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An electrocardiogram (ECG) is vital for identifying cardiac diseases, offering crucial insights for diagnosing heart conditions and informing potentially life-saving treatments. However, like other types of medical data, ECGs are subject to…

Signal Processing · Electrical Eng. & Systems 2024-07-17 Sergey Skorik , Aram Avetisyan

The development of machine learning for cardiac care is severely hampered by privacy restrictions on sharing real patient electrocardiogram (ECG) data. Although generative AI offers a promising solution, the real-world use of existing…

Data scarcity in the brain-computer interface field can be alleviated through the use of generative models, specifically diffusion models. While diffusion models have previously been successfully applied to electroencephalogram (EEG) data,…

Machine Learning · Computer Science 2024-11-05 Guido Klein , Pierre Guetschel , Gianluigi Silvestri , Michael Tangermann

Generating synthetic ECG data has numerous applications in healthcare, from educational purposes to simulating scenarios and forecasting trends. While recent diffusion models excel at generating short ECG segments, they struggle with longer…

Signal Processing · Electrical Eng. & Systems 2025-05-27 Paul Pöhl , Viktor Schlegel , Hao Li , Anil Bharath

Electroencephalography (EEG) is a widely used, non-invasive method for capturing brain activity, and is particularly relevant for applications in Brain-Computer Interfaces (BCI). However, collecting high-quality EEG data remains a major…

Signal Processing · Electrical Eng. & Systems 2025-10-22 Henrique de Lima Alexandre , Clodoaldo Aparecido de Moraes Lima

Electroencephalography (EEG) plays a significant role in the Brain Computer Interface (BCI) domain, due to its non-invasive nature, low cost, and ease of use, making it a highly desirable option for widespread adoption by the general…

Signal Processing · Electrical Eng. & Systems 2023-03-13 Giulio Tosato , Cesare M. Dalbagno , Francesco Fumagalli

Electrocardiogram (ECG) datasets tend to be highly imbalanced due to the scarcity of abnormal cases. Additionally, the use of real patients' ECGs is highly regulated due to privacy issues. Therefore, there is always a need for more ECG…

Machine Learning · Computer Science 2022-08-25 Edmond Adib , Fatemeh Afghah , John J. Prevost

High-quality synthetic data can support the development of effective predictive models for biomedical tasks, especially in rare diseases or when subject to compelling privacy constraints. These limitations, for instance, negatively impact…

Machine Learning · Computer Science 2023-01-24 Lorenzo Simone , Davide Bacciu

Within cardiovascular disease detection using deep learning applied to ECG signals, the complexities of handling physiological signals have sparked growing interest in leveraging deep generative models for effective data augmentation. In…

Computer Vision and Pattern Recognition · Computer Science 2024-05-06 Nour Neifar , Achraf Ben-Hamadou , Afef Mdhaffar , Mohamed Jmaiel

Synthetic electrocardiogram generation serves medical AI applications requiring privacy-preserving data sharing and training dataset augmentation. Current diffusion-based methods achieve high generation quality but require hundreds of…

Signal Processing · Electrical Eng. & Systems 2025-09-16 Vitalii Bondar , Serhii Semenov , Vira Babenko , Dmytro Holovniak

Personalized electrocardiogram (ECG) generation is to simulate a patient's ECG digital twins tailored to specific conditions. It has the potential to transform traditional healthcare into a more accurate individualized paradigm, while…

Machine Learning · Computer Science 2026-02-03 Yongfan Lai , Bo Liu , Xinyan Guan , Qinghao Zhao , Hongyan Li , Shenda Hong

Deep learning image processing models have had remarkable success in recent years in generating high quality images. Particularly, the Improved Denoising Diffusion Probabilistic Models (DDPM) have shown superiority in image quality to the…

Signal Processing · Electrical Eng. & Systems 2023-05-23 Edmond Adib , Amanda Fernandez , Fatemeh Afghah , John Jeff Prevost

Due to patient privacy protection concerns, machine learning research in healthcare has been undeniably slower and limited than in other application domains. High-quality, realistic, synthetic electronic health records (EHRs) can be…

Machine Learning · Computer Science 2023-02-10 Huan He , Shifan Zhao , Yuanzhe Xi , Joyce C Ho

Heart disease remains a significant threat to human health. As a non-invasive diagnostic tool, the electrocardiogram (ECG) is one of the most widely used methods for cardiac screening. However, the scarcity of high-quality ECG data, driven…

Machine Learning · Computer Science 2025-07-22 Yongfan Lai , Jiabo Chen , Deyun Zhang , Yue Wang , Shijia Geng , Hongyan Li , Shenda Hong

Electronic health records (EHRs) are invaluable for clinical research, yet privacy concerns severely restrict data sharing. Synthetic data generation offers a promising solution, but EHRs present unique challenges: they contain both…

Machine Learning · Computer Science 2026-03-26 Shaonan Liu , Yuichiro Iwashita , Soichiro Nakako , Masakazu Iwamura , Koichi Kise

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

Machine Learning · Computer Science 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

Deep learning models need a sufficient amount of data in order to be able to find the hidden patterns in it. It is the purpose of generative modeling to learn the data distribution, thus allowing us to sample more data and augment the…

Machine Learning · Computer Science 2024-11-28 José Fernando Núñez , Jamie Arjona , Javier Béjar

Diffusion-based foundation models have recently garnered much attention in the field of generative modeling due to their ability to generate images of high quality and fidelity. Although not straightforward, their recent application to the…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Nikos Kostagiolas , Pantelis Georgiades , Yannis Panagakis , Mihalis A. Nicolaou

Generative models are used as an alternative data augmentation technique to alleviate the data scarcity problem faced in the medical imaging field. Diffusion models have gathered special attention due to their innovative generation…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Ricardo Montoya-del-Angel , Karla Sam-Millan , Joan C Vilanova , Robert Martí

Electronic health records (EHR) contain a wealth of biomedical information, serving as valuable resources for the development of precision medicine systems. However, privacy concerns have resulted in limited access to high-quality and…

Machine Learning · Computer Science 2024-03-26 Hongyi Yuan , Songchi Zhou , Sheng Yu
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