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The method of filtered back projection (FBP) is a widely used reconstruction technique in X-ray computerized tomography (CT), which is particularly important in clinical diagnostics. To reduce scanning times and radiation doses in medical…

Numerical Analysis · Mathematics 2024-08-14 Matthias Beckmann , Judith Nickel

We propose a 3D neural network with specific loss functions for quantitative computed tomography (QCT) noise reduction to compute micro-structural parameters such as tissue mineral density (TMD) and bone volume ratio (BV/TV) with…

Image and Video Processing · Electrical Eng. & Systems 2020-11-11 Felix Thomsen , José M. Fuertes García , Manuel Lucena , Juan Pisula , Rodrigo de Luis García , Jan Broggrefe , Claudio Delrieux

While model-based reconstruction methods have been successfully applied to flat-panel cone-beam CT (FP-CBCT) systems, typical implementations ignore both spatial correlations in the projection data as well as system blurs due to the…

Medical Physics · Physics 2017-06-20 Steven Tilley , Jeffrey H. Siewerdsen , J. Webster Stayman

Medical image retrieval refers to the task of finding similar images for given query images in a database, with applications such as diagnosis support. While traditional medical image retrieval relied on clinical metadata, content-based…

Computer Vision and Pattern Recognition · Computer Science 2025-03-28 Amirreza Mahbod , Nematollah Saeidi , Sepideh Hatamikia , Ramona Woitek

For conventional computed tomography (CT) image reconstruction tasks, the most popular method is the so-called filtered-back-projection (FBP) algorithm. In it, the acquired Radon projections are usually filtered first by a ramp kernel…

Medical Physics · Physics 2018-07-06 Yongshuai Ge , Qiyang Zhang , Zhanli Hu , Jianwei Chen , Wei Shi , Hairong Zheng , Dong Liang

Simulation-based image quality metrics are adapted and investigated for characterizing the parameter dependences of linear iterative image reconstruction for DBT. Three metrics based on 2D DBT simulation are investigated: (1) a…

Medical Physics · Physics 2017-11-01 Sean D. Rose , Adrian A. Sanchez , Emil Y. Sidky , Xiaochuan Pan

A variety of deep neural network (DNN)-based image denoising methods have been proposed for use with medical images. These methods are typically trained by minimizing loss functions that quantify a distance between the denoised image, or a…

Image and Video Processing · Electrical Eng. & Systems 2022-11-28 Kaiyan Li , Hua Li , Mark A. Anastasio

Four-dimensional (4D) wide coverage computed tomography (CT) is an effective imaging modality for measuring the mechanical function of the myocardium. However, repeated CT measurement across several heartbeats is still a concern. A…

Medical Physics · Physics 2024-03-14 Zhye Yin , Pengwei Wu , Ashish Manohar , Elliot R. McVeigh , Jed D. Pack

Breast CT provides image volumes with isotropic resolution in high contrast, enabling detection of small calcification (down to a few hundred microns in size) and subtle density differences. Since breast is sensitive to x-ray radiation,…

Image and Video Processing · Electrical Eng. & Systems 2020-11-05 Huidong Xie , Hongming Shan , Wenxiang Cong , Chi Liu , Xiaohua Zhang , Shaohua Liu , Ruola Ning , Ge Wang

Recently, an ultra-low-cost linear scan based tomography architecture was proposed by our team. Similar to linear tomosynthesis, the source and detector are translated in opposite directions and the data acquisition system targets on a…

Medical Physics · Physics 2016-10-21 Weiwen Wu , Hengyong Yu , Shaoyu Wang , Fenglin Liu

Image denoising is a fundamental challenge in computer vision, with applications in photography and medical imaging. While deep learning-based methods have shown remarkable success, their reliance on specific noise distributions limits…

Computer Vision and Pattern Recognition · Computer Science 2025-08-28 Dongjin Kim , Jaekyun Ko , Muhammad Kashif Ali , Tae Hyun Kim

Ultra-low-dose CT (ULDCT) imaging can greatly reduce patient radiation exposure, but the resulting scans suffer from severe structured and random noise that degrades image quality. To address this challenge, we propose a novel Plug-and-Play…

Image and Video Processing · Electrical Eng. & Systems 2026-01-05 Sayantan Dutta , Sudhanya Chatterjee , Ashwini Galande , K. S. Shriram , Bipul Das

Mild Traumatic Brain Injury (mTBI) is a common and challenging condition to diagnose accurately. Timely and precise diagnosis is essential for effective treatment and improved patient outcomes. Traditional diagnostic methods for mTBI often…

Image and Video Processing · Electrical Eng. & Systems 2024-04-09 Hanem Ellethy , Shekhar S. Chandra , Viktor Vegh

In this work, we perform direct material reconstruction from spectral CT data using a model based iterative reconstruction (MBIR) approach. Material concentrations are measured in volume fractions, whose total is constrained by a maximum of…

Image and Video Processing · Electrical Eng. & Systems 2023-09-29 Obaidullah Rahman , Ken Sauer , Connor Evans , Ryan Roeder

Digital breast tomosynthesis (DBT) is an emerging modality for breast imaging. A typical tomosynthesis image is reconstructed from projection data acquired at a limited number of views over a limited angular range. In general, the…

Medical Physics · Physics 2009-08-19 I. Reiser , J. Bian , R. M. Nishikawa , E. Y. Sidky , X. Pan

As Deep Convolutional Neural Networks (DCNNs) have shown robust performance and results in medical image analysis, a number of deep-learning-based tumor detection methods were developed in recent years. Nowadays, the automatic detection of…

Computer Vision and Pattern Recognition · Computer Science 2020-02-12 Zhengdong Zhang , Shuai Li , Ziyang Wang , Yun Lu

In this study we investigated the repeatability and reproducibility of radiomic features extracted from MRI images and provide a workflow to identify robust features. 2D and 3D T$_2$-weighted images of a pelvic phantom were acquired on…

Lowering radiation dose per view and utilizing sparse views per scan are two common CT scan modes, albeit often leading to distorted images characterized by noise and streak artifacts. Blind image quality assessment (BIQA) strives to…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Yongyi Shi , Wenjun Xia , Ge Wang , Xuanqin Mou

A CT image can be well reconstructed when the sampling rate of the sinogram satisfies the Nyquist criteria and the sampled signal is noise-free. However, in practice, the sinogram is usually contaminated by noise, which degrades the quality…

Image and Video Processing · Electrical Eng. & Systems 2020-01-22 Wei Wang , Xiang-Gen Xia , Chuanjiang He , Zemin Ren , Jian Lu , Tianfu Wang , Baiying Lei

High radiation dose in computed tomography (CT) scans increases the lifetime risk of cancer, which become a major clinical concern. The backprojection-filtration (BPF) algorithm could reduce radiation dose by reconstructing images from…

Medical Physics · Physics 2013-11-20 Yan Bin , Deng Lin , Han Yu , Zhang Feng , Wang Xian Chao , Li Lei