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High-frequency oscillations (HFOs) are a new biomarker for identifying the epileptogenic zone. Mapping HFO-generating regions can improve the precision of resection sites in patients with refractory epilepsy. However, detecting HFOs remains…

Computer Vision and Pattern Recognition · Computer Science 2025-10-13 Mostafa Mohammadpour , Mehdi Zekriyapanah Gashti , Yusif S. Gasimov

Over the past decade, high-frequency oscillations (HFOs) have been studied as a promising biomarker for localizing epileptogenic areas in drug-resistant patients requiring pre-surgical intervention, while exploiting intracranial…

Signal Processing · Electrical Eng. & Systems 2024-12-24 Zayneb Sadek , Abir Hadriche , Rahma Maalej , Nawel Jmail

High frequency oscillations (HFOs) are a promising biomarker of epileptic brain tissue and activity. HFOs additionally serve as a prototypical example of challenges in the analysis of discrete events in high-temporal resolution,…

Neurons and Cognition · Quantitative Biology 2017-06-13 Stephen V. Gliske , Kevin R. Moon , William C. Stacey , Alfred O. Hero

In this work, we present a neuromorphic system that combines for the first time a neural recording headstage with a signal-to-spike conversion circuit and a multi-core spiking neural network (SNN) architecture on the same die for recording,…

Signal Processing · Electrical Eng. & Systems 2021-06-09 Mohammadali Sharifshazileh , Karla Burelo , Johannes Sarnthein , Giacomo Indiveri

To achieve seizure freedom, epilepsy surgery requires the complete resection of the epileptogenic brain tissue. In intraoperative ECoG recordings, high frequency oscillations (HFOs) generated by epileptogenic tissue can be used to tailor…

Signal Processing · Electrical Eng. & Systems 2021-08-24 Karla Burelo , Mohammadali Sharifshazileh , Niklaus Krayenbühl , Georgia Ramantani , Giacomo Indiveri , Johannes Sarnthein

Electrophysiological observation plays a major role in epilepsy evaluation. However, human interpretation of brain signals is subjective and prone to misdiagnosis. Automating this process, especially seizure detection relying on scalp-based…

Machine Learning · Computer Science 2018-07-06 David Ahmedt-Aristizabal , Clinton Fookes , Kien Nguyen , Sridha Sridharan

High Frequency Oscillations (HFOs), rapid bursts of brain activity above 80 Hz, have emerged as a highly specific biomarker for epileptogenic tissue. Recent evidence suggests that HFOs are also present in Alzheimer's Disease (AD),…

Signal Processing · Electrical Eng. & Systems 2026-01-13 Samin Yaser , Mahad Ali , Yang Jiang , Phuc Nguyen , Jing Xiang , Laura J. Brattain

High-frequency oscillations (HFOs) in intracranial Electroencephalography (iEEG) are critical biomarkers for localizing the epileptogenic zone in epilepsy treatment. However, traditional rule-based detectors for HFOs suffer from…

Computational Engineering, Finance, and Science · Computer Science 2025-07-22 Yipeng Zhang , Yuanyi Ding , Chenda Duan , Atsuro Daida , Hiroki Nariai , Vwani Roychowdhury

Objective: The surgical resection of brain areas with high rates of visually identified high frequency oscillations (HFOs) on EEG has been correlated with improved seizure control. However, it can be difficult to distinguish normal from…

Neurons and Cognition · Quantitative Biology 2013-09-05 David Hsu , Murielle Hsu , Heidi L. Grabenstatter , Gregory A. Worrell , Thomas P. Sutula

Epilepsy is the fourth most common neurological disorder, affecting about 1% of the population at all ages. As many as 60% of people with epilepsy experience focal seizures which originate in a certain brain area and are limited to part of…

Machine Learning · Computer Science 2019-03-20 Diyuan Lu , Jochen Triesch

We develop a framework to uncover and analyze dynamical anomalies from massive, nonlinear and non-stationary time series data. The framework consists of three steps: preprocessing of massive data sets to eliminate erroneous data segments,…

Medical Physics · Physics 2016-12-26 Liang Huang , Xuan Ni , William L. Ditto , Mark Spano , Paul R. Carney , Ying-Cheng Lai

Epilepsy is a neurological disorder and for its detection, encephalography (EEG) is a commonly used clinical approach. Manual inspection of EEG brain signals is a time-consuming and laborious process, which puts heavy burden on neurologists…

Computer Vision and Pattern Recognition · Computer Science 2018-01-17 Ihsan Ullah , Muhammad Hussain , Emad-ul-Haq Qazi , Hatim Aboalsamh

Epilepsy is a highly prevalent brain condition with many serious complications arising from it. The majority of patients which present to a clinic and undergo electroencephalogram (EEG) monitoring would be unlikely to experience seizures…

Signal Processing · Electrical Eng. & Systems 2023-12-14 Matthew McDougall , Hezam Albaqami , Ghulam Mubashar Hassan , Amitava Datta

Epileptic seizures are neurological disorders characterized by abnormal and excessive electrical activity in the brain, resulting in recurrent seizure events. Electroencephalogram (EEG) signals are widely used for seizure diagnosis due to…

Machine Learning · Computer Science 2026-04-02 Ferdaus Anam Jibon , Fazlul Hasan Siddiqui , F. Deeba , Gahangir Hossain

Epilepsy, affecting approximately 50 million people globally, is characterized by abnormal brain activity and remains challenging to treat. The diagnosis of epilepsy relies heavily on electroencephalogram (EEG) data, where specialists…

Epilepsy is one of the most common neurological disorders. This disease requires reliable and efficient seizure detection methods. Electroencephalography (EEG) is the gold standard for seizure monitoring, but its manual analysis is a…

Signal Processing · Electrical Eng. & Systems 2025-12-17 Annika Stiehl , Nicolas Weeger , Christian Uhl , Dominic Bechtold , Nicole Ille , Stefan Geißelsöder

Electroencephalography (EEG) is a complex signal and can require several years of training to be correctly interpreted. Recently, deep learning (DL) has shown great promise in helping make sense of EEG signals due to its capacity to learn…

Machine Learning · Computer Science 2019-01-23 Yannick Roy , Hubert Banville , Isabela Albuquerque , Alexandre Gramfort , Tiago H. Falk , Jocelyn Faubert

Deep learning techniques have revolutionized the field of machine learning and were recently successfully applied to various classification problems in noninvasive electroencephalography (EEG). However, these methods were so far only rarely…

Recent advances in deep learning have had a methodological and practical impact on brain-computer interface research. Among the various deep network architectures, convolutional neural networks have been well suited for…

Signal Processing · Electrical Eng. & Systems 2020-03-06 Wonjun Ko , Eunjin Jeon , Seungwoo Jeong , Heung-Il Suk

In this study, a novel open-source brain-computer interface (BCI) platform was developed to decode scalp electroencephalography (EEG) signals associated with sustained attention. The EEG signal collection was conducted using a wireless…

Signal Processing · Electrical Eng. & Systems 2024-05-08 Maryam Norouzi , Mohammad Zaeri Amirani , Yalda Shahriari , Reza Abiri
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