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Purpose: To study the effects of magnetization transfer (MT, in which a semisolid spin pool interacts with the free pool), in the context of magnetic resonance fingerprinting (MRF). Methods: Simulations and phantom experiments were…

Image and Video Processing · Electrical Eng. & Systems 2024-05-14 Tom Hilbert , Ding Xia , Kai Tobias Block , Zidan Yu , Riccardo Lattanzi , Daniel K. Sodickson , Tobias Kober , Martijn A. Cloos

Purpose: To identify the predominant source of the $T_1$ variability described in the literature, which ranges from 0.6-1.1 s for brain white matter at 3 T. Methods: 25 $T_1$-mapping methods from the literature were simulated with a…

Medical Physics · Physics 2025-01-07 Jakob Assländer

Purpose: To explore efficient encoding schemes for quantitative magnetization transfer (qMT) imaging with few constraints on model Theory and Methods: We combine two recently proposed models in a Bloch-McConnell equation: the dynamics of…

Purpose: Inhomogeneous magnetization transfer (ihMT) effect reflects dipolar order with a dipolar relaxation time ($T_{1D}$), specific to motion-restricted macromolecules. We aim to quantify $T_{1D}$ using spin-lock MRI technique. Methods:…

Medical Physics · Physics 2026-01-06 Zijian Gao , Qianxue Shan , Ziqin Zhou , Ziqiang Yu , Weitian Chen

Purpose: Recent studies have shown that spin-lock MRI can simplify quantitative magnetization transfer (MT) by eliminating its dependency on water pool parameters, removing the need for a T1 map in macromolecular proton fraction (MPF)…

Purpose: Magnetization transfer (MT) has been identified as the principal source of $T_1$ variability in the MRI literature. This study assesses the sensitivity of established $T_1$ mapping techniques to variations in the underlying MT…

Medical Physics · Physics 2025-12-15 Jakob Assländer

Purpose: The paper introduces a classical model to describe the dynamics of large spin-1/2 ensembles associated with nuclei bound in large molecule structures, commonly referred to as the semi-solid spin pool, and their magnetization…

Quantitative magnetization transfer (MT) imaging enables non-invasive characterization of the macromolecular environment of tissues. However, recent work has highlighted that the quantification of MT parameters exhibits orientation…

Medical Physics · Physics 2025-10-06 Zijian Gao , Ziqiang Yu , Ziqin Zhou , Jian Hou , Baiyan Jiang , Michael Ong , Weitian Chen

Quantitative magnetic resonance imaging might provide a more specific insight into disease process, progression and therapeutic response of multiple sclerosis. We present an extension of a previously published approach for the simultaneous…

Recovering the T2 distribution from multi-echo T2 magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this…

Purpose: Recent work highlights the breadth of reported spin-lattice relaxation rates ($R_1$) for individual tissues. One potential source of variation is the protocol used to determine $R_1$. The methodological dependence of R1 and…

Medical Physics · Physics 2019-10-01 Christopher Jenkins , Ioannis Papadopoulos , S. M. Shermer

Quantitative magnetization transfer (qMT) imaging provides myelin-sensitive biomarkers, such as the pool size ratio (PSR), which is valuable for multiple sclerosis (MS) assessment. However, qMT requires specialized 20-30 minute scans. We…

Image and Video Processing · Electrical Eng. & Systems 2025-11-27 Jiacheng Wang , Hao Li , Xing Yao , Ahmad Toubasi , Taegan Vinarsky , Caroline Gheen , Joy Derwenskus , Chaoyang Jin , Richard Dortch , Junzhong Xu , Francesca Bagnato , Ipek Oguz

We present an experimental and theoretical study of the longitudinal electron spin relaxation ($T_1$) of shallow donors in the direct band-gap semiconductor ZnO. $T_1$ is measured via resonant excitation of the Ga donor-bound exciton. $T_1$…

Purpose: To estimate fiber-specific $T_1$ values, i.e. proxies for myelin content, in heterogeneous brain tissue. Methods: A diffusion-$T_1$ correlation experiment was carried out on an in vivo human brain using tensor-valued diffusion…

Medical Physics · Physics 2021-04-02 A. Reymbaut , J. Critchley , G. Durighel , T. Sprenger , M. Sughrue , K. Bryskhe , D. Topgaard

We present a systematic ab initio investigation of the longitudinal and transverse spin relaxation times of magnetic single adatoms deposited on metallic substrates. Our analysis based on time-dependent density functional theory shows that…

Mesoscale and Nanoscale Physics · Physics 2017-10-11 J. Ibañez-Azpiroz , M. dos Santos Dias , S. Blügel , S. Lounis

A room temperature nuclear magnetic resonance force microscope (MRFM), fitted in a $^1$Tesla electromagnet, is used to measure the nuclear spin relaxation of $^1$H in a micron-size (70ng) crystal of ammonium sulfate. NMR sequences,…

Condensed Matter · Physics 2009-10-31 O. Klein , V. V. Naletov , H. Alloul

An important step towards a comprehensive understanding of far-from-equilibrium dynamics of quantum many-body systems is the identification of unifying features that are independent of microscopic details of the system. We experimentally…

An atomistic method of calculating the spin-lattice relaxation times ($T_1$) is presented for donors in silicon nanostructures comprising of millions of atoms. The method takes into account the full band structure of silicon including the…

Mesoscale and Nanoscale Physics · Physics 2015-01-19 Yu-Ling Hsueh , Holger Büch , Yaohua Tan , Yu Wang , Lloyd C. L. Hollenberg , Gerhard Klimeck , Michelle Y. Simmons , Rajib Rahman

Using the nascent concept of quantum spin-transfer torque [A. Zholud et al., Phys. Rev. Lett. {\bf 119}, 257201 (2017); M. D. Petrovi\'{c} {\em et al.}, Phys. Rev. X {\bf 11}, 021062 (2021)], we demonstrate that a current pulse can be…

We present a microscopic analysis of electron spin dynamics in the presence of an external magnetic field for non-centrosymmetric semiconductors in which the D'yakonov-Perel' spin-orbit interaction is the dominant spin relaxation mechanism.…

Condensed Matter · Physics 2017-08-23 Vadim I. Puller , Lev G. Mourokh , Anatoly Yu. Smirnov , Norman J. M. Horing
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