. Self-supervised…

Large kernel convolutions offer a scalable alternative to vision transformers for high-resolution 3D volumetric analysis, yet naively increasing kernel size often leads to optimization instability. Motivated by the spatial bias inherent in…

Computational imaging systems jointly design computation and hardware to retrieve information which is not traditionally accessible with standard imaging systems. Recently, critical aspects such as experimental design and image priors are…

Computed tomography (CT) is increasingly being used for cancer screening, such as early detection of lung cancer. However, CT studies have varying pixel spacing due to differences in acquisition parameters. Thick slice CTs have lower…

We introduce a model-based image reconstruction framework with a convolution neural network (CNN) based regularization prior. The proposed formulation provides a systematic approach for deriving deep architectures for inverse problems with…

Radiation therapy (RT) is widely employed in the clinic for the treatment of head and neck (HaN) cancers. An essential step of RT planning is the accurate segmentation of various organs-at-risks (OARs) in HaN CT images. Nevertheless,…