Related papers: Error probability amplification in cellular transl…
Due to large fluctuations in cellular environments, transfer of information in biological processes without regulation is inherently error-prone. The mechanistic details of error-reducing mechanisms in biological copying processes have been…
We present a detailed kinetic model for the Polymerase Chain Reaction, and model the probability of replication in terms of the physical parameters of the problem. Applying the theory of branching processes, we show the existance of a new…
Studies intended to estimate the effect of a treatment, like randomized trials, may not be sampled from the desired target population. To correct for this discrepancy, estimates can be transported to the target population. Methods for…
Traditionally, quantum amplification limit refers to the property of inevitable noise addition on canonical variables when the field amplitude of an unknown state is linearly transformed through a quantum channel. Recent theoretical studies…
Deprivation of essential nutrients can have stark consequences for many processes in a cell. We consider amino acid starvation, which can result in bottlenecks in mRNA translation when ribosomes stall due to lack of resources, i.e. tRNAs…
The information content of a non-enzymatic self-replicator is limited by Eigen's error threshold. Presumably, enzymatic replication can maintain higher complexity, but in a competitive environment such a replicator is faced with two…
Using tools developed in a recent work by Shen and the second author, in this paper we carry out an in-depth study on the average decoding error probability of the random matrix ensemble over the erasure channel under three decoding…
In engineering, it is a common desire to couple existing simulation tools together into one big system by passing information from subsystems as parameters into the subsystems under influence. As executed at fixed time points, this data…
Mixed sample data augmentation strategies are actively used when training deep neural networks (DNNs). Recent studies suggest that they are effective at various tasks. However, the impact of mixed sample data augmentation on model…
Excess of probabilities of elastic processes over inelastic ones is a characteristic feature of the chaotic resonance scattering predicted by the random matrix theory (RMT). Quantitatively, this phenomenon is characterized by the elastic…
Push-pull networks are ubiquitous in signal transduction pathways in both prokaryotic and eukaryotic cells. They allow cells to strongly amplify signals via the mechanism of zero-order ultrasensitivity. In a push-pull network, two…
Positive feedback and cooperativity in the regulation of gene expression are generally considered to be necessary for obtaining bistable expression states. Recently, a novel mechanism of bistability termed emergent bistability has been…
RNA can be used as a high-density medium for data storage and transmission; however, an important RNA process -- replication -- is noisy. This paper presents an error analysis for RNA as a data transmission medium, analyzing how deletion…
We consider the problem of estimating the probability of error in multi-hypothesis testing when MAP criterion is used. This probability, which is also known as the Bayes risk is an important measure in many communication and information…
Achieving precise synchronisation between transmitters and receivers is particularly challenging in diffusive molecular communication environments. To this end, point-to-point molecular communication system design is examined wherein…
Data augmentation is an effective performance enhancement in neural machine translation (NMT) by generating additional bilingual data. In this paper, we propose a novel data augmentation enhancement strategy for neural machine translation.…
Sampling and quantization are crucial in digital signal processing, but quantization introduces errors, particularly due to distribution mismatch between input signals and quantizers. Existing methods to reduce this error require precise…
Large scale surveys in mammalian tissue culture cells suggest that the protein expressed at the median abundance is present at 8,000 - 16,000 molecules per cell and that differences in mRNA expression between genes explain only 10-40% of…
Molecular biology explains function of molecules by their geometrical and electronical structures that are mainly determined by utilization of quantum effects in chemistry. However, further quantum effects are not thought to play any…
Entanglement assistance can improve communication rates significantly. Yet, its generation is susceptible to failure. The unreliable assistance model accounts for those challenges. Previous work provided an asymptotic formula that outlines…