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Epidemiological models may give some basic guidelines for public health practitioners, allowing to analyze issues that can influence the strategies to prevent and fight a disease. To be used in decision-making, however, a mathematical model…

Populations and Evolution · Quantitative Biology 2013-08-15 Helena Sofia Rodrigues , M. Teresa T. Monteiro , Delfim F. M. Torres

The emergence of novel infectious agents presents challenges to statistical models of disease transmission. These challenges arise from limited, poor-quality data and an incomplete understanding of the agent. Moreover, outbreaks manifest…

Methodology · Statistics 2024-03-20 Jiasheng Shi , Jeffrey S. Morris , David M. Rubin , Jing Huang

Incidence vs Cumulative Cases (ICC) curves are introduced and shown to provide a simple framework for parameter identification in the case of the most elementary epidemiological model, consisting of susceptible, infected, and removed…

Populations and Evolution · Quantitative Biology 2021-04-14 Joceline Lega

A prompt public health response to a new epidemic relies on the ability to monitor and predict its evolution in real time as data accumulate. The 2009 A/H1N1 outbreak in the UK revealed pandemic data as noisy, contaminated, potentially…

Effective containment of spreading processes such as epidemics requires accurate knowledge of several key parameters that govern their dynamics. In this work, we first show that the problem of identifying the underlying parameters of…

Systems and Control · Electrical Eng. & Systems 2023-11-03 Chi Ho Leung , William E. Retnaraj , Ashish R. Hota , Philip E. Paré

Much traditional statistical modelling assumes that the outcome variables of interest are independent of each other when conditioned on the explanatory variables. This assumption is strongly violated in the case of infectious diseases,…

Populations and Evolution · Quantitative Biology 2019-11-28 Timothy Kinyanjui , Thomas House

Background: Over the past few decades, numerous forecasting methods have been proposed in the field of epidemic forecasting. Such methods can be classified into different categories such as deterministic vs. probabilistic, comparative…

Social media services such as Twitter are a valuable source of information for decision support systems. Many studies have shown that this also holds for the medical domain, where Twitter is considered a viable tool for public health…

A key parameter in models for the spread of infectious diseases is the basic reproduction number $R_0$, which is the expected number of secondary cases a typical infected primary case infects during its infectious period in a large mostly…

Populations and Evolution · Quantitative Biology 2017-09-05 Kristoffer Spricer , Pieter Trapman

Compartmental epidemic models have been widely used for predicting the course of epidemics, from estimating the basic reproduction number to guiding intervention policies. Studies commonly acknowledge these models' assumptions but less…

Populations and Evolution · Quantitative Biology 2022-11-23 Alexander F. Siegenfeld , Pratyush K. Kollepara , Yaneer Bar-Yam

Many epidemic models are naturally defined as individual-based models: where we track the state of each individual within a susceptible population. Inference for individual-based models is challenging due to the high-dimensional state-space…

Methodology · Statistics 2025-08-04 Lorenzo Rimella , Christopher Jewell , Paul Fearnhead

The paper presents an algorithm for syndromic surveillance of an epidemic outbreak formulated in the context of stochastic nonlinear filtering. The dynamics of the epidemic is modeled using a generalized compartmental epidemiological model…

Quantitative Methods · Quantitative Biology 2011-10-24 Alex Skvortsov , Branko Ristic

Epidemic forecasting has become an integral part of real-time infectious disease outbreak response. While collaborative ensembles composed of statistical and machine learning models have become the norm for real-time forecasting,…

Epidemiological models describe the spread of an infectious disease within a population. They capture microscopic details on how the disease is passed on among individuals in various different ways, while making predictions about the state…

Populations and Evolution · Quantitative Biology 2024-02-27 Stefan Hohenegger , Francesco Sannino

The rapidly spreading Covid-19 that affected almost all countries, was first reported at the end of 2019. As a consequence of its highly infectious nature, countries all over the world have imposed extremely strict measures to control its…

Populations and Evolution · Quantitative Biology 2020-07-13 Semra Ahmetolan , Ayse Humeyra Bilge , Ali Demirci , Ayse Peker-Dobie , Onder Ergonul

Obtaining accurate forecasts for the evolution of epidemic outbreaks from deterministic compartmental models represents a major theoretical challenge. Recently, it has been shown that these models typically exhibit trajectories' degeneracy,…

The fundamental models of epidemiology describe the progression of an infectious disease through a population using compartmentalized differential equations, but do not incorporate population-level heterogeneity in infection susceptibility.…

Populations and Evolution · Quantitative Biology 2023-08-04 Christopher Rose , Andrew J. Medford , C. Franklin Goldsmith , Tejs Vegge , Joshua S. Weitz , Andrew A. Peterson

Studies about epidemic modelling have been conducted since before 19th century. Both deterministic and stochastiic model were used to capture the dynamic of infection in the population. The purpose of this project is to investigate the…

Populations and Evolution · Quantitative Biology 2018-03-06 Kurnia Susvitasari

Containment of epidemic outbreaks entails great societal and economic costs. Cost-effective containment strategies rely on efficiently identifying infected individuals, making the best possible use of the available testing resources.…

Populations and Evolution · Quantitative Biology 2020-12-01 Laura Natali , Saga Helgadottir , Onofrio M. Marago , Giovanni Volpe

The massive employment of computational models in network epidemiology calls for the development of improved inference methods for epidemic forecast. For simple compartment models, such as the Susceptible-Infected-Recovered model, Belief…

Physics and Society · Physics 2017-07-05 Jacopo Bindi , Alfredo Braunstein , Luca Dall'Asta
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