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Mechanistic cardiac electrophysiology models allow for personalized simulations of the electrical activity in the heart and the ensuing electrocardiogram (ECG) on the body surface. As such, synthetic signals possess known ground truth…

Synthesizing realistic microstructure images conditioned on processing parameters is crucial for understanding process-structure relationships in materials design. However, this task remains challenging due to limited training micrographs…

Materials Science · Physics 2025-11-21 Hoang Cuong Phan , Minh Tien Tran , Chihun Lee , Hoheok Kim , Sehyeok Oh , Dong-Kyu Kim , Ho Won Lee

Generative models can produce synthetic patient records for analytical tasks when real data is unavailable or limited. However, current methods struggle with adhering to domain-specific knowledge and removing invalid data. We present…

Machine Learning · Computer Science 2023-12-22 Brandon Theodorou , Shrusti Jain , Cao Xiao , Jimeng Sun

Synthetic data is becoming an increasingly promising technology, and successful applications can improve privacy, fairness, and data democratization. While there are many methods for generating synthetic tabular data, the task remains…

Machine Learning · Computer Science 2023-02-27 Alexander Norcliffe , Bogdan Cebere , Fergus Imrie , Pietro Lio , Mihaela van der Schaar

The electrocardiogram (ECG) records electrical signals in a non-invasive way to observe the condition of the heart, typically looking at the heart from 12 different directions. Several types of the cardiac disease are diagnosed by using…

Signal Processing · Electrical Eng. & Systems 2024-10-16 Yong-Yeon Jo , Young Sang Choi , Jong-Hwan Jang , Joon-Myoung Kwon

The generation of high-quality medical time series data is essential for advancing healthcare diagnostics and safeguarding patient privacy. Specifically, synthesizing realistic phonocardiogram (PCG) signals offers significant potential as a…

Machine Learning · Computer Science 2024-12-24 Ainaz Jamshidi , Muhammad Arif , Sabir Ali Kalhoro , Alexander Gelbukh

Generating graph-structured data requires learning the underlying distribution of graphs. Yet, this is a challenging problem, and the previous graph generative methods either fail to capture the permutation-invariance property of graphs or…

Machine Learning · Computer Science 2022-06-16 Jaehyeong Jo , Seul Lee , Sung Ju Hwang

The generation of synthetic medical records using Generative Adversarial Networks (GANs) is becoming crucial for addressing privacy concerns and facilitating data sharing in the medical domain. In this paper, we introduce a novel method to…

Image and Video Processing · Electrical Eng. & Systems 2023-09-20 Tomohiro Kikuchi , Shouhei Hanaoka , Takahiro Nakao , Tomomi Takenaga , Yukihiro Nomura , Harushi Mori , Takeharu Yoshikawa

Despite the remarkable generative capabilities of diffusion models, their integration into safety-critical or scientifically rigorous applications remains hindered by the need to ensure compliance with stringent physical, structural, and…

Machine Learning · Computer Science 2025-06-03 Jacob K. Christopher , Michael Cardei , Jinhao Liang , Ferdinando Fioretto

Recent advances in denoising diffusion probabilistic models have shown great success in image synthesis tasks. While there are already works exploring the potential of this powerful tool in image semantic segmentation, its application in…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Xinrong Hu , Yu-Jen Chen , Tsung-Yi Ho , Yiyu Shi

Obtaining per-beat information is a key task in the analysis of cardiac electrocardiograms (ECG), as many downstream diagnosis tasks are dependent on ECG-based measurements. Those measurements, however, are costly to produce, especially in…

Machine Learning · Computer Science 2022-06-14 Guillermo Jimenez-Perez , Juan Acosta , Alejandro Alcaine , Oscar Camara

Accurate forecasting of spatiotemporal data remains challenging due to complex spatial dependencies and temporal dynamics. The inherent uncertainty and variability in such data often render deterministic models insufficient, prompting a…

Machine Learning · Computer Science 2024-11-05 Mingze Gong , Lei Chen , Jia Li

Diffusion models have emerged as powerful tools for high-quality image generation and editing, but guiding these models to produce specific outputs remains a challenge. Conventional approaches rely on conditioning mechanisms, such as text…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Nithesh Chandher Karthikeyan , Jonas Unger , Gabriel Eilertsen

Reliable machine learning and statistical analysis rely on diverse, well-distributed training data. However, real-world datasets are often limited in size and exhibit underrepresentation across key subpopulations, leading to biased…

Methodology · Statistics 2025-07-15 Xinyu Tian , Xiaotong Shen

Synthetic data generation is increasingly used in machine learning for training and data augmentation. Yet, current strategies often rely on external foundation models or datasets, whose usage is restricted in many scenarios due to policy…

Computer Vision and Pattern Recognition · Computer Science 2025-10-27 Parsa Rahimi , Sebastien Marcel

Can continuous diffusion models bring the same performance breakthrough on natural language they did for image generation? To circumvent the discrete nature of text data, we can simply project tokens in a continuous space of embeddings, as…

Histopathology image classification is crucial for the accurate identification and diagnosis of various diseases but requires large and diverse datasets. Obtaining such datasets, however, is often costly and time-consuming due to the need…

Computer Vision and Pattern Recognition · Computer Science 2024-09-25 Leire Benito-Del-Valle , Aitor Alvarez-Gila , Itziar Eguskiza , Cristina L. Saratxaga

Synthetic Data Generation (SDG), leveraging Large Language Models (LLMs), has recently been recognized and broadly adopted as an effective approach to improve the performance of smaller but more resource and compute efficient LLMs through…

Machine Learning · Computer Science 2026-03-25 Srideepika Jayaraman , Achille Fokoue , Dhaval Patel , Jayant Kalagnanam

Diffusion generative models transform noise into data by inverting a process that progressively adds noise to data samples. Inspired by concepts from the renormalization group in physics, which analyzes systems across different scales, we…

Machine Learning · Computer Science 2024-10-04 Mathis Gerdes , Max Welling , Miranda C. N. Cheng

Recent advances in diffusion models attempt to handle conditional generative tasks by utilizing a differentiable loss function for guidance without the need for additional training. While these methods achieved certain success, they often…

Machine Learning · Computer Science 2024-07-08 Lingxiao Yang , Shutong Ding , Yifan Cai , Jingyi Yu , Jingya Wang , Ye Shi