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Non-pharmaceutical interventions (NPIs) are crucial for controlling pandemics, but existing research often overlooks the heterogeneity of individual behavior, which can lead to inaccurate evaluations of the effectiveness of strategies. In…

Physics and Society · Physics 2026-03-09 Xihan Zhang , Yuqing Liu , Chen Zhao , Guijun Li

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

Applications · Statistics 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

We present a phenomenological procedure of dealing with the COVID--19 data provided by government health agencies of eleven different countries. Instead of using the (exact or approximate) solutions to the SIR (or other) model(s) to fit the…

Physics and Society · Physics 2020-12-02 Sergio A. Hojman , Felipe A. Asenjo

We study how international flights can facilitate the spread of an epidemic to a worldwide scale. We combine an infrastructure network of flight connections with a population density dataset to derive the mobility network, and then we…

Physics and Society · Physics 2021-07-26 Hugo Dolan , Riccardo Rastelli

The COVID-19 pandemic has emphasized the need for a robust understanding of epidemic models. Current models of epidemics are classified as either mechanistic or non-mechanistic: mechanistic models make explicit assumptions on the dynamics…

Machine Learning · Statistics 2022-01-14 Arnab Sarker , Ali Jadbabaie , Devavrat Shah

Infectious diseases and human behavior are intertwined. On one side, our movements and interactions are the engines of transmission. On the other, the unfolding of viruses might induce changes to our daily activities. While intuitive, our…

Physics and Society · Physics 2021-06-02 Nicola Perra

Mathematical modelling is a widely used approach to understand and interpret clinical trial data. This modelling typically involves fitting mechanistic mathematical models to data from individual trial participants. Despite the widespread…

COVID-19 pandemic has sharply projected the globally persistent multi-dimensional fundamental challenges in securing general socio-economic wellbeing of the society. The problems intensify with increasing population densities and also vary…

Computers and Society · Computer Science 2021-05-25 Pradipta Banerjee , Subhrabrata Choudhury

Non-pharmaceutical interventions (NPIs), including mask-wearing, physical distancing, and hygiene measures, provide the primary means of reducing transmission in the early stages of an epidemic. Individuals adopt one of two…

Populations and Evolution · Quantitative Biology 2026-05-22 Yuan Liu , Michael Sieber , Bin Wu , Arne Traulsen

In response to the COVID-19 pandemic and the potential threat of future epidemics caused by novel viruses, we developed a flexible framework for modeling disease intervention effects. This tool is intended to aid decision makers at multiple…

Multiagent Systems · Computer Science 2023-08-22 Karleigh Pine , Razvan Veliche , Jared Bennett , Joel Klipfel

Epidemic models play a key role in understanding and responding to the emerging COVID-19 pandemic. Widely used compartmental models are static and are of limited use to evaluate intervention strategies with the emerging pandemic. Applying…

Populations and Evolution · Quantitative Biology 2021-01-01 Shuo Wang , Xian Yang , Ling Li , Philip Nadler , Rossella Arcucci , Yuan Huang , Zhongzhao Teng , Yike Guo

A crucial aspect of managing a public health crisis is to effectively balance prevention and mitigation strategies, while taking their socio-economic impact into account. In particular, determining the influence of different…

Facing a global epidemic of new infectious diseases such as COVID-19, non-pharmaceutical interventions (NPIs), which reduce transmission rates without medical actions, are being implemented around the world to mitigate spreads. One of the…

Populations and Evolution · Quantitative Biology 2021-03-04 Naoya Fujiwara , Tomokatsu Onaga , Takayuki Wada , Shouhei Takeuchi , Junji Seto , Tomoki Nakaya , Kazuyuki Aihara

Spatiotemporal modelling of infectious diseases such as COVID-19 involves using a variety of epidemiological metrics such as regional proportion of cases or regional positivity rates. Although observing their changes over time is critical…

In an emerging pandemic, policymakers need to make important decisions with limited information, for example choosing between a mitigation, suppression or elimination strategy. These strategies may require trade-offs to be made between the…

Populations and Evolution · Quantitative Biology 2026-05-27 M J Plank , M Sushames , T Fisher-Taylor , A Afshari , R N Thompson , A Hurford , S C Hendy

A model-based signal processing framework is proposed for pandemic trend forecasting and control, by using non-pharmaceutical interventions (NPI) at regional and country levels worldwide. The control objective is to prescribe quantifiable…

Optimization and Control · Mathematics 2021-11-23 Reza Sameni

To date, the only effective means to respond to the spreading of COVID-19 pandemic are non-pharmaceutical interventions (NPIs), which entail policies to reduce social activity and mobility restrictions. Quantifying their effect is…

Physics and Society · Physics 2021-03-01 Francesco Parino , Lorenzo Zino , Maurizio Porfiri , Alessandro Rizzo

To curb the initial spread of SARS-CoV-2, many countries relied on nation-wide implementation of non-pharmaceutical intervention measures, resulting in substantial socio-economic impacts. Potentially, subnational implementations might have…

Physics and Society · Physics 2023-12-19 Mark M. Dekker , Luc E. Coffeng , Frank P. Pijpers , Debabrata Panja , Sake J. de Vlas

Some basic facts that enable or constrain efforts to "flatten the curve" by non-pharmaceutical interventions (NPI) are summarized and placed in the current context of the COVID-19 epidemic. Analytical formulas are presented for a simple…

Populations and Evolution · Quantitative Biology 2020-04-14 Michael Nikolaou

We propose a general Bayesian approach to modeling epidemics such as COVID-19. The approach grew out of specific analyses conducted during the pandemic, in particular an analysis concerning the effects of non-pharmaceutical interventions…

Applications · Statistics 2021-01-01 Samir Bhatt , Neil Ferguson , Seth Flaxman , Axel Gandy , Swapnil Mishra , James A. Scott