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Mechanical systems are often characterized only by their response to certain loads known from experiments or simulations. The obtained data can be used for various purposes: system analysis, design of mathematical models, or construction of…

Dynamical Systems · Mathematics 2026-01-05 Yevgeniya Filanova , Igor Pontes Duff , Pawan Goyal , Peter Benner

BACKGROUND Careful evaluation of the risk of stent under-expansions before the intervention will aid treatment planning, including the application of a pre-stent plaque modification strategy. OBJECTIVES It remains challenging to achieve a…

Predictive modeling of blood flow and pressure have numerous applications ranging from non-invasive assessment of functional significance of disease to planning invasive procedures. While several such predictive modeling techniques have…

Simulation of arterial stenting procedures prior to intervention allows for appropriate device selection as well as highlights potential complications. To this end, we present a framework for facilitating virtual aortic stenting from a…

Computer Vision and Pattern Recognition · Computer Science 2011-03-10 Jan Egger , Bernd Freisleben , Randolph Setser , Rahul Renapuraar , Christina Biermann , Thomas O'Donnell

In this work we study the hemodynamics in a stented artery connected either to a collateral artery or to an aneurysmal sac. The blood flow is driven by the pressure drop. Our aim is to characterize the flow-rate and the pressure in the…

Analysis of PDEs · Mathematics 2010-07-07 Vuk Milisic

Although projection-based reduced-order models (ROMs) for parameterized nonlinear dynamical systems have demonstrated exciting results across a range of applications, their broad adoption has been limited by their intrusivity: implementing…

Machine Learning · Computer Science 2021-06-18 Zhe Bai , Liqian Peng

Robot-assisted deployment of fenestrated stent grafts in Fenestrated Endovascular Aortic Repair (FEVAR) requires accurate geometrical alignment. Currently, this process is guided by 2D fluoroscopy, which is uninformative and error prone. In…

Robotics · Computer Science 2018-09-12 Xiao-Yun Zhou , Jianyu Lin , Celia Riga , Guang-Zhong Yang , Su-Lin Lee

Bioresorbable scaffolds have become a popular choice for treatment of coronary heart disease, replacing traditional metal stents. Often, intravascular optical coherence tomography is used to assess potential malapposition after implantation…

Computer Vision and Pattern Recognition · Computer Science 2018-10-24 Nils Gessert , Sarah Latus , Youssef S. Abdelwahed , David M. Leistner , Matthias Lutz , Alexander Schlaefer

Intracranial aneurysms are common nowadays and how to detect them intelligently is of great significance in digital health. While most existing deep learning research focused on medical images in a supervised way, we introduce an…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Di Shao , Xuequan Lu , Xiao Liu

Referral workflow inefficiencies, including misaligned referrals and delays, contribute to suboptimal patient outcomes and higher healthcare costs. In this study, we investigated the possibility of predicting procedural needs based on…

We propose a method to construct a reduced order model with machine learning for unsteady flows. The present machine-learned reduced order model (ML-ROM) is constructed by combining a convolutional neural network autoencoder (CNN-AE) and a…

Fluid Dynamics · Physics 2020-10-26 Kazuto Hasegawa , Kai Fukami , Takaaki Murata , Koji Fukagata

State estimation is key to both analyzing physical mechanisms and enabling real-time control of fluid flows. A common estimation approach is to relate sensor measurements to a reduced state governed by a reduced-order model (ROM). (When…

Fluid Dynamics · Physics 2020-06-10 Nirmal J. Nair , Andres Goza

Stenting is among the most common transcatheter interventions for congenital heart disease (CHD). Patient-specific computational fluid dynamics (CFD) simulations can predict hemodynamic outcomes of intervention scenarios but require…

Computational Engineering, Finance, and Science · Computer Science 2026-05-22 Bohan J. Li , Nicholas C. Dorn , Andras Lasso , Matthew A. Jolley , Jeffrey A. Feinstein , Doug L. James , Alison L. Marsden

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

Endovascular treatment of cerebral aneurysms aims to achieve functional occlusion and isolation of the aneurysm sac from bloodflow. In clinical practice, treatment success is assessed primarily through digital subtraction angiography (DSA),…

Computational Engineering, Finance, and Science · Computer Science 2026-05-06 Fabian Holzberger , Struan Hume , Markus Muhr , Malebogo Ngoepe , Barbara Wohlmuth

Advances in computational science offer a principled pipeline for predictive modeling of cardiovascular flows and aspire to provide a valuable tool for monitoring, diagnostics and surgical planning. Such models can be nowadays deployed on…

Machine Learning · Computer Science 2019-09-19 Georgios Kissas , Yibo Yang , Eileen Hwuang , Walter R. Witschey , John A. Detre , Paris Perdikaris

Three-dimensional (3D) finite-element simulations of cardiovascular flows provide high-fidelity predictions to support cardiovascular medicine, but their high computational cost limits clinical practicality. Reduced-order models (ROMs)…

Computational Engineering, Finance, and Science · Computer Science 2025-09-01 Natalia L. Rubio , Eric F. Darve , Alison L. Marsden

Establishing patient-specific finite element analysis (FEA) models for computational fluid dynamics (CFD) of double stenosed artery models involves time and effort, restricting physicians' ability to respond quickly in time-critical medical…

Medical Physics · Physics 2022-02-18 Ishat Raihan Jamil , Mayeesha Humaira

Development of in silico models are intrinsic in understanding disease progression in soft biological tissues. Within this work, we propose a fully-coupled Lagrangian finite element framework which replicates the process of in-stent…

Computational Engineering, Finance, and Science · Computer Science 2022-04-08 Kiran Manjunatha , Marek Behr , Felix Vogt , Stefanie Reese

The objective of this paper is to design novel multi-layer neural network architectures for multiscale simulations of flows taking into account the observed data and physical modeling concepts. Our approaches use deep learning concepts…

Numerical Analysis · Mathematics 2018-06-14 Yating Wang , Siu Wun Cheung , Eric T. Chung , Yalchin Efendiev , Min Wang