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Optoacoustic tomography (OAT), also known as photoacoustic tomography, is a rapidly emerging hybrid imaging technique that possesses great potential for a wide range of biomedical imaging applications. In OAT, a laser is employed to…

Medical Physics · Physics 2016-12-21 Yang Lou , Kun Wang , Alexander. A. Oraevsky , Mark. A. Anastasio

Image reconstruction in photoacoustic tomography relies on an accurate knowledge of the speed of sound in the target. However, the speed of sound distribution is not generally known, which may result in artefacts in the reconstructed…

Medical Physics · Physics 2025-11-06 Miika Suhonen , Felix Lucka , Aki Pulkkinen , Simon Arridge , Ben Cox , Tanja Tarvainen

Fluorescence photoacoustic tomography (fPAT) is a molecular imaging modality that combines photoacoustic tomography (PAT) with fluorescence imaging to obtain high-resolution imaging of fluorescence distributions inside heterogeneous media.…

Analysis of PDEs · Mathematics 2019-09-27 Kui Ren , Rongting Zhang , Yimin Zhong

Inverse problems describe the task of recovering an underlying signal of interest given observables. Typically, the observables are related via some non-linear forward model applied to the underlying unknown signal. Inverting the non-linear…

Signal Processing · Electrical Eng. & Systems 2023-05-19 Jihui Jin , Etienne Ollivier , Richard Touret , Matthew McKinley , Karim G. Sabra , Justin K. Romberg

Biomedical photoacoustic tomography, which can provide high resolution 3D soft tissue images based on the optical absorption, has advanced to the stage at which translation from the laboratory to clinical settings is becoming possible. The…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Andreas Hauptmann , Ben Cox

We consider ill-posed inverse problems where the forward operator $T$ is unknown, and instead we have access to training data consisting of functions $f_i$ and their noisy images $Tf_i$. This is a practically relevant and challenging…

Machine Learning · Statistics 2023-02-21 Miguel del Alamo

Learning good representations without supervision is still an open issue in machine learning, and is particularly challenging for speech signals, which are often characterized by long sequences with a complex hierarchical structure. Some…

Machine Learning · Computer Science 2019-04-09 Santiago Pascual , Mirco Ravanelli , Joan Serrà , Antonio Bonafonte , Yoshua Bengio

Self-supervised methods have emerged as a promising avenue for representation learning in the recent years since they alleviate the need for labeled datasets, which are scarce and expensive to acquire. Contrastive methods are a popular…

Sound · Computer Science 2022-09-07 Elio Quinton

Quantitative photoacoustic tomography is an emerging imaging technique aimed at estimating the distribution of optical parameters inside tissues from photoacoustic images, which are formed by combining optical information and ultrasonic…

Numerical Analysis · Mathematics 2016-06-02 Antti Hannukainen , Nuutti Hyvönen , Helle Majander , Tanja Tarvainen

We consider an undetermined coefficient inverse problem for a nonlinear partial differential equation describing high intensity ultrasound propagation as widely used in medical imaging and therapy. The usual nonlinear term in the standard…

Numerical Analysis · Mathematics 2022-04-13 Barbara Kaltenbacher , William Rundell

Existing approaches to image reconstruction in photoacoustic computed tomography (PACT) with acoustically heterogeneous media are limited to weakly varying media, are computationally burdensome, and/or cannot effectively mitigate the…

Medical Physics · Physics 2013-03-25 Chao Huang , Kun Wang , Liming Nie , Lihong V. Wang , Mark A. Anastasio

The standard approach for photoacoustic imaging with variable speed of sound is time reversal, which consists in solving a well-posed final-boundary value problem for the wave equation backwards in time. This paper investigates the…

Optimization and Control · Mathematics 2016-03-17 Zakaria Belhachmi , Thomas Glatz , Otmar Scherzer

We study iterative signal reconstruction in computed tomography (CT), wherein measurements are produced by a linear transformation of the unknown signal followed by an exponential nonlinear map. Approaches based on pre-processing the data…

Optimization and Control · Mathematics 2024-07-19 Vasileios Charisopoulos , Rebecca Willett

Unsupervised learning is the most challenging problem in machine learning and especially in deep learning. Among many scenarios, we study an unsupervised learning problem of high economic value --- learning to predict without costly pairing…

Machine Learning · Computer Science 2016-06-16 Jianshu Chen , Po-Sen Huang , Xiaodong He , Jianfeng Gao , Li Deng

Multispectral photoacoustic imaging (PAI) is an emerging imaging modality which enables the recovery of functional tissue parameters such as blood oxygenation. However, the underlying inverse problems are potentially ill-posed, meaning that…

Intrinsic image decomposition, which is an essential task in computer vision, aims to infer the reflectance and shading of the scene. It is challenging since it needs to separate one image into two components. To tackle this, conventional…

Computer Vision and Pattern Recognition · Computer Science 2020-05-28 Yunfei Liu , Yu Li , Shaodi You , Feng Lu

We propose a novel learning-based approach for robust 3D shape matching. Our method builds upon deep functional maps and can be trained in a fully unsupervised manner. Previous deep functional map methods mainly focus on predicting…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Dongliang Cao , Paul Roetzer , Florian Bernard

In this article we study the inverse problem of thermoacoustic tomography (TAT) on a medium with attenuation represented by a time- convolution (or memory) term, and whose consideration is motivated by the modeling of ultrasound waves in…

Analysis of PDEs · Mathematics 2017-03-29 Sebastian Acosta , Benjamin Palacios

We propose self-diffusion, a novel framework for solving inverse problems without relying on pretrained generative models. Traditional diffusion-based approaches require training a model on a clean dataset to learn to reverse the forward…

Machine Learning · Computer Science 2025-12-09 Guanxiong Luo , Shoujin Huang , Yanlong Yang

Inverse problems in image reconstruction are fundamentally complicated by unknown noise properties. Classical iterative deconvolution approaches amplify noise and require careful parameter selection for an optimal trade-off between…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Mikhail Papkov , Kaupo Palo , Leopold Parts